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Leigh C Walker
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Anterior insular cortex is critical for the propensity to relapse following punishment-imposed abstinence of alcohol seeking
EJ Campbell, JPM Flanagan, LC Walker, MKRI Hill, NJ Marchant, ...
Journal of Neuroscience 39 (6), 1077-1087, 2019
732019
Pharmacology and anti‐addiction effects of the novel κ opioid receptor agonist M esyl S al B, a potent and long‐acting analogue of salvinorin A
B Simonson, AS Morani, AWM Ewald, L Walker, N Kumar, D Simpson, ...
British journal of pharmacology 172 (2), 515-531, 2015
732015
Nucleus incertus Orexin2 receptors mediate alcohol seeking in rats
HE Kastman, A Blasiak, L Walker, M Siwiec, EV Krstew, AL Gundlach, ...
Neuropharmacology 110, 82-91, 2016
472016
The role of orexins/hypocretins in alcohol use and abuse
LC Walker, AJ Lawrence
Behavioral Neuroscience of Orexin/Hypocretin, 221-246, 2017
452017
The effect of acute or repeated stress on the corticotropin releasing factor system in the CRH-IRES-Cre mouse: a validation study
LC Walker, LC Cornish, AJ Lawrence, EJ Campbell
Neuropharmacology 154, 96-106, 2019
382019
Nucleus incertus corticotrophin‐releasing factor 1 receptor signalling regulates alcohol seeking in rats
LC Walker, HE Kastman, JA Koeleman, CM Smith, CJ Perry, EV Krstew, ...
Addiction Biology 22 (6), 1641-1654, 2017
362017
Acetylcholine muscarinic M4 receptors as a therapeutic target for alcohol use disorder: converging evidence from humans and rodents
LC Walker, AE Berizzi, NA Chen, P Rueda, VM Perreau, K Huckstep, ...
Biological Psychiatry 88 (12), 898-909, 2020
352020
Central amygdala relaxin‐3/relaxin family peptide receptor 3 signalling modulates alcohol seeking in rats
LC Walker, HE Kastman, EV Krstew, AL Gundlach, AJ Lawrence
British journal of pharmacology 174 (19), 3359-3369, 2017
302017
A balancing act: The role of pro‐and anti‐stress peptides within the central amygdala in anxiety and alcohol use disorders
LC Walker
Journal of neurochemistry 157 (5), 1615-1643, 2021
252021
Cocaine and amphetamine regulated transcript (CART) signalling in the central nucleus of the amygdala modulates stress-induced alcohol seeking
LC Walker, LJ Hand, B Letherby, KL Huckstep, EJ Campbell, ...
Neuropsychopharmacology 46 (2), 325-333, 2021
192021
Investigational drug therapies in phase I and phase II clinical trials for alcohol use disorders
LC Walker, AJ Lawrence
Expert Opinion on Investigational Drugs 27 (8), 677-690, 2018
172018
Allosteric modulation of muscarinic receptors in alcohol and substance use disorders
LC Walker, AJ Lawrence
Advances in Pharmacology 88, 233-275, 2020
132020
Muscarinic M4 and M5 receptors in the ventral subiculum differentially modulate alcohol seeking versus consumption in male alcohol‐preferring rats
LC Walker, KL Huckstep, NA Chen, LJ Hand, CW Lindsley, CJ Langmead, ...
British journal of pharmacology 178 (18), 3730-3746, 2021
122021
Pattern of neural activation following yohimbine‐induced reinstatement of alcohol seeking in rats
LC Walker, HE Kastman, AJ Lawrence
European Journal of Neuroscience 51 (3), 706-720, 2020
122020
M1 muscarinic receptor activation decreases alcohol consumption via a reduction in consummatory behavior
LC Walker, EJ Campbell, KL Huckstep, NA Chen, CJ Langmead, ...
Pharmacology Research & Perspectives 10 (1), e00907, 2022
102022
Gray areas: Neuropeptide circuits linking the Edinger-Westphal and Dorsal Raphe nuclei in addiction
MB Pomrenze, LC Walker, WJ Giardino
Neuropharmacology 198, 108769, 2021
102021
Clinical effectiveness of muscarinic receptor-targeted interventions in neuropsychiatric disorders: A systematic review
S Vaidya, AA Guerin, LC Walker, AJ Lawrence
CNS drugs 36 (11), 1171-1206, 2022
82022
Targeting muscarinic receptors for the treatment of alcohol use disorders: Opportunities and hurdles for clinical development
LC Walker, KL Huckstep, HC Becker, CJ Langmead, AJ Lawrence
British Journal of Pharmacology, 2023
72023
Role of lateral hypothalamic orexin (hypocretin) neurons in alcohol use and abuse: recent advances
LC Walker, SS Ch’ng, AJ Lawrence
Current Pharmacology Reports 2, 241-252, 2016
62016
Organisation of enkephalin inputs and outputs of the central nucleus of the amygdala in mice
A Viden, SS Ch’ng, LC Walker, A Shesham, SM Hamilton, CM Smith, ...
Journal of Chemical Neuroanatomy 125, 102167, 2022
52022
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