Transcellular delivery of vesicular SOCS proteins from macrophages to epithelial cells blunts inflammatory signaling E Bourdonnay, Z Zasłona, LRK Penke, JM Speth, DJ Schneider, ... Journal of Experimental Medicine 212 (5), 729-742, 2015 | 229 | 2015 |
Reversal of Myofibroblast Differentiation by Prostaglandin E2 G Garrison, SK Huang, K Okunishi, JP Scott, LR Kumar Penke, ... American journal of respiratory cell and molecular biology 48 (5), 550-558, 2013 | 153 | 2013 |
FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis LR Penke, JM Speth, VL Dommeti, ES White, IL Bergin, M Peters-Golden The Journal of Clinical Investigation 128 (6), 2389-2405, 2018 | 103 | 2018 |
Prostaglandin E2 inhibits α-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin … LRK Penke, SK Huang, ES White, M Peters-Golden Journal of Biological Chemistry 289 (24), 17151-17162, 2014 | 91 | 2014 |
Mechanisms and modulation of microvesicle uptake in a model of alveolar cell communication DJ Schneider, JM Speth, LR Penke, SH Wettlaufer, JA Swanson, ... Journal of Biological Chemistry 292 (51), 20897-20910, 2017 | 79 | 2017 |
Myofibroblast de-differentiation proceeds via distinct transcriptomic and phenotypic transitions. S Fortier, LRK Penke, D King, T Pham, G Ligresti, M Peters-Golden JCI Insight, https://insight.jci.org/articles/view/14, 2021 | 58 | 2021 |
Distinctive Effects of GM-CSF and M-CSF on Proliferation and Polarization of Two Major Pulmonary Macrophage Populations C Draijer, LRK Penke, M Peters-Golden Journal of Immunology 202 (9), 2700-2709, 2019 | 58 | 2019 |
Alveolar epithelial cell–derived prostaglandin E2 serves as a request signal for macrophage secretion of suppressor of cytokine signaling 3 during innate inflammation JM Speth, E Bourdonnay, LRK Penke, P Mancuso, BB Moore, ... The Journal of Immunology 196 (12), 5112-5120, 2016 | 47 | 2016 |
Inhibition of IL-2 induced IL-10 production as a principle of phase-specific immunotherapy M Bodas, N Jain, A Awasthi, S Martin, RK Penke Loka, D Dandekar, ... The Journal of Immunology 177 (7), 4636-4643, 2006 | 46 | 2006 |
Resident Alveolar Macrophage-Derived Vesicular SOCS3 Dampens, but is Deficient in, Allergic Airway Inflammation. C Draijer, JM Speth, LRK Penke, Z Zaslona, JD Bazzill, N Lugogo, ... FASEB J., 2020 | 38* | 2020 |
Megakaryocytes compensate for Kit insufficiency in murine arthritis P Cunin, LR Penke, JN Thon, PA Monach, T Jones, MH Chang, MM Chen, ... The Journal of clinical investigation 127 (5), 1714-1724, 2017 | 35 | 2017 |
Molecular determinants of mesenchymal cell activation in fibroproliferative diseases LR Penke, M Peters-Golden Cell Mol Life Sci. 76 (21), 4179-4201, 2019 | 31 | 2019 |
Alveolar macrophage secretion of vesicular SOCS3 represents a platform for lung cancer therapeutics JM Speth, LR Penke, JD Bazzill, KS Park, RG de Rubio, DJ Schneider, ... JCI Insight. 2019 Oct 17;4(20). pii: 131340., 2019 | 30 | 2019 |
Antifibrotic factor KLF4 is repressed by the miR-10/TFAP2A/TBX5 axis in dermal fibroblasts: insights from twins discordant for systemic sclerosis M Malaab, L Renaud, N Takamura, KD Zimmerman, WA da Silveira, ... Annals of the rheumatic diseases 81 (2), 268-277, 2022 | 28 | 2022 |
Bortezomib Inhibits Lung Fibrosis and Fibroblast Activation Without Proteasome Inhibition LRK Penke, J Speth, W Scott, D Christina, M Peters-Golden The American Journal of Respiratory Cell and Molecular Biology 66 (1), 23-37., 2021 | 17 | 2021 |
KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis LR Penke, JM Speth, SK Huang, SM Fortier, J Baas, M Peters-Golden JCI insight 7 (16), 2022 | 15 | 2022 |
PGE2 accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking LR Penke, JM Speth, C Draijer, Z Zaslona, J Chen, P Mancuso, ... Life Science Alliance 3 (11), 2020 | 13 | 2020 |
Prostaglandin E2 receptors have differential effects on Leishmania major infection LR Penke, R Sudan, S Sathishkumar, B Saha Parasite immunology 35 (1), 51-54, 2013 | 13 | 2013 |
Distinct PKA regulatory subunits mediate PGE2 inhibition of TGFβ-1-stimulated collagen I translation and myofibroblast differentiation. SH Wettlaufer, LR Penke, K Okunishi, M Peters-Golden Am J Physiol Lung Cell Mol Physiol. 313 (4), L722-L731., 2017 | 12 | 2017 |
Alveolar Macrophage-Derived Extracellular Vesicles Inhibit Endosomal Fusion of Influenza Virus DJ Schneider, KA Smith, CE Latuszek, CA Wilke, DM Lyons, LR Penke, ... EMBO, 2020 | 10 | 2020 |