New tricks for the glycyl radical enzyme family LRF Backman, MA Funk, CD Dawson, CL Drennan Critical reviews in biochemistry and molecular biology 52 (6), 674-695, 2017 | 83 | 2017 |
Oxidative stress shapes breast cancer phenotype through chronic activation of ATM-dependent signaling M Alpay, LRF Backman, X Cheng, M Dukel, WJ Kim, L Ai, KD Brown Breast cancer research and treatment 151, 75-87, 2015 | 45 | 2015 |
The breast cancer tumor suppressor TRIM29 is expressed via ATM-dependent signaling in response to hypoxia M Dükel, WS Streitfeld, TCC Tang, LRF Backman, L Ai, WS May, ... Journal of Biological Chemistry 291 (41), 21541-21552, 2016 | 31 | 2016 |
Molecular basis for catabolism of the abundant metabolite trans-4-hydroxy-L-proline by a microbial glycyl radical enzyme LRF Backman, YY Huang, MC Andorfer, B Gold, RT Raines, EP Balskus, ... elife 9, e51420, 2020 | 17 | 2020 |
Molecular basis of CS bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase CD Dawson, SM Irwin, LRF Backman, C Le, JX Wang, V Vennelakanti, ... Cell Chemical Biology 28 (9), 1333-1346. e7, 2021 | 16 | 2021 |
Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme SEJ Bowman, LRF Backman, RE Bjork, MC Andorfer, S Yori, A Caruso, ... JBIC Journal of Biological Inorganic Chemistry 24, 817-829, 2019 | 14 | 2019 |
Rescuing activity of oxygen-damaged pyruvate formate-lyase by a spare part protein MC Andorfer, LRF Backman, PL Li, EC Ulrich, CL Drennan Journal of Biological Chemistry 297 (6), 2021 | 8 | 2021 |
ATM is required for SOD2 expression and homeostasis within the mammary gland LM Dyer, JD Kepple, L Ai, WJ Kim, VL Stanton, MK Reinhard, ... Breast cancer research and treatment 166, 725-741, 2017 | 7 | 2017 |
Abstract 1847 Capturing multiple conformations of glycyl radical enzymes found in the human gut microbiome using single particle cryoEM C Imrich, L Backman, M Andorfer, C Drennan Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Abstract 1963 Bacterial Organelles: Encapsulation of Anaerobic Metabolic Pathways within Bacterial Microcompartments in the Human Microbiome L Backman Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Track: Miniproteins: Are There Really That Many Additional Genes That We Have Been Missing? Is it a mistake in the genome sequencing or a spare part protein? M Andorfer, L Backman PROTEIN SCIENCE 32, 2023 | | 2023 |
Structurally investigating a niche pathway for chemical reversal of proline hydroxylation in the pathogen Clostridioides difficile LRF Backman, YY Huang, MC Andorfer, B Gold, RT Raines, EP Balskus, ... The FASEB Journal 36, 2022 | | 2022 |
Repairing enzymes using spare parts CL Drennan, MC Andorfer, LRF Backman, PL Li, EC Ulrich The FASEB Journal 36, 2022 | | 2022 |
Structural and Biochemical Characterization of Glycyl Radical Enzymes Abundant in Mammalian Gut Microbiota LRF Backman Massachusetts Institute of Technology, 2022 | | 2022 |
Spare Parts for Oxygen-Damaged Enzymes M Andorfer, L Backman, S Bowman, R Bjork, E Ulrich, P Li, S Yori, ... PROTEIN SCIENCE 30, 31-31, 2021 | | 2021 |
Structurally investigating a niche pathway for chemical reversal of proline hydroxylation in the pathogen C. difficile L Backman Acta Crystallographica Section A: Foundations and Advances 77, a4-a4, 2021 | | 2021 |
Molecular basis for catabolism of the abundant metabolite trans-4-hydroxy-L-proline by a LR Backman, YY Huang, MC Andorfer | | 2020 |
Mechanistic study of glycyl radical enzyme Z Yang, H Kulik 2019 AIChE Annual Meeting, 2019 | | 2019 |
Restoring activity to oxygen-damaged glycyl radical enzymes: Spare parts for proteins M Andorfer, L Backman, S Bowman, R Bjork, P Li, S Yori, C Drennan ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
Anaerobic 4‐Hydroxyproline Metabolism by a Widespread Microbial Glycyl Radical Enzyme YY Huang, L Backman, B Gold, RT Raines, CL Drennan, EP Balskus The FASEB Journal 32, 534.16-534.16, 2018 | | 2018 |