Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism J Aragonés, M Schneider, K Van Geyte, P Fraisl, T Dresselaers, ... Nature genetics 40 (2), 170-180, 2008 | 564 | 2008 |
Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2 BH Herzog, J Fu, SJ Wilson, PR Hess, A Sen, JM McDaniel, Y Pan, ... Nature 502 (7469), 105-109, 2013 | 360 | 2013 |
Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice J Fu, H Gerhardt, JM McDaniel, B Xia, X Liu, L Ivanciu, A Ny, K Hermans, ... The Journal of clinical investigation 118 (11), 3725-3737, 2008 | 272 | 2008 |
Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis R Silasi-Mansat, H Zhu, NI Popescu, G Peer, G Sfyroera, P Magotti, ... Blood, The Journal of the American Society of Hematology 116 (6), 1002-1010, 2010 | 209 | 2010 |
Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling S Pasula, X Cai, Y Dong, M Messa, J McManus, B Chang, X Liu, H Zhu, ... The Journal of clinical investigation 122 (12), 4424-4438, 2012 | 124 | 2012 |
Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis RS Keshari, R Silasi, NI Popescu, MM Patel, H Chaaban, C Lupu, ... Proceedings of the National Academy of Sciences 114 (31), E6390-E6399, 2017 | 99 | 2017 |
Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development X Geng, B Cha, MR Mahamud, KC Lim, R Silasi-Mansat, MKM Uddin, ... Developmental biology 409 (1), 218-233, 2016 | 97 | 2016 |
ELTD1, a potential new biomarker for gliomas RA Towner, RL Jensen, H Colman, B Vaillant, N Smith, R Casteel, ... Neurosurgery 72 (1), 77-91, 2013 | 88 | 2013 |
Inter-α inhibitor protein and its associated glycosaminoglycans protect against histone-induced injury H Chaaban, RS Keshari, R Silasi-Mansat, NI Popescu, P Mehta-D’Souza, ... Blood, The Journal of the American Society of Hematology 125 (14), 2286-2296, 2015 | 82 | 2015 |
Profibrotic infrapatellar fat pad remodeling without m1 macrophage polarization precedes knee osteoarthritis in mice with diet‐induced obesity E Barboza, J Hudson, WP Chang, S Kovats, RA Towner, R Silasi‐Mansat, ... Arthritis & Rheumatology 69 (6), 1221-1232, 2017 | 76 | 2017 |
In vivo detection of c‐Met expression in a rat C6 glioma model RA Towner, N Smith, S Doblas, Y Tesiram, P Garteiser, D Saunders, ... Journal of cellular and molecular medicine 12 (1), 174-186, 2008 | 70 | 2008 |
Polycystic disease caused by deficiency in xylosyltransferase 2, an initiating enzyme of glycosaminoglycan biosynthesis E Condac, R Silasi-Mansat, S Kosanke, T Schoeb, R Towner, F Lupu, ... Proceedings of the National Academy of Sciences 104 (22), 9416-9421, 2007 | 70 | 2007 |
The safety and efficacy of novel agents targeting factors XI and XII in early phase human trials EP DeLoughery, SR Olson, C Puy, OJT McCarty, JJ Shatzel Seminars in thrombosis and hemostasis 45 (05), 502-508, 2019 | 60 | 2019 |
Inhibition of contact-mediated activation of factor XI protects baboons against S aureus–induced organ damage and death R Silasi, RS Keshari, C Lupu, WJ Van Rensburg, H Chaaban, G Regmi, ... Blood advances 3 (4), 658-669, 2019 | 58 | 2019 |
Notch3 Arg170Cys knock-in mice display pathologic and clinical features of the neurovascular disorder cerebral autosomal dominant arteriopathy with subcortical infarcts and … G Wallays, D Nuyens, R Silasi-Mansat, J Souffreau, Z Callaerts-Vegh, ... Arteriosclerosis, thrombosis, and vascular biology 31 (12), 2881-2888, 2011 | 51 | 2011 |
Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice Y Jiang, Y Tang, C Hoover, Y Kondo, D Huang, D Restagno, B Shao, ... Cell Death & Differentiation 28 (11), 3009-3021, 2021 | 50 | 2021 |
Acute Lung Injury and Fibrosis in a Baboon Model of Escherichia coli Sepsis RS Keshari, R Silasi-Mansat, H Zhu, NI Popescu, G Peer, H Chaaban, ... American journal of respiratory cell and molecular biology 50 (2), 439-450, 2014 | 47 | 2014 |
The NuRD chromatin-remodeling enzyme CHD4 promotes embryonic vascular integrity by transcriptionally regulating extracellular matrix proteolysis KG Ingram, CD Curtis, R Silasi-Mansat, F Lupu, CT Griffin PLoS genetics 9 (12), e1004031, 2013 | 46 | 2013 |
Complement inhibition decreases early fibrogenic events in the lung of septic baboons R Silasi‐Mansat, H Zhu, C Georgescu, N Popescu, RS Keshari, G Peer, ... Journal of cellular and molecular medicine 19 (11), 2549-2563, 2015 | 43 | 2015 |
In vivo detection of free radicals using molecular MRI and immuno-spin trapping in a mouse model for amyotrophic lateral sclerosis RA Towner, N Smith, D Saunders, F Lupu, R Silasi-Mansat, M West, ... Free Radical Biology and Medicine 63, 351-360, 2013 | 42 | 2013 |