Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis SJ Dixon, DN Patel, M Welsch, R Skouta, ED Lee, M Hayano, AG Thomas, ... elife 3, e02523, 2014 | 1635 | 2014 |
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells A Le, AN Lane, M Hamaker, S Bose, A Gouw, J Barbi, T Tsukamoto, ... Cell metabolism 15 (1), 110-121, 2012 | 1185 | 2012 |
HIV-associated neurocognitive disorder—pathogenesis and prospects for treatment D Saylor, AM Dickens, N Sacktor, N Haughey, B Slusher, M Pletnikov, ... Nature Reviews Neurology 12 (4), 234-248, 2016 | 1032 | 2016 |
Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion RD Leone, L Zhao, JM Englert, IM Sun, MH Oh, IH Sun, ML Arwood, ... Science 366 (6468), 1013-1021, 2019 | 776 | 2019 |
Abnormal excitatory neurotransmitter metabolism in schizophrenic brains G Tsai, LA Passani, BS Slusher, R Carter, L Baer, JE Kleinman, JT Coyle Archives of general psychiatry 52 (10), 829-836, 1995 | 618 | 1995 |
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1 MJ Seltzer, BD Bennett, AD Joshi, P Gao, AG Thomas, DV Ferraris, ... Cancer research 70 (22), 8981-8987, 2010 | 586 | 2010 |
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis Y Xiang, ZE Stine, J Xia, Y Lu, RS O’Connor, BJ Altman, AL Hsieh, ... The Journal of clinical investigation 125 (6), 2293-2306, 2015 | 456 | 2015 |
Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury BS Slusher, JJ Vornov, AG Thomas, PD Hurn, I Harukuni, A Bhardwaj, ... Nature medicine 5 (12), 1396-1402, 1999 | 369 | 1999 |
Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated α-linked acidic dipeptidase PF Jackson, DC Cole, BS Slusher, SL Stetz, LE Ross, BA Donzanti, ... Journal of medicinal chemistry 39 (2), 619-622, 1996 | 364 | 1996 |
Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer JR Mesters, C Barinka, W Li, T Tsukamoto, P Majer, BS Slusher, ... The EMBO journal 25 (6), 1375-1384, 2006 | 339 | 2006 |
Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic … SY Cho, KL Gage, RC Mease, S Senthamizhchelvan, DP Holt, ... Journal of Nuclear Medicine 53 (12), 1883-1891, 2012 | 333 | 2012 |
Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor C Rojas, M Stathis, AG Thomas, EB Massuda, J Alt, J Zhang, ... Anesthesia & Analgesia 107 (2), 469-478, 2008 | 288 | 2008 |
Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells MH Oh, IH Sun, L Zhao, RD Leone, IM Sun, W Xu, SL Collins, AJ Tam, ... The Journal of clinical investigation 130 (7), 3865-3884, 2020 | 267 | 2020 |
Glutamate carboxypeptidase II in diagnosis and treatment of neurologic disorders and prostate cancer C Barinka, C Rojas, B Slusher, M Pomper Current medicinal chemistry 19 (6), 856-870, 2012 | 247 | 2012 |
Palonosetron triggers 5-HT3 receptor internalization and causes prolonged inhibition of receptor function C Rojas, AG Thomas, J Alt, M Stathis, J Zhang, EB Rubenstein, ... European journal of pharmacology 626 (2-3), 193-199, 2010 | 232 | 2010 |
Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1, 2, 4-thiadiazol-2-yl) ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors K Shukla, DV Ferraris, AG Thomas, M Stathis, B Duvall, G Delahanty, J Alt, ... Journal of medicinal chemistry 55 (23), 10551-10563, 2012 | 231 | 2012 |
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer A Elgogary, Q Xu, B Poore, J Alt, SC Zimmermann, L Zhao, J Fu, B Chen, ... Proceedings of the National Academy of Sciences 113 (36), E5328-E5336, 2016 | 224 | 2016 |
Preventing allograft rejection by targeting immune metabolism CF Lee, YC Lo, CH Cheng, GJ Furtmüller, B Oh, V Andrade-Oliveira, ... Cell reports 13 (4), 760-770, 2015 | 193 | 2015 |
In vitro and in vivo radiosensitization of glioblastoma cells by the poly (ADP-ribose) polymerase inhibitor E7016 AL Russo, HC Kwon, WE Burgan, D Carter, K Beam, X Weizheng, ... Clinical Cancer Research 15 (2), 607-612, 2009 | 189 | 2009 |
Rat brain N-acetylated alpha-linked acidic dipeptidase activity. Purification and immunologic characterization. BS Slusher, MB Robinson, G Tsai, ML Simmons, SS Richards, JT Coyle Journal of Biological Chemistry 265 (34), 21297-21301, 1990 | 188 | 1990 |