Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3516 | 2010 |
Use of colonoscopy to screen asymptomatic adults for colorectal cancer DA Lieberman, DG Weiss, JH Bond, DJ Ahnen, H Garewal, WV Harford, ... New England Journal of Medicine 343 (3), 162-168, 2000 | 2339 | 2000 |
Targeting antioxidants to mitochondria by conjugation to lipophilic cations MP Murphy, RAJ Smith Annu. Rev. Pharmacol. Toxicol. 47, 629-656, 2007 | 1292 | 2007 |
Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties GF Kelso, CM Porteous, CV Coulter, G Hughes, WK Porteous, ... Journal of Biological Chemistry 276 (7), 4588-4596, 2001 | 1288 | 2001 |
Carotid endarterectomy and prevention of cerebral ischemia in symptomatic carotid stenosis MR Mayberg, SE Wilson, F Yatsu, DG Weiss, L Messina, LA Hershey, ... Jama 266 (23), 3289-3294, 1991 | 1206 | 1991 |
American Cancer Society guidelines for the early detection of cancer: update of early detection guidelines for prostate, colorectal, and endometrial cancers: Also: update 2001 … RA Smith, AC von Eschenbach, R Wender, B Levin, T Byers, ... CA: a cancer journal for clinicians 51 (1), 38-75, 2001 | 1066 | 2001 |
One-time screening for colorectal cancer with combined fecal occult-blood testing and examination of the distal colon DA Lieberman, WV Harford, DJ Ahnen, D Provenzale, SJ Sontag, ... New England Journal of Medicine 345 (8), 555-560, 2001 | 824 | 2001 |
Delivery of bioactive molecules to mitochondria in vivo RAJ Smith, CM Porteous, AM Gane, MP Murphy Proceedings of the National Academy of Sciences 100 (9), 5407-5412, 2003 | 820 | 2003 |
Targeting an antioxidant to mitochondria decreases cardiac ischemia‐reperfusion injury VJ Adlam, JC Harrison, CM Porteous, AM James, RAJ Smith, MP Murphy, ... The FASEB Journal 19 (9), 1088-1095, 2005 | 715 | 2005 |
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I ET Chouchani, C Methner, SM Nadtochiy, A Logan, VR Pell, S Ding, ... Nature medicine 19 (6), 753-759, 2013 | 651 | 2013 |
Selective targeting of an antioxidant to mitochondria RAJ Smith, CM Porteous, CV Coulter, MP Murphy European Journal of Biochemistry 263 (3), 709-716, 1999 | 587 | 1999 |
A double‐blind, placebo‐controlled study to assess the mitochondria‐targeted antioxidant MitoQ as a disease‐modifying therapy in Parkinson's disease BJ Snow, FL Rolfe, MM Lockhart, CM Frampton, JD O'Sullivan, V Fung, ... Movement Disorders 25 (11), 1670-1674, 2010 | 580 | 2010 |
Animal and human studies with the mitochondria‐targeted antioxidant MitoQ RAJ Smith, MP Murphy Annals of the new York Academy of Sciences 1201 (1), 96-103, 2010 | 577 | 2010 |
Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology MF Ross, GF Kelso, FH Blaikie, AM James, HM Cocheme, A Filipovska, ... Biochemistry (Moscow) 70, 222-230, 2005 | 559 | 2005 |
Mitochondrial pharmacology RAJ Smith, RC Hartley, HM Cocheme, MP Murphy Trends in pharmacological sciences 33 (6), 341-352, 2012 | 544 | 2012 |
Superoxide activates mitochondrial uncoupling protein 2 from the matrix side: studies using targeted antioxidants KS Echtay, MP Murphy, RAJ Smith, DA Talbot, MD Brand Journal of Biological Chemistry 277 (49), 47129-47135, 2002 | 511 | 2002 |
Drug delivery to mitochondria: the key to mitochondrial medicine MP Murphy, RAJ Smith Advanced drug delivery reviews 41 (2), 235-250, 2000 | 511 | 2000 |
Ferredoxin reductase affects p53-dependent, 5-fluorouracil–induced apoptosis in colorectal cancer cells PM Hwang, F Bunz, J Yu, C Rago, TA Chan, MP Murphy, GF Kelso, ... Nature medicine 7 (10), 1111-1117, 2001 | 479 | 2001 |
Interactions of Mitochondria-targeted and Untargeted Ubiquinones with the Mitochondrial Respiratory Chain and Reactive Oxygen Species: IMPLICATIONS FOR THE USE OF EXOGENOUS … AM James, HM Cochemé, RAJ Smith, MP Murphy Journal of Biological Chemistry 280 (22), 21295-21312, 2005 | 456 | 2005 |
Mitochondria‐targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants ML Jauslin, T Meier, RAJ Smith, PM Murphy The FASEB journal 17 (13), 1-10, 2003 | 452 | 2003 |