Restoration of p53 function leads to tumour regression in vivo A Ventura, DG Kirsch, ME McLaughlin, DA Tuveson, J Grimm, L Lintault, ... Nature 445 (7128), 661-665, 2007 | 2130 | 2007 |
Targeted deletion reveals essential and overlapping functions of the miR-17∼ 92 family of miRNA clusters A Ventura, AG Young, MM Winslow, L Lintault, A Meissner, SJ Erkeland, ... Cell 132 (5), 875-886, 2008 | 2009 | 2008 |
MicroRNAs and cancer: short RNAs go a long way A Ventura, T Jacks Cell 136 (4), 586-591, 2009 | 1065 | 2009 |
Cre-lox-regulated conditional RNA interference from transgenes A Ventura, A Meissner, CP Dillon, M McManus, PA Sharp, L Van Parijs, ... Proceedings of the National Academy of Sciences 101 (28), 10380-10385, 2004 | 747 | 2004 |
In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system D Maddalo, E Manchado, CP Concepcion, C Bonetti, JA Vidigal, YC Han, ... Nature 516 (7531), 423-427, 2014 | 732 | 2014 |
Genetic dissection of the miR-17∼ 92 cluster of microRNAs in Myc-induced B-cell lymphomas P Mu, YC Han, D Betel, E Yao, M Squatrito, P Ogrodowski, ... Genes & development 23 (24), 2806-2811, 2009 | 593 | 2009 |
The biological functions of miRNAs: lessons from in vivo studies JA Vidigal, A Ventura Trends in cell biology 25 (3), 137-147, 2015 | 542 | 2015 |
A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis M Trinei, M Giorgio, A Cicalese, S Barozzi, A Ventura, E Migliaccio, ... Oncogene 21 (24), 3872-3878, 2002 | 530 | 2002 |
Widespread regulatory activity of vertebrate microRNA* species JS Yang, MD Phillips, D Betel, P Mu, A Ventura, AC Siepel, KC Chen, ... Rna 17 (2), 312-326, 2011 | 472 | 2011 |
Pan-cancer alterations of the MYC oncogene and its proximal network across the cancer genome atlas FX Schaub, V Dhankani, AC Berger, M Trivedi, AB Richardson, R Shaw, ... Cell systems 6 (3), 282-300. e2, 2018 | 369 | 2018 |
Germline deletion of the miR-17∼ 92 cluster causes skeletal and growth defects in humans L de Pontual, E Yao, P Callier, L Faivre, V Drouin, S Cariou, ... Nature genetics 43 (10), 1026-1030, 2011 | 361 | 2011 |
The microRNA-17-92 family of microRNA clusters in development and disease CP Concepcion, C Bonetti, A Ventura The Cancer Journal 18 (3), 262-267, 2012 | 347 | 2012 |
Capture of microRNA–bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling A Lal, MP Thomas, G Altschuler, F Navarro, E O'Day, XL Li, C Concepcion, ... PLoS genetics 7 (11), e1002363, 2011 | 283 | 2011 |
GuideScan software for improved single and paired CRISPR guide RNA design A Perez, Y Pritykin, J Vidigal, S Chhangawala, L Zamparo, C Leslie, ... Nature Biotechnology, 347-349, 2017 | 240 | 2017 |
Mammalian RNAi: a practical guide P Sandy, A Ventura, T Jacks Biotechniques 39 (2), 215-224, 2005 | 231 | 2005 |
Intact p53-dependent responses in miR-34–deficient mice CP Concepcion, YC Han, P Mu, C Bonetti, E Yao, A D'andrea, JA Vidigal, ... PLoS genetics 8 (7), e1002797, 2012 | 230 | 2012 |
microRNA-34a regulates neurite outgrowth, spinal morphology, and function M Agostini, P Tucci, JR Steinert, R Shalom-Feuerstein, M Rouleau, ... Proceedings of the National Academy of Sciences 108 (52), 21099-21104, 2011 | 225 | 2011 |
The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter A Ventura, L Luzi, S Pacini, CT Baldari, PG Pelicci Journal of Biological Chemistry 277 (25), 22370-22376, 2002 | 218 | 2002 |
Rapid and efficient one-step generation of paired gRNA CRISPR-Cas9 libraries JA Vidigal, A Ventura Nature communications 6 (1), 8083, 2015 | 170 | 2015 |
p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells S Pacini, M Pellegrini, E Migliaccio, L Patrussi, C Ulivieri, A Ventura, ... Molecular and Cellular Biology 24 (4), 1747-1757, 2004 | 163 | 2004 |