A mild, chemoselective oxidation of sulfides to sulfoxides using o-iodoxybenzoic acid and tetraethylammonium bromide as catalyst VG Shukla, PD Salgaonkar, KG Akamanchi The Journal of organic chemistry 68 (13), 5422-5425, 2003 | 182 | 2003 |
Δ9-Tetrahydrocannabinol acts as a partial agonist/antagonist in mice CA Paronis, SP Nikas, VG Shukla, A Makriyannis Behavioural pharmacology 23 (8), 802-805, 2012 | 106 | 2012 |
Novel 1′, 1′-chain substituted hexahydrocannabinols: 9β-hydroxy-3-(1-hexyl-cyclobut-1-yl)-hexahydrocannabinol (AM2389) a highly potent cannabinoid receptor 1 (CB1) agonist SP Nikas, SO Alapafuja, I Papanastasiou, CA Paronis, VG Shukla, ... Journal of medicinal chemistry 53 (19), 6996-7010, 2010 | 72 | 2010 |
Equipotent inhibition of fatty acid amide hydrolase and monoacylglycerol lipase–dual targets of the endocannabinoid system to protect against seizure pathology V Naidoo, DA Karanian, SK Vadivel, JR Locklear, JAT Wood, M Nasr, ... Neurotherapeutics 9 (4), 801-813, 2012 | 61 | 2012 |
Sulfonyl fluoride inhibitors of fatty acid amide hydrolase SO Alapafuja, SP Nikas, IT Bharathan, VG Shukla, ML Nasr, AL Bowman, ... Journal of medicinal chemistry 55 (22), 10074-10089, 2012 | 56 | 2012 |
Cannabinoid discrimination and antagonism by CB1 neutral and inverse agonist antagonists BD Kangas, MS Delatte, VK Vemuri, GA Thakur, SP Nikas, ... Journal of Pharmacology and Experimental Therapeutics 344 (3), 561-567, 2013 | 45 | 2013 |
Comparisons of Δ9-tetrahydrocannabinol and anandamide on a battery of cognition-related behavior in nonhuman primates BD Kangas, MZ Leonard, VG Shukla, SO Alapafuja, SP Nikas, ... Journal of Pharmacology and Experimental Therapeutics 357 (1), 125-133, 2016 | 39 | 2016 |
A novel and one step procedure for preparation of α-bromo-α, β-unsaturated carbonyl compounds GV Ramanarayanan, VG Shukla, KG Akamanchi Synlett 2002 (12), 2059-2061, 2002 | 36 | 2002 |
AM2389, a high-affinity, in vivo potent CB1-receptor-selective cannabinergic ligand as evidenced by drug discrimination in rats and hypothermia testing in mice TUC Järbe, S Tai, BJ LeMay, SP Nikas, VG Shukla, A Zvonok, ... Psychopharmacology 220, 417-426, 2012 | 35 | 2012 |
C3-heteroaroyl cannabinoids as photolabeling ligands for the CB2 cannabinoid receptor DD Dixon, MA Tius, GA Thakur, H Zhou, AL Bowman, VG Shukla, Y Peng, ... Bioorganic & medicinal chemistry letters 22 (16), 5322-5325, 2012 | 33 | 2012 |
Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor DR Janero, S Yaddanapudi, N Zvonok, KV Subramanian, VG Shukla, ... ACS chemical neuroscience 6 (8), 1400-1410, 2015 | 32 | 2015 |
Cannabinoid withdrawal in mice: inverse agonist vs neutral antagonist S Tai, SP Nikas, VG Shukla, K Vemuri, A Makriyannis, TUC Järbe Psychopharmacology 232, 2751-2761, 2015 | 26 | 2015 |
Microwave-assisted synthesis of sodium sulfonates precursors of sulfonyl chlorides and fluorides SO Alapafuja, SP Nikas, VG Shukla, I Papanastasiou, A Makriyannis Tetrahedron letters 50 (50), 7028-7031, 2009 | 20 | 2009 |
A first example using o-iodoxybenzoic acid (IBX) in combination with tetraethylammonium bromide (TEAB) for ring expansion of 1, 3-dithiolanes and 1, 3-dithianes VG Shukla, PD Salgaonkar, KG Akamanchi Synlett 2005 (09), 1483-1485, 2005 | 20 | 2005 |
α‐Bromination of 1, 3‐Dicarbonyl Compounds Using Dess–Martin Periodinane (DMP) and Tetraethylammonium Bromide (TEAB) PD Salgaonkar, VG Shukla, KG Akamanchi Synthetic communications 37 (2), 275-280, 2007 | 16 | 2007 |
Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology M Lamani, MS Malamas, SI Farah, VG Shukla, MF Almeida, CM Weerts, ... Bioorganic & medicinal chemistry 27 (23), 115096, 2019 | 13 | 2019 |
Inhibitor of endocannabinoid deactivation protects against in vitro and in vivo neurotoxic effects of paraoxon KLG Farizatto, SA McEwan, V Naidoo, SP Nikas, VG Shukla, MF Almeida, ... Journal of Molecular Neuroscience 63, 115-122, 2017 | 13 | 2017 |
Endocannabinoid enzyme engineering: soluble human thio-monoacylglycerol lipase (sol-S-hMGL) I Karageorgos, N Zvonok, DR Janero, VK Vemuri, V Shukla, TE Wales, ... ACS chemical neuroscience 3 (5), 393-399, 2012 | 13 | 2012 |
Cannabinoid CB1 discrimination: effects of endocannabinoids and catabolic enzyme inhibitors MZ Leonard, SO Alapafuja, L Ji, VG Shukla, Y Liu, SP Nikas, ... Journal of Pharmacology and Experimental Therapeutics 363 (3), 314-323, 2017 | 11 | 2017 |
Iodic Acid (HIO3) in Combination with Tetraethylammonium Bromide as a Catalyst for Selective and Accelerated Sulfoxidation PD Salgaonkar, VG Shukla, KG Akamanchi Synthetic communications 35 (21), 2805-2810, 2005 | 11 | 2005 |