Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine M Raffatellu, MD George, Y Akiyama, MJ Hornsby, SP Nuccio, TA Paixao, ... Cell host & microbe 5 (5), 476-486, 2009 | 578 | 2009 |
Redox-based reagents for chemoselective methionine bioconjugation S Lin, X Yang, S Jia, AM Weeks, M Hornsby, PS Lee, RV Nichiporuk, ... Science 355 (6325), 597-602, 2017 | 457 | 2017 |
A high through-put platform for recombinant antibodies to folded proteins M Hornsby, M Paduch, S Miersch, A Sääf, T Matsuguchi, B Lee, ... Molecular & Cellular Proteomics 14 (10), 2833-2847, 2015 | 115 | 2015 |
Identification of selective, nonpeptidic nitrile inhibitors of cathepsin S using the substrate activity screening method AW Patterson, WJL Wood, M Hornsby, S Lesley, G Spraggon, JA Ellman Journal of medicinal chemistry 49 (21), 6298-6307, 2006 | 113 | 2006 |
Identification of coumarin derivatives as a novel class of allosteric MEK1 inhibitors S Han, V Zhou, S Pan, Y Liu, M Hornsby, D McMullan, HE Klock, ... Bioorganic & medicinal chemistry letters 15 (24), 5467-5473, 2005 | 106 | 2005 |
Helicobacter pylori induces an antimicrobial response in rhesus macaques in a cag pathogenicity island-dependent manner MJ Hornsby, JL Huff, RJ Kays, DR Canfield, CL Bevins, JV Solnick Gastroenterology 134 (4), 1049-1057, 2008 | 102 | 2008 |
Crystal structure of human Pus10, a novel pseudouridine synthase CJ McCleverty, M Hornsby, G Spraggon, A Kreusch Journal of molecular biology 373 (5), 1243-1254, 2007 | 94 | 2007 |
An improved single-chain Fab platform for efficient display and recombinant expression JT Koerber, MJ Hornsby, JA Wells Journal of molecular biology 427 (2), 576-586, 2015 | 73 | 2015 |
Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 Å resolution reveals a new fold C Rife, R Schwarzenbacher, D McMullan, P Abdubek, E Ambing, ... Proteins: Structure, Function, and Bioinformatics 61 (2), 449-453, 2005 | 63 | 2005 |
Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies SB Pollock, A Hu, Y Mou, AJ Martinko, O Julien, M Hornsby, L Ploder, ... Proceedings of the National Academy of Sciences 115 (11), 2836-2841, 2018 | 50 | 2018 |
Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations G Spraggon, M Hornsby, A Shipway, DC Tully, B Bursulaya, H Danahay, ... Protein Science 18 (5), 1081-1094, 2009 | 50 | 2009 |
Three essential resources to improve differential scanning fluorimetry (DSF) experiments T Wu, J Yu, Z Gale-Day, A Woo, A Suresh, M Hornsby, JE Gestwicki BioRxiv, 2020.03. 22.002543, 2020 | 46 | 2020 |
Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 Å resolution Q Xu, R Schwarzenbacher, S Sri Krishna, D McMullan, S Agarwalla, ... Proteins: Structure, Function, and Bioinformatics 64 (3), 808-813, 2006 | 44 | 2006 |
Scalable high throughput selection from phage-displayed synthetic antibody libraries S Miersch, Z Li, R Hanna, ME McLaughlin, M Hornsby, T Matsuguchi, ... Journal of visualized experiments: JoVE, 2015 | 43 | 2015 |
Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode H Inagaki, H Tsuruoka, M Hornsby, SA Lesley, G Spraggon, JA Ellman Journal of medicinal chemistry 50 (11), 2693-2699, 2007 | 41 | 2007 |
Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers DC Tully, H Liu, AK Chatterjee, PB Alper, R Epple, JA Williams, ... Bioorganic & medicinal chemistry letters 16 (19), 5112-5117, 2006 | 39 | 2006 |
Biochemical basis for distinct roles of the heterochromatin proteins Swi6 and Chp2 RS Isaac, S Sanulli, R Tibble, M Hornsby, M Ravalin, CS Craik, JD Gross, ... Journal of molecular biology 429 (23), 3666-3677, 2017 | 28 | 2017 |
Determination of equilibrium dissociation constants for recombinant antibodies by high-throughput affinity electrophoresis Y Pan, EK Sackmann, K Wypisniak, M Hornsby, SS Datwani, AE Herr Scientific Reports 6 (1), 39774, 2016 | 28 | 2016 |
Evidence of convergent evolution in humans and macaques supports an adaptive role for copy number variation of the β-defensin-2 gene B Ottolini, MJ Hornsby, R Abujaber, JAL MacArthur, RM Badge, ... Genome biology and evolution 6 (11), 3025-3038, 2014 | 25 | 2014 |
Crystal structure of S‐adenosylmethionine:tRNA ribosyltransferase‐isomerase (QueA) from Thermotoga maritima at 2.0 Å resolution reveals a new fold I Mathews, R Schwarzenbacher, D McMullan, P Abdubek, E Ambing, ... Proteins: Structure, Function, and Bioinformatics 59 (4), 869-874, 2005 | 21 | 2005 |