Diabetes induces aberrant DNA methylation in the proximal tubules of the kidney T Marumo, S Yagi, W Kawarazaki, M Nishimoto, N Ayuzawa, A Watanabe, ... Journal of the American Society of Nephrology 26 (10), 2388-2397, 2015 | 107 | 2015 |
Rac1-mediated activation of mineralocorticoid receptor in pressure overload–induced cardiac injury N Ayuzawa, M Nagase, K Ueda, M Nishimoto, W Kawarazaki, T Marumo, ... Hypertension 67 (1), 99-106, 2016 | 67 | 2016 |
Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency W Kawarazaki, R Mizuno, M Nishimoto, N Ayuzawa, D Hirohama, K Ueda, ... The Journal of Clinical Investigation 130 (8), 4152-4166, 2020 | 57 | 2020 |
Renal mechanisms of salt-sensitive hypertension: contribution of two steroid receptor-associated pathways M Nishimoto, T Fujita American Journal of Physiology-Renal Physiology 308 (5), F377-F387, 2015 | 48 | 2015 |
Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension F Kawakami-Mori, M Nishimoto, L Reheman, W Kawarazaki, N Ayuzawa, ... JCI insight 3 (21), 2018 | 34 | 2018 |
Aldosterone is essential for angiotensin II-induced upregulation of pendrin D Hirohama, N Ayuzawa, K Ueda, M Nishimoto, W Kawarazaki, ... Journal of the American Society of Nephrology 29 (1), 57-68, 2018 | 34 | 2018 |
Renal Dysfunction Induced by Kidney-Specific Gene Deletion of Hsd11b2 as a Primary Cause of Salt-Dependent Hypertension K Ueda, M Nishimoto, D Hirohama, N Ayuzawa, W Kawarazaki, ... Hypertension 70 (1), 111-118, 2017 | 34 | 2017 |
Activation of Rac1-Mineralocorticoid Receptor Pathway Contributes to Renal Injury in Salt-Loaded db/db Mice D Hirohama, M Nishimoto, N Ayuzawa, W Kawarazaki, W Fujii, S Oba, ... Hypertension 78 (1), 82-93, 2021 | 28 | 2021 |
Mineralocorticoid receptor blockade suppresses dietary salt-induced ACEI/ARB-resistant albuminuria in non-diabetic hypertension: a sub-analysis of evaluate study M Nishimoto, H Ohtsu, T Marumo, W Kawarazaki, N Ayuzawa, K Ueda, ... Hypertension Research 42 (4), 514-521, 2019 | 26 | 2019 |
Two Mineralocorticoid Receptor–Mediated Mechanisms of Pendrin Activation in Distal Nephrons N Ayuzawa, M Nishimoto, K Ueda, D Hirohama, W Kawarazaki, ... Journal of the American Society of Nephrology 31 (4), 748-764, 2020 | 25 | 2020 |
Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells S Oba, N Ayuzawa, M Nishimoto, W Kawarazaki, K Ueda, D Hirohama, ... Scientific reports 8 (1), 16338, 2018 | 22 | 2018 |
Methylation pattern of urinary DNA as a marker of kidney function decline in diabetes T Marumo, J Hoshino, W Kawarazaki, M Nishimoto, N Ayuzawa, ... BMJ Open Diabetes Research and Care 8 (1), e001501, 2020 | 18 | 2020 |
A high-salt diet differentially modulates mechanical activity of afferent and efferent collecting lymphatics in murine iliac lymph nodes R Mizuno, M Isshiki, N Ono, M Nishimoto, T Fujita Lymphatic research and biology 13 (2), 85-92, 2015 | 18 | 2015 |
Aberrant DNA methylation of pregnane X receptor underlies metabolic gene alterations in the diabetic kidney A Watanabe, T Marumo, W Kawarazaki, M Nishimoto, N Ayuzawa, ... American Journal of Physiology-Renal Physiology 314 (4), F551-F560, 2018 | 17 | 2018 |
Stromal interaction molecule 1 modulates blood pressure via NO production in vascular endothelial cells M Nishimoto, R Mizuno, T Fujita, M Isshiki Hypertension Research 41 (7), 506-514, 2018 | 14 | 2018 |
Synthesis of the C70 Fragment Buckybowl, Homosumanene, and Heterahomosumanenes via Ring-Expansion Reactions from Sumanenone M Nishimoto, Y Uetake, Y Yakiyama, F Ishiwari, A Saeki, H Sakurai The Journal of Organic Chemistry 87 (5), 2508-2519, 2022 | 13 | 2022 |
FRET-based sensor analysis reveals caveolae are spatially distinct Ca2+ stores in endothelial cells M Isshiki, M Nishimoto, R Mizuno, T Fujita Cell calcium 54 (6), 395-403, 2013 | 13 | 2013 |
A high salt diet alters pressure-induced mechanical activity of the rat lymphatics with enhancement of myogenic characteristics R Mizuno, M Isshiki, N Ono, M Nishimoto, T Fujita Lymphatic Research and Biology 13 (1), 2-9, 2015 | 12 | 2015 |
PGI2 Analog Attenuates Salt-Induced Renal Injury through the Inhibition of Inflammation and Rac1-MR Activation D Hirohama, W Kawarazaki, M Nishimoto, N Ayuzawa, T Marumo, ... International journal of molecular sciences 21 (12), 4433, 2020 | 11 | 2020 |
Clinical effect of nonsteroidal mineralocorticoid receptor (MR) antagonists in the treatment of diabetic kidney disease: expectations as a new therapeutic strategy A Sato, M Nishimoto Hypertension Research 45 (8), 1310-1321, 2022 | 4 | 2022 |