A novel computational model of the human ventricular action potential and Ca transient E Grandi, FS Pasqualini, JL Puglisi, DM Bers Biophysical journal 96 (3), 664a-665a, 2009 | 556 | 2009 |
Human Atrial Action Potential and Ca2+ Model: Sinus Rhythm and Chronic Atrial Fibrillation E Grandi, SV Pandit, N Voigt, AJ Workman, D Dobrev, J Jalife, DM Bers Circulation research 109 (9), 1055-1066, 2011 | 444 | 2011 |
Reactive Oxygen Species–Activated Ca/Calmodulin Kinase IIδ Is Required for Late INa Augmentation Leading to Cellular Na and Ca Overload S Wagner, HM Ruff, SL Weber, S Bellmann, T Sowa, T Schulte, ... Circulation research 108 (5), 555-565, 2011 | 324 | 2011 |
Ion channels in the heart DC Bartos, E Grandi, CM Ripplinger Comprehensive physiology 5 (3), 1423, 2015 | 253 | 2015 |
FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility NC Surdo, M Berrera, A Koschinski, M Brescia, MR Machado, C Carr, ... Nature communications 8 (1), 15031, 2017 | 198 | 2017 |
Calcium/calmodulin-dependent kinase II regulation of cardiac ion channels DM Bers, E Grandi Journal of cardiovascular pharmacology 54 (3), 180-187, 2009 | 185 | 2009 |
Ca/calmodulin kinase II differentially modulates potassium currents S Wagner, E Hacker, E Grandi, SL Weber, N Dybkova, S Sossalla, ... Circulation: Arrhythmia and Electrophysiology 2 (3), 285-294, 2009 | 161 | 2009 |
Patients with complex arrhythmias during and after haemodialysis suffer from different regimens of potassium removal A Santoro, E Mancini, G London, L Mercadal, H Fessy, B Perrone, ... Nephrology Dialysis Transplantation 23 (4), 1415-1421, 2008 | 130 | 2008 |
Simulation of Ca-calmodulin-dependent protein kinase II on rabbit ventricular myocyte ion currents and action potentials E Grandi, JL Puglisi, S Wagner, LS Maier, S Severi, DM Bers Biophysical journal 93 (11), 3835-3847, 2007 | 119 | 2007 |
Late Sodium Current Contributes to the Reverse Rate-Dependent Effect of IKr Inhibition on Ventricular Repolarization L Wu, J Ma, H Li, C Wang, E Grandi, P Zhang, A Luo, DM Bers, ... Circulation 123 (16), 1713-1720, 2011 | 117 | 2011 |
A computational model of induced pluripotent stem‐cell derived cardiomyocytes incorporating experimental variability from multiple data sources DC Kernik, S Morotti, HD Wu, P Garg, HJ Duff, J Kurokawa, J Jalife, ... The Journal of physiology 597 (17), 4533-4564, 2019 | 115 | 2019 |
Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes MA Nystoriak, M Nieves-Cintrón, T Patriarchi, OR Buonarati, MP Prada, ... Science signaling 10 (463), eaaf9647, 2017 | 113 | 2017 |
Potassium channels in the heart: structure, function and regulation E Grandi, MC Sanguinetti, DC Bartos, DM Bers, Y Chen‐Izu, ... The Journal of physiology 595 (7), 2209-2228, 2017 | 112 | 2017 |
A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII S Morotti, AG Edwards, AD McCulloch, DM Bers, E Grandi The Journal of physiology 592 (6), 1181-1197, 2014 | 111 | 2014 |
Calcium and potassium changes during haemodialysis alter ventricular repolarization duration: in vivo and in silico analysis S Severi, E Grandi, C Pes, F Badiali, F Grandi, A Santoro Nephrology Dialysis Transplantation 23 (4), 1378-1386, 2008 | 108 | 2008 |
Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics N Chiamvimonvat, Y Chen‐Izu, CE Clancy, I Deschenes, D Dobrev, ... The Journal of physiology 595 (7), 2229-2252, 2017 | 102 | 2017 |
Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias AW Herren, DM Bers, E Grandi American Journal of Physiology-Heart and Circulatory Physiology 305 (4 …, 2013 | 98 | 2013 |
Ranolazine for Congenital and Acquired Late INa-Linked Arrhythmias: In Silico Pharmacological Screening JD Moreno, PC Yang, JR Bankston, E Grandi, DM Bers, RS Kass, ... Circulation research 113 (7), e50-e61, 2013 | 96 | 2013 |
Na+ channel function, regulation, structure, trafficking and sequestration Y Chen‐Izu, RM Shaw, GS Pitt, V Yarov‐Yarovoy, JT Sack, H Abriel, ... The Journal of physiology 593 (6), 1347-1360, 2015 | 88 | 2015 |
β-adrenergic stimulation activates early afterdepolarizations transiently via kinetic mismatch of PKA targets Y Xie, E Grandi, JL Puglisi, D Sato, DM Bers Journal of molecular and cellular cardiology 58, 153-161, 2013 | 88 | 2013 |