| Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 DA Barbie, P Tamayo, JS Boehm, SY Kim, SE Moody, IF Dunn, ... Nature 462 (7269), 108-112, 2009 | 3389 | 2009 |
| WRN helicase is a synthetic lethal target in microsatellite unstable cancers EM Chan, T Shibue, JM McFarland, B Gaeta, M Ghandi, N Dumont, ... Nature 568 (7753), 551-556, 2019 | 327 | 2019 |
| Structure and ubiquitination-dependent activation of TANK-binding kinase 1 D Tu, Z Zhu, AY Zhou, C Yun, KE Lee, AV Toms, Y Li, GP Dunn, E Chan, ... Cell reports 3 (3), 747-758, 2013 | 214 | 2013 |
| Inhibition of KRAS-Driven Tumorigenicity by Interruption of an Autocrine Cytokine Circuit Z Zhu, AR Aref, TJ Cohoon, TU Barbie, Y Imamura, S Yang, SE Moody, ... Cancer discovery 4 (4), 452-465, 2014 | 209 | 2014 |
| Repeat expansions confer WRN dependence in microsatellite-unstable cancers N van Wietmarschen, S Sridharan, WJ Nathan, A Tubbs, EM Chan, ... Nature 586 (7828), 292-298, 2020 | 140 | 2020 |
| CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue J Gu, A Iyer, B Wesley, A Taglialatela, G Leuzzi, S Hangai, A Decker, ... bioRxiv, 2023 | 5 | 2023 |
| Mapping multimodal phenotypes to perturbations in cells and tissue with CRISPRmap J Gu, A Iyer, B Wesley, A Taglialatela, G Leuzzi, S Hangai, A Decker, ... Nature Biotechnology, 1-15, 2024 | 2 | 2024 |
| WRN Is a promising synthetic lethal target for cancers with microsatellite instability (MSI) EM Chan, KJ Foster, AJ Bass Targeting the DNA Damage Response for Cancer Therapy, 313-328, 2023 | 2 | 2023 |
| WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers A Bass, E Chan, T Shibue, J McFarland, B Gaeta, M Ghandi, N Dumont, ... Nature, 2018 | 1 | 2018 |
| PELO is a synthetic lethal target in chromosome 9p21-deleted or MSI cancers EM Chan, P Borck, N Bick, K Jankovic, I Boyle, L Parker-Burns, K Foster, ... Cancer Research 84 (6_Supplement), 3364-3364, 2024 | | 2024 |
| Single analyte profiling of the mutational, immune and microbiome landscape in african american colon cancer patients C Gurjao, E Chan, MJ Lee, S Hangai, R Rabadan, T Korem, H Hibshoosh, ... Cancer Research 84 (6_Supplement), 994-994, 2024 | | 2024 |
| Therapeutic treatment of microsatellite unstable cancers F Vazquez, A Bass, T Shibue, E Chan, J Mcfarland, M Ghandi, ... | | 2019 |
| Abstract LB-048: WRN helicase is a synthetic lethal target in microsatellite unstable cancers EM Chan, T Shibue, J McFarland, B Gaeta, F Vazquez, AJ Bass Cancer Research 79 (13_Supplement), LB-048-LB-048, 2019 | | 2019 |
