Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human … NM Khan, A Haseeb, MY Ansari, P Devarapalli, S Haynie, TM Haqqi Free Radical Biology and Medicine 106, 288-301, 2017 | 266 | 2017 |
Directional dominance on stature and cognition in diverse human populations Nature, 2015 | 194 | 2015 |
Parkin clearance of dysfunctional mitochondria regulates ROS levels and increases survival of human chondrocytes MY Ansari, NM Khan, I Ahmad, TM Haqqi Osteoarthritis and cartilage 26 (8), 1087-1097, 2018 | 181 | 2018 |
Nrf2/ARE pathway attenuates oxidative and apoptotic response in human osteoarthritis chondrocytes by activating ERK1/2/ELK1-P70S6K-P90RSK signaling axis NM Khan, I Ahmad, TM Haqqi Free Radical Biology and Medicine 116, 159-171, 2018 | 115 | 2018 |
Pro-oxidants ameliorate radiation-induced apoptosis through activation of the calcium–ERK1/2–Nrf2 pathway NM Khan, SK Sandur, R Checker, D Sharma, TB Poduval, KB Sainis Free Radical Biology and Medicine 51 (1), 115-128, 2011 | 82 | 2011 |
Inhibition of cartilage degradation and suppression of PGE2 and MMPs expression by pomegranate fruit extract in a model of posttraumatic osteoarthritis N Akhtar, NM Khan, OS Ashruf, TM Haqqi Nutrition 33, 1-13, 2017 | 78 | 2017 |
Immunomodulatory and immunotoxic effects of bilirubin: molecular mechanisms NM Khan, TB Poduval Journal of Leukocyte Biology 90 (5), 997-1015, 2011 | 70 | 2011 |
Sucrose, but not glucose, blocks IL1‐β‐induced inflammatory response in human chondrocytes by inducing autophagy via AKT/mTOR pathway NM Khan, MY Ansari, TM Haqqi Journal of cellular biochemistry 118 (3), 629-639, 2017 | 60 | 2017 |
Epigenetics in osteoarthritis: potential of HDAC inhibitors as therapeutics NM Khan, TM Haqqi Pharmacological research 128, 73-79, 2018 | 51 | 2018 |
Deep sequencing and analyses of miRNAs, isomiRs and miRNA induced silencing complex (miRISC)-associated miRNome in primary human chondrocytes A Haseeb, MS Makki, NM Khan, I Ahmad, TM Haqqi Scientific reports 7 (1), 15178, 2017 | 46 | 2017 |
Autophagy plays an essential role in bone homeostasis FA Jaber, NM Khan, MY Ansari, AA Al‐Adlaan, NJ Hussein, FF Safadi Journal of Cellular Physiology, 2019 | 45 | 2019 |
Single-cell RNA-seq identifies unique transcriptional landscapes of human nucleus pulposus and annulus fibrosus cells LM Fernandes, NM Khan, CM Trochez, M Duan, ME Diaz-Hernandez, ... Scientific reports 10 (1), 15263, 2020 | 43 | 2020 |
Role of immunoregulatory transcription factors in differential immunomodulatory effects of tocotrienols C Wilankar, D Sharma, R Checker, NM Khan, R Patwardhan, A Patil, ... Free Radical Biology and Medicine 51 (1), 129-143, 2011 | 43 | 2011 |
Vitamin K3 suppressed inflammatory and immune responses in a redox-dependent manner R Checker, D Sharma, SK Sandur, NM Khan, RS Patwardhan, V Kohli, ... Free radical research 45 (8), 975-985, 2011 | 41 | 2011 |
A standardized extract of Butea monosperma (Lam.) flowers suppresses the IL-1β-induced expression of IL-6 and matrix-metalloproteases by activating autophagy in human … MY Ansari, NM Khan, TM Haqqi Biomedicine & Pharmacotherapy 96, 198-207, 2017 | 40 | 2017 |
A Wogonin-rich Fraction of scutellaria baicalensis Root Extract Exerts Chondroprotective Effects by Suppressing IL-1β-induced Activation of AP-1 in Human OA Chondrocytes TMH N.M. Khan, A. Haseeb, M.Y. Ansari Osteoarthritis and Cartilage 25 (Supplement 1), S292, 2017 | 40* | 2017 |
Genetic Epidemiology of Pharmacogenetic Variations in CYP2C9, CYP4F2 and VKORC1 Genes Associated with Warfarin Dosage in the Indian Population AK Giri, NM Khan, S Grover, I Kaur, A Basu, N Tandon, V Scaria, ... Pharmacogenomics 15 (10), 1337-1354, 2014 | 38 | 2014 |
γ-Tocotrienol induces apoptosis in human T cell lymphoma through activation of both intrinsic and extrinsic pathways C Wilankar, N M Khan, R Checker, D Sharma, R Patwardhan, V Gota, ... Current pharmaceutical design 17 (21), 2176-2189, 2011 | 37 | 2011 |
Wogonin, a natural flavonoid, intercalates with genomic DNA and exhibits protective effects in IL-1β stimulated osteoarthritis chondrocytes NM Khan, I Ahmad, MY Ansari, TM Haqqi Chemico-biological interactions 274, 13-23, 2017 | 33 | 2017 |
A polyphenol‐rich pomegranate fruit extract suppresses NF‐κB and IL‐6 expression by blocking the activation of IKKβ and NIK in primary human chondrocytes A Haseeb, NM Khan, OS Ashruf, TM Haqqi Phytotherapy Research 31 (5), 778-782, 2017 | 29 | 2017 |