HIF-1α is essential for myeloid cell-mediated inflammation T Cramer, Y Yamanishi, BE Clausen, I Förster, R Pawlinski, N Mackman, ... Cell 112 (5), 645-657, 2003 | 2441 | 2003 |
Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor α expression by inducing Elk-1 phosphorylation … M Guha, MA O'Connell, R Pawlinski, A Hollis, P McGovern, SF Yan, ... Blood, The Journal of the American Society of Hematology 98 (5), 1429-1439, 2001 | 472 | 2001 |
Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia R Pawlinski, B Pedersen, G Schabbauer, M Tencati, T Holscher, ... Blood 103 (4), 1342-1347, 2004 | 363 | 2004 |
Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation F Niessen, F Schaffner, C Furlan-Freguia, R Pawlinski, G Bhattacharjee, ... Nature 452 (7187), 654-658, 2008 | 349 | 2008 |
The thrombomodulin–protein C system is essential for the maintenance of pregnancy B Isermann, R Sood, R Pawlinski, M Zogg, S Kalloway, JL Degen, ... Nature medicine 9 (3), 331-337, 2003 | 329 | 2003 |
Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages JP Luyendyk, GA Schabbauer, M Tencati, T Holscher, R Pawlinski, ... The Journal of Immunology 180 (6), 4218-4226, 2008 | 292 | 2008 |
PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice G Schabbauer, M Tencati, B Pedersen, R Pawlinski, N Mackman Arteriosclerosis, thrombosis, and vascular biology 24 (10), 1963-1969, 2004 | 285 | 2004 |
In vitro activation of coagulation by human neutrophil DNA and histone proteins but not neutrophil extracellular traps DF Noubouossie, MF Whelihan, YB Yu, E Sparkenbaugh, R Pawlinski, ... Blood, The Journal of the American Society of Hematology 129 (8), 1021-1029, 2017 | 236 | 2017 |
Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer JG Wang, JE Geddings, MM Aleman, JC Cardenas, ... Blood, The Journal of the American Society of Hematology 119 (23), 5543-5552, 2012 | 229 | 2012 |
Homogeneous low-molecular-weight heparins with reversible anticoagulant activity Y Xu, C Cai, K Chandarajoti, PH Hsieh, L Li, TQ Pham, EM Sparkenbaugh, ... Nature chemical biology 10 (4), 248-250, 2014 | 214 | 2014 |
Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic mice R Pawlinski, JG Wang, AP Owens III, J Williams, S Antoniak, M Tencati, ... Blood, The Journal of the American Society of Hematology 116 (5), 806-814, 2010 | 193 | 2010 |
Interplay between coagulation and vascular inflammation in sickle cell disease E Sparkenbaugh, R Pawlinski British Journal of Haematology 162 (1), 3-14, 2013 | 188 | 2013 |
Cellular sources of tissue factor in endotoxemia and sepsis R Pawlinski, N Mackman Thrombosis research 125, S70-S73, 2010 | 181 | 2010 |
Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy R Pawlinski, M Tencati, CR Hampton, T Shishido, TA Bullard, LM Casey, ... Circulation 116 (20), 2298-2306, 2007 | 167 | 2007 |
PAR-1 contributes to the innate immune response during viral infection S Antoniak, AP Owens, M Baunacke, JC Williams, RD Lee, A Weithäuser, ... The Journal of clinical investigation 123 (3), 1310-1322, 2013 | 157 | 2013 |
Levels of microparticle tissue factor activity correlate with coagulation activation in endotoxemic mice JG Wang, D Manly, D Kirchhofer, R Pawlinski, N Mackman Journal of Thrombosis and Haemostasis 7 (7), 1092-1098, 2009 | 154 | 2009 |
Tissue factor, coagulation proteases, and protease-activated receptors in endotoxemia and sepsis R Pawlinski, N Mackman Critical care medicine 32 (5), S293-S297, 2004 | 152 | 2004 |
Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease EM Sparkenbaugh, P Chantrathammachart, J Mickelson, J Van Ryn, ... Blood, The Journal of the American Society of Hematology 123 (11), 1747-1756, 2014 | 128 | 2014 |
Elevated hematocrit enhances platelet accumulation following vascular injury BL Walton, M Lehmann, T Skorczewski, LA Holle, JD Beckman, JA Cribb, ... Blood, The Journal of the American Society of Hematology 129 (18), 2537-2546, 2017 | 127 | 2017 |
A balance between tissue factor and tissue factor pathway inhibitor is required for embryonic development and hemostasis in adult mice B Pedersen, T Holscher, Y Sato, R Pawlinski, N Mackman Blood 105 (7), 2777-2782, 2005 | 125 | 2005 |