| Challenges and opportunities in enterprise-wide optimization in the pharmaceutical industry JM Laínez, E Schaefer, GV Reklaitis Computers & Chemical Engineering 47, 19-28, 2012 | 153 | 2012 |
| Characterization of replication-competent adenovirus isolates from large-scale production of a recombinant adenoviral vector J Zhu, M Grace, J Casale, R Bordens, R Greenberg, E Schaefer, ... Human gene therapy 10 (1), 113-121, 1999 | 125 | 1999 |
| Development and improvement of a serum-free suspension process for the production of recombinant adenoviral vectors using HEK293 cells YS Tsao, R Condon, E Schaefer, P Lio, Z Liu Cytotechnology 37, 189-198, 2001 | 49 | 2001 |
| Carbohydrate content of CTLA4 molecules KJ Leister, EJ Schaefer, RC Bates, EA Bramhall, DM Didio, R Donaldson, ... US Patent 10,508,144, 2019 | 28 | 2019 |
| Direct monitoring of the liquid and gas phases during a fermentation in a computer-mass-spectrometer-fermentor system E Pungor, EJ Schaefer, CL Cooney, JC Weaver European journal of applied microbiology and biotechnology 18, 135-140, 1983 | 28 | 1983 |
| Manufacturing methods to control C-terminal lysine, galactose and sialic acid content in recombinant proteins M Flikweert, C Goochee, F Maslanka, FJI Nagel, J Ryland, E Schaefer US Patent App. 14/207,915, 2014 | 21 | 2014 |
| Development of a Chinese hamster ovary cell line for recombinant adenovirus‐mediated gene expression RGG Condon, EJ Schaefer, M Santoro, R Longley Jr, YS Tsao, ... Biotechnology progress 19 (1), 137-143, 2003 | 21 | 2003 |
| Optimizing performance of semi‐continuous cell culture in an ambr15™ microbioreactor using dynamic flux balance modeling W Kelly, S Veigne, X Li, SS Subramanian, Z Huang, E Schaefer Biotechnology progress 34 (2), 420-431, 2018 | 17 | 2018 |
| Role of integrin αVβ3 in the production of recombinant adenoviruses in HEK-293 cells WLW Ling, RL Longley, DL Brassard, L Armstrong, EJ Schaefer Gene therapy 9 (14), 907-914, 2002 | 16 | 2002 |
| Direct monitoring of a fermentation in a computer-mass spectrometer-fermentor system E Pungor Jr, E Schaefer, JC Weaver, CL Cooney Scientific and Engineering Principles, 393-398, 1981 | 15 | 1981 |
| Production of maltase by wild-type and a constitutive mutant of Saccharomyces italicus EJ Schaefer, CL Cooney Applied and environmental microbiology 43 (1), 75-80, 1982 | 14 | 1982 |
| Manufacturing methods to control C-terminal lysine, galactose and sialic acid content in recombinant proteins M Flikweert, C Goochee, FC Maslanka, FJI Nagel, JR Ryland, E Schaefer US Patent 11,149,085, 2021 | 13 | 2021 |
| Biomass and aggregation analysis of human embryonic kidney 293 suspension cell cultures by particle size measurement YS Tsao, RGG Condon, EJ Schaefer, DA Lindsay, Z Liu Biotechnology progress 16 (5), 809-814, 2000 | 11 | 2000 |
| Microarray platform affords improved product analysis in mammalian cell growth studies P Datta, L Meli, L Li, N Migliore, E Schaefer, ST Sharfstein, JS Dordick, ... Biotechnology journal 9 (3), 386-395, 2014 | 9 | 2014 |
| Effect of pressure on an aminoglycoside fermentation mediated by dissolved oxygen V Yabannavar, V Singh, E Schaefer Journal of fermentation and bioengineering 73 (1), 66-69, 1992 | 5 | 1992 |
| Compositions and methods for producing a composition KJ Leister, EJ Schaefer, RC Bates, EA Bramhall, DM Didio, R Donaldson, ... US Patent 10,808,021, 2020 | 4 | 2020 |
| Process for producing maltase CL Cooney, EJ Schaefer US Patent 4,332,899, 1982 | 4 | 1982 |
| Carbohydrate content of CTLA4 molecules KJ Leister, EJ Schaefer, RC Bates, EA Bramhall, DM Didio, R Donaldson, ... US Patent 10,941,189, 2021 | 3 | 2021 |
| Process for production of improved maltase CL Cooney, EJ Schaefer US Patent 4,395,490, 1983 | 2 | 1983 |
| Compositions and methods for producing a composition KJ Leister, EJ Schaefer, RC Bates, EA Bramhall, DM Didio, R Donaldson, ... US Patent App. 17/105,358, 2021 | | 2021 |
