| Mapping intact protein isoforms in discovery mode using top-down proteomics JC Tran, L Zamdborg, DR Ahlf, JE Lee, AD Catherman, KR Durbin, ... Nature 480 (7376), 254-258, 2011 | 770 | 2011 |
| Quantitative measurement of intact alpha-synuclein proteoforms from post-mortem control and Parkinson's disease brain tissue by intact protein mass spectrometry JF Kellie, RE Higgs, JW Ryder, A Major, TG Beach, CH Adler, K Merchant, ... Scientific reports 4 (1), 5797, 2014 | 172 | 2014 |
| The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput JF Kellie, JC Tran, JE Lee, DR Ahlf, HM Thomas, I Ntai, AD Catherman, ... Molecular BioSystems 6 (9), 1532-1539, 2010 | 133 | 2010 |
| Size-sorting combined with improved nanocapillary liquid chromatography− mass spectrometry for identification of intact proteins up to 80 kDa A Vellaichamy, JC Tran, AD Catherman, JE Lee, JF Kellie, SMM Sweet, ... Analytical chemistry 82 (4), 1234-1244, 2010 | 115 | 2010 |
| A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome JE Lee, JF Kellie, JC Tran, JD Tipton, AD Catherman, HM Thomas, ... Journal of the American Society for Mass Spectrometry 20, 2183-2191, 2009 | 111 | 2009 |
| Robust analysis of the yeast proteome under 50 kDa by molecular-mass-based fractionation and top-down mass spectrometry JF Kellie, AD Catherman, KR Durbin, JC Tran, JD Tipton, JL Norris, ... Analytical chemistry 84 (1), 209-215, 2012 | 67 | 2012 |
| Intact mass detection, interpretation, and visualization to automate Top‐Down proteomics on a large scale KR Durbin, JC Tran, L Zamdborg, SMM Sweet, AD Catherman, JE Lee, ... Proteomics 10 (20), 3589-3597, 2010 | 58 | 2010 |
| Nano-LC FTICR tandem mass spectrometry for top-down proteomics: routine baseline unit mass resolution of whole cell lysate proteins up to 72 kDa JD Tipton, JC Tran, AD Catherman, DR Ahlf, KR Durbin, JE Lee, JF Kellie, ... Analytical chemistry 84 (5), 2111-2117, 2012 | 48 | 2012 |
| A Whole-Molecule Immunocapture LC–MS Approach for The In Vivo Quantitation of Biotherapeutics JF Kellie, JR Kehler, TJ Mencken, RJ Snell, CS Hottenstein Bioanalysis 8 (20), 2103-2114, 2016 | 42 | 2016 |
| Intact protein mass spectrometry for therapeutic protein quantitation, pharmacokinetics, and biotransformation in preclinical and clinical studies: an industry perspective JF Kellie, JC Tran, W Jian, B Jones, JT Mehl, Y Ge, J Henion, KP Bateman Journal of the American Society for Mass Spectrometry 32 (8), 1886-1900, 2020 | 30 | 2020 |
| IQ consortium perspective: complementary LBA and LC–MS in protein therapeutics bioanalysis and biotransformation assessment S Kaur, KP Bateman, J Glick, M Jairaj, J F Kellie, J Sydor, J Zeng Bioanalysis 12 (4), 257-270, 2020 | 28 | 2020 |
| 2019 White paper on recent issues in bioanalysis: chromatographic assays (part 1–innovation in small molecules and oligonucleotides & mass spectrometric method development … C Fandozzi, C Evans, A Wilson, D Su, M Anderson, V Clausen, L Dillen, ... Bioanalysis 11 (22), 2029-2048, 2019 | 28 | 2019 |
| Drug monitoring by volumetric absorptive microsampling: method development considerations to mitigate hematocrit effects K Fang, CL Bowen, JF Kellie, MZ Karlinsey, CA Evans Bioanalysis 10 (4), 241-255, 2018 | 27 | 2018 |
| Application of high-resolution MS for development of peptide and large-molecule drug candidates JF Kellie, JR Kehler, ME Szapacs Bioanalysis 8 (3), 169-177, 2016 | 25 | 2016 |
| Toward best practices in data processing and analysis for intact biotherapeutics by MS in quantitative bioanalysis JF Kellie, JR Kehler, MZ Karlinsey, SG Summerfield Bioanalysis 9 (23), 1883-1893, 2017 | 24 | 2017 |
| Review of approaches and examples for monitoring biotransformation in protein and peptide therapeutics by MS JF Kellie, MZ Karlinsey Bioanalysis 10 (22), 1877-1890, 2018 | 21 | 2018 |
| 2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH M10 Section 7.1 … S Kaur, SC Alley, M Szapacs, A Wilson, E Ciccimaro, D Su, N Henderson, ... Bioanalysis 14 (9), 505-580, 2022 | 20 | 2022 |
| Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid H Lee, HV Le, R Wu, E Doud, R Sanishvili, JF Kellie, PD Compton, ... ACS chemical biology 10 (9), 2087-2098, 2015 | 20 | 2015 |
| Antibody subunit LC-MS analysis for pharmacokinetic and biotransformation determination from in-life studies for complex biotherapeutics JF Kellie, KE Pannullo, Y Li, K Fraley, A Mayer, CJ Sychterz, ME Szapacs, ... Analytical Chemistry 92 (12), 8268-8277, 2020 | 17 | 2020 |
| Biotherapeutic antibody subunit LC-MS and peptide mapping LC-MS measurements to study possible biotransformation and critical quality attributes in vivo JF Kellie, AS Thomson, S Chen, SL Childs, MZ Karlinsey, SH Mai, ... Journal of Pharmaceutical Sciences 108 (4), 1415-1422, 2019 | 15 | 2019 |
