Antitumor antibiotics: bleomycin, enediynes, and mitomycin U Galm, MH Hager, SG Van Lanen, J Ju, JS Thorson, B Shen Chemical reviews 105 (2), 739-758, 2005 | 648 | 2005 |
Microbial genome mining for accelerated natural products discovery: is a renaissance in the making? BO Bachmann, SG Van Lanen, RH Baltz Journal of industrial Microbiology and Biotechnology 41 (2), 175-184, 2014 | 328 | 2014 |
Microbial genomics for the improvement of natural product discovery SG Van Lanen, B Shen Current opinion in microbiology 9 (3), 252-260, 2006 | 218 | 2006 |
Characterization of the Maduropeptin Biosynthetic Gene Cluster from Actinomadura madurae ATCC 39144 Supporting a Unifying Paradigm for Enediyne … SG Van Lanen, T Oh, W Liu, E Wendt-Pienkowski, B Shen Journal of the American Chemical Society 129 (43), 13082-13094, 2007 | 158 | 2007 |
The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases W Liu, K Nonaka, L Nie, J Zhang, SD Christenson, J Bae, SG Van Lanen, ... Chemistry & biology 12 (3), 293-302, 2005 | 146 | 2005 |
Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S‐Adenosyl‐L‐Methionine Analogues S Singh, J Zhang, TD Huber, M Sunkara, K Hurley, RD Goff, G Wang, ... Angewandte Chemie International Edition 53 (15), 3965-3969, 2014 | 144 | 2014 |
From cyclohydrolase to oxidoreductase: discovery of nitrile reductase activity in a common fold SG Van Lanen, JS Reader, MA Swairjo, V de Crécy-Lagard, B Lee, ... Proceedings of the National Academy of Sciences 102 (12), 4264-4269, 2005 | 135 | 2005 |
Biosynthesis of enediyne antitumor antibiotics SG Van Lanen, B Shen Current topics in medicinal chemistry 8 (6), 448-459, 2008 | 118 | 2008 |
Enzymatic strategies and biocatalysts for amide bond formation: tricks of the trade outside of the ribosome A Goswami, SG Van Lanen Molecular BioSystems 11 (2), 338-353, 2015 | 113 | 2015 |
Regiospecific Chlorination of (S)-β-Tyrosyl-S-Carrier Protein Catalyzed by SgcC3 in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 S Lin, SG Van Lanen, B Shen Journal of the American Chemical Society 129 (41), 12432-12438, 2007 | 112 | 2007 |
A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis J Zhang, SG Van Lanen, J Ju, W Liu, PC Dorrestein, W Li, NL Kelleher, ... Proceedings of the National Academy of Sciences 105 (5), 1460-1465, 2008 | 109 | 2008 |
The role of tandem acyl carrier protein domains in polyunsaturated fatty acid biosynthesis H Jiang, R Zirkle, JG Metz, L Braun, L Richter, SG Van Lanen, B Shen Journal of the American Chemical Society 130 (20), 6336-6337, 2008 | 104 | 2008 |
A free-standing condensation enzyme catalyzing ester bond formation in C-1027 biosynthesis S Lin, SG Van Lanen, B Shen Proceedings of the National Academy of Sciences 106 (11), 4183-4188, 2009 | 91 | 2009 |
The Structure of l-Tyrosine 2,3-Aminomutase from the C-1027 Enediyne Antitumor Antibiotic Biosynthetic Pathway, CV Christianson, TJ Montavon, SG Van Lanen, B Shen, SD Bruner Biochemistry 46 (24), 7205-7214, 2007 | 82 | 2007 |
Amalgamation of Nucleosides and Amino Acids in Antibiotic Biosynthesis: Discovery of an l-Threonine:Uridine-5′-Aldehyde Transaldolase S Barnard-Britson, X Chi, K Nonaka, AP Spork, N Tibrewal, A Goswami, ... Journal of the American Chemical Society 134 (45), 18514-18517, 2012 | 81 | 2012 |
An ATP-independent strategy for amide bond formation in antibiotic biosynthesis M Funabashi, Z Yang, K Nonaka, M Hosobuchi, Y Fujita, T Shibata, X Chi, ... Nature chemical biology 6 (8), 581-586, 2010 | 76 | 2010 |
Mechanistic studies of Bacillus subtilis QueF, the nitrile oxidoreductase involved in queuosine biosynthesis BWK Lee, SG Van Lanen, D Iwata-Reuyl Biochemistry 46 (44), 12844-12854, 2007 | 76 | 2007 |
Biosynthesis of Albomycin δ2 Provides a Template for Assembling Siderophore and Aminoacyl-tRNA Synthetase Inhibitor Conjugates Y Zeng, A Kulkarni, Z Yang, PB Patil, W Zhou, X Chi, S Van Lanen, ... ACS chemical biology 7 (9), 1565-1575, 2012 | 73 | 2012 |
Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis P Pahari, MK Kharel, MD Shepherd, SG van Lanen, J Rohr Angewandte Chemie (International ed. in English) 51 (5), 1216, 2012 | 71 | 2012 |
Characterization of LipL as a non-heme, Fe (II)-dependent α-ketoglutarate: UMP dioxygenase that generates uridine-5′-aldehyde during A-90289 biosynthesis Z Yang, X Chi, M Funabashi, S Baba, K Nonaka, P Pahari, J Unrine, ... Journal of Biological Chemistry 286 (10), 7885-7892, 2011 | 68 | 2011 |