Genetic effects on gene expression across human tissues GTEx Consortium Lead analysts: Aguet François 1 Brown Andrew A. 2 3 4 Castel ... Nature 550 (7675), 204-213, 2017 | 3357 | 2017 |
The GTEx Consortium atlas of genetic regulatory effects across human tissues GTEx Consortium Science 369 (6509), 1318-1330, 2020 | 2666 | 2020 |
A reference map of the human binary protein interactome K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ... Nature 580 (7803), 402-408, 2020 | 954 | 2020 |
The impact of sex on gene expression across human tissues M Oliva, M Muñoz-Aguirre, S Kim-Hellmuth, V Wucher, ADH Gewirtz, ... Science 369 (6509), eaba3066, 2020 | 722 | 2020 |
Network motifs in integrated cellular networks of transcription–regulation and protein–protein interaction E Yeger-Lotem, S Sattath, N Kashtan, S Itzkovitz, R Milo, RY Pinter, ... Proceedings of the National Academy of Sciences 101 (16), 5934-5939, 2004 | 692 | 2004 |
Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity E Yeger-Lotem, L Riva, LJ Su, AD Gitler, AG Cashikar, OD King, ... Nature genetics 41 (3), 316-323, 2009 | 333 | 2009 |
A quantitative proteome map of the human body L Jiang, M Wang, S Lin, R Jian, X Li, J Chan, G Dong, H Fang, ... Cell 183 (1), 269-283. e19, 2020 | 301 | 2020 |
Alignment of metabolic pathways RY Pinter, O Rokhlenko, E Yeger-Lotem, M Ziv-Ukelson Bioinformatics 21 (16), 3401-3408, 2005 | 280 | 2005 |
Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models LJ Su, PK Auluck, TF Outeiro, E Yeger-Lotem, JA Kritzer, DF Tardiff, ... Disease models & mechanisms 3 (3-4), 194-208, 2010 | 220 | 2010 |
Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes Y Elyahu, I Hekselman, I Eizenberg-Magar, O Berner, I Strominger, ... Science advances 5 (8), eaaw8330, 2019 | 199 | 2019 |
Co-expression networks reveal the tissue-specific regulation of transcription and splicing A Saha, Y Kim, ADH Gewirtz, B Jo, C Gao, IC McDowell, BE Engelhardt, ... Genome research 27 (11), 1843-1858, 2017 | 171 | 2017 |
Mechanisms of tissue and cell-type specificity in heritable traits and diseases I Hekselman, E Yeger-Lotem Nature Reviews Genetics 21 (3), 137-150, 2020 | 124 | 2020 |
Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease OM de Goede, DC Nachun, NM Ferraro, MJ Gloudemans, AS Rao, ... Cell 184 (10), 2633-2648. e19, 2021 | 122 | 2021 |
Cancer evolution is associated with pervasive positive selection on globally expressed genes SL Ostrow, R Barshir, J DeGregori, E Yeger-Lotem, R Hershberg PLoS genetics 10 (3), e1004239, 2014 | 119 | 2014 |
Transcriptomic signatures across human tissues identify functional rare genetic variation NM Ferraro, BJ Strober, J Einson, NS Abell, F Aguet, AN Barbeira, ... Science 369 (6509), eaaz5900, 2020 | 113 | 2020 |
Dynamic voting for consistent primary components D Dolev, I Keidar, EY Lotem Proceedings of the sixteenth annual ACM symposium on Principles of …, 1997 | 101 | 1997 |
Human protein interaction networks across tissues and diseases E Yeger-Lotem, R Sharan Frontiers in genetics 6, 257, 2015 | 93 | 2015 |
Comparative analysis of human tissue interactomes reveals factors leading to tissue-specific manifestation of hereditary diseases R Barshir, O Shwartz, IY Smoly, E Yeger-Lotem PLoS computational biology 10 (6), e1003632, 2014 | 92 | 2014 |
Chromosomal organization is shaped by the transcription regulatory network R Hershberg, E Yeger-Lotem, H Margalit Trends in genetics 21 (3), 138-142, 2005 | 88 | 2005 |
ResponseNet: revealing signaling and regulatory networks linking genetic and transcriptomic screening data A Lan, IY Smoly, G Rapaport, S Lindquist, E Fraenkel, E Yeger-Lotem Nucleic acids research 39 (suppl_2), W424-W429, 2011 | 85 | 2011 |