关注
Steven G. Van Lanen
Steven G. Van Lanen
在 uky.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Antitumor antibiotics: bleomycin, enediynes, and mitomycin
U Galm, MH Hager, SG Van Lanen, J Ju, JS Thorson, B Shen
Chemical reviews 105 (2), 739-758, 2005
6482005
Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?
BO Bachmann, SG Van Lanen, RH Baltz
Journal of industrial Microbiology and Biotechnology 41 (2), 175-184, 2014
3282014
Microbial genomics for the improvement of natural product discovery
SG Van Lanen, B Shen
Current opinion in microbiology 9 (3), 252-260, 2006
2182006
Characterization of the Maduropeptin Biosynthetic Gene Cluster from Actinomadura madurae ATCC 39144 Supporting a Unifying Paradigm for Enediyne …
SG Van Lanen, T Oh, W Liu, E Wendt-Pienkowski, B Shen
Journal of the American Chemical Society 129 (43), 13082-13094, 2007
1582007
The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases
W Liu, K Nonaka, L Nie, J Zhang, SD Christenson, J Bae, SG Van Lanen, ...
Chemistry & biology 12 (3), 293-302, 2005
1462005
Facile Chemoenzymatic Strategies for the Synthesis and Utilization of S‐Adenosyl‐L‐Methionine Analogues
S Singh, J Zhang, TD Huber, M Sunkara, K Hurley, RD Goff, G Wang, ...
Angewandte Chemie International Edition 53 (15), 3965-3969, 2014
1442014
From cyclohydrolase to oxidoreductase: discovery of nitrile reductase activity in a common fold
SG Van Lanen, JS Reader, MA Swairjo, V de Crécy-Lagard, B Lee, ...
Proceedings of the National Academy of Sciences 102 (12), 4264-4269, 2005
1352005
Biosynthesis of enediyne antitumor antibiotics
SG Van Lanen, B Shen
Current topics in medicinal chemistry 8 (6), 448-459, 2008
1182008
Enzymatic strategies and biocatalysts for amide bond formation: tricks of the trade outside of the ribosome
A Goswami, SG Van Lanen
Molecular BioSystems 11 (2), 338-353, 2015
1132015
Regiospecific Chlorination of (S)-β-Tyrosyl-S-Carrier Protein Catalyzed by SgcC3 in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027
S Lin, SG Van Lanen, B Shen
Journal of the American Chemical Society 129 (41), 12432-12438, 2007
1122007
A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis
J Zhang, SG Van Lanen, J Ju, W Liu, PC Dorrestein, W Li, NL Kelleher, ...
Proceedings of the National Academy of Sciences 105 (5), 1460-1465, 2008
1092008
The role of tandem acyl carrier protein domains in polyunsaturated fatty acid biosynthesis
H Jiang, R Zirkle, JG Metz, L Braun, L Richter, SG Van Lanen, B Shen
Journal of the American Chemical Society 130 (20), 6336-6337, 2008
1042008
A free-standing condensation enzyme catalyzing ester bond formation in C-1027 biosynthesis
S Lin, SG Van Lanen, B Shen
Proceedings of the National Academy of Sciences 106 (11), 4183-4188, 2009
912009
The Structure of l-Tyrosine 2,3-Aminomutase from the C-1027 Enediyne Antitumor Antibiotic Biosynthetic Pathway,
CV Christianson, TJ Montavon, SG Van Lanen, B Shen, SD Bruner
Biochemistry 46 (24), 7205-7214, 2007
822007
Amalgamation of Nucleosides and Amino Acids in Antibiotic Biosynthesis: Discovery of an l-Threonine:Uridine-5′-Aldehyde Transaldolase
S Barnard-Britson, X Chi, K Nonaka, AP Spork, N Tibrewal, A Goswami, ...
Journal of the American Chemical Society 134 (45), 18514-18517, 2012
812012
An ATP-independent strategy for amide bond formation in antibiotic biosynthesis
M Funabashi, Z Yang, K Nonaka, M Hosobuchi, Y Fujita, T Shibata, X Chi, ...
Nature chemical biology 6 (8), 581-586, 2010
762010
Mechanistic studies of Bacillus subtilis QueF, the nitrile oxidoreductase involved in queuosine biosynthesis
BWK Lee, SG Van Lanen, D Iwata-Reuyl
Biochemistry 46 (44), 12844-12854, 2007
762007
Biosynthesis of Albomycin δ2 Provides a Template for Assembling Siderophore and Aminoacyl-tRNA Synthetase Inhibitor Conjugates
Y Zeng, A Kulkarni, Z Yang, PB Patil, W Zhou, X Chi, S Van Lanen, ...
ACS chemical biology 7 (9), 1565-1575, 2012
732012
Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis
P Pahari, MK Kharel, MD Shepherd, SG van Lanen, J Rohr
Angewandte Chemie (International ed. in English) 51 (5), 1216, 2012
712012
Characterization of LipL as a non-heme, Fe (II)-dependent α-ketoglutarate: UMP dioxygenase that generates uridine-5′-aldehyde during A-90289 biosynthesis
Z Yang, X Chi, M Funabashi, S Baba, K Nonaka, P Pahari, J Unrine, ...
Journal of Biological Chemistry 286 (10), 7885-7892, 2011
682011
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