Aptamers in the therapeutics and diagnostics pipelines H Kaur, JG Bruno, A Kumar, TK Sharma Theranostics 8 (15), 4016, 2018 | 331 | 2018 |
Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif–ligand database and chemical similarity searching R Parkesh, JL Childs-Disney, M Nakamori, A Kumar, E Wang, T Wang, ... Journal of the American Chemical Society 134 (10), 4731-4742, 2012 | 146 | 2012 |
Discovery of New Hydroxyethylamine Analogs against 3CLpro Protein Target of SARS-CoV-2: Molecular Docking, Molecular Dynamics Simulation, and Structure … S Kumar, PP Sharma, U Shankar, D Kumar, SK Joshi, L Pena, ... Journal of Chemical Information and Modeling 60 (12), 5754-5770, 2020 | 121 | 2020 |
G4IPDB: A database for G-quadruplex structure forming nucleic acid interacting proteins SK Mishra, A Tawani, A Mishra, A Kumar Scientific reports 6 (1), 38144, 2016 | 116 | 2016 |
Chemical correction of pre-mRNA splicing defects associated with sequestration of muscleblind-like 1 protein by expanded r (CAG)-containing transcripts A Kumar, R Parkesh, LJ Sznajder, JL Childs-Disney, K Sobczak, ... ACS chemical biology 7 (3), 496-505, 2012 | 92 | 2012 |
Structural insight for the recognition of G-quadruplex structure at human c-myc promoter sequence by flavonoid Quercetin AK A Tawani, SK Mishra Scientific Reports 7 (1), 3600, 2017 | 76 | 2017 |
Evidences for Piperine inhibiting cancer by targeting human G-quadruplex DNA sequences A Tawani, A Amanullah, A Mishra, A Kumar Scientific Reports, 2016 | 75 | 2016 |
Structural insight into the interaction of flavonoids with human telomeric sequence A Tawani, A Kumar Scientific Reports 5 (1), 17574, 2015 | 72 | 2015 |
A decade of boon or burden: what has the CHIP ever done for cellular protein quality control mechanism implicated in neurodegeneration and aging? V Joshi, A Amanullah, A Upadhyay, R Mishra, A Kumar, A Mishra Frontiers in molecular neuroscience 9, 93, 2016 | 67 | 2016 |
Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects JW Hoskins, LO Ofori, CZ Chen, A Kumar, K Sobczak, M Nakamori, ... Nucleic acids research 42 (10), 6591-6602, 2014 | 64 | 2014 |
A novel G-quadruplex aptamer-based spike trimeric antigen test for the detection of SARS-CoV-2 A Gupta, A Anand, N Jain, S Goswami, A Anantharaj, S Patil, R Singh, ... Molecular Therapy-Nucleic Acids 26, 321-332, 2021 | 55 | 2021 |
Characterization of G-quadruplex motifs in espB, espK and cyp51 genes of Mycobacterium tuberculosis as a potential drug targets, AK S. K. Mishra, U. Shankar, N. Jain, E. Khan, K. Sikri, J. S. Tyagi, T. K ... Molecular Therapy-Nucleic Acids, 2019 | 54 | 2019 |
Polyphenolic Flavonoid (Myricetin) Upregulated Proteasomal Degradation Mechanisms: Eliminates Neurodegenerative Proteins Aggregation, V. Joshi, R. Mishra, A. Upadhyay, A. Amanullah, K. M. Poluri, S. Singh, Amit ... Journal of Cellular Physiology,, 2019 | 53 | 2019 |
Myotonic dystrophy type 1 RNA crystal structures reveal heterogeneous 1× 1 nucleotide UU internal loop conformations A Kumar, HJ Park, P Fang, R Parkesh, M Guo, KW Nettles, MD Disney Biochemistry 50 (45), 9928-9935, 2011 | 53 | 2011 |
Characterization of highly conserved G-quadruplex motifs as potential drug targets in Streptococcus pneumoniae SK Mishra, N Jain, U Shankar, A Tawani, TK Sharma, A Kumar Scientific Reports 9 (1), 1791, 2019 | 50 | 2019 |
Multifunctional inosine monophosphate coordinated metal–organic hydrogel: Multistimuli responsiveness, self-healing properties, and separation of water from organic solvents N Thakur, B Sharma, S Bishnoi, SK Mishra, D Nayak, A Kumar, TK Sarma ACS sustainable chemistry & engineering 6 (7), 8659-8671, 2018 | 48 | 2018 |
Gp78 E3 Ubiquitin Ligase: Essential Functions and Contributions In Proteostasis AM Vibhuti Joshi, Arun Upadhyay, Amit Kumar Frontiers in Cellular Neuroscience, 2017 | 48 | 2017 |
G-quadruplex structures in bacteria: biological relevance and potential as an antimicrobial target P Yadav, N Kim, M Kumari, S Verma, TK Sharma, V Yadav, A Kumar Journal of Bacteriology 203 (13), 10.1128/jb. 00577-20, 2021 | 46 | 2021 |
Identification and characterization of two conserved G-quadruplex forming motifs in the Nipah virus genome and their interaction with G-quadruplex specific ligands P Majee, S Kumar Mishra, N Pandya, U Shankar, S Pasadi, K Muniyappa, ... Scientific reports 10 (1), 1477, 2020 | 45 | 2020 |
Inhibition of Zika Virus Replication by G-Quadruplex Binding Ligands P Majee, A Pattnaik, BR Sahoo, U Shankar, AK Pattnaik, A Kumar, ... Molecular Therapy-Nucleic Acids, 2021 | 44 | 2021 |