HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA TL Roberts, A Idris, JA Dunn, GM Kelly, CM Burnton, S Hodgson, ... Science 323 (5917), 1057-1060, 2009 | 996 | 2009 |
AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC V Sagulenko, SJ Thygesen, DP Sester, A Idris, JA Cridland, PR Vajjhala, ... Cell Death & Differentiation 20 (9), 1149-1160, 2013 | 507 | 2013 |
The molecular basis for the lack of immunostimulatory activity of vertebrate DNA KJ Stacey, GR Young, F Clark, DP Sester, TL Roberts, S Naik, MJ Sweet, ... The Journal of Immunology 170 (7), 3614-3620, 2003 | 233 | 2003 |
The mammalian PYHIN gene family: phylogeny, evolution and expression JA Cridland, EZ Curley, MN Wykes, K Schroder, MJ Sweet, TL Roberts, ... BMC evolutionary biology 12, 1-17, 2012 | 223 | 2012 |
Cutting edge: species-specific TLR9-mediated recognition of CpG and non-CpG phosphorothioate-modified oligonucleotides TL Roberts, MJ Sweet, DA Hume, KJ Stacey The Journal of Immunology 174 (2), 605-608, 2005 | 178 | 2005 |
A role for homologous recombination and abnormal cell-cycle progression in radioresistance of glioma-initiating cells YC Lim, TL Roberts, BW Day, A Harding, S Kozlov, AW Kijas, KS Ensbey, ... Molecular cancer therapeutics 11 (9), 1863-1872, 2012 | 111 | 2012 |
Endoplasmic reticulum stress in the development of multiple myeloma and drug resistance N Nikesitch, JM Lee, S Ling, TL Roberts Clinical & translational immunology 7 (1), e1007, 2018 | 100 | 2018 |
Differences in macrophage activation by bacterial DNA and CpG-containing oligonucleotides TL Roberts, JA Dunn, TD Terry, MP Jennings, DA Hume, MJ Sweet, ... The Journal of Immunology 175 (6), 3569-3576, 2005 | 89 | 2005 |
Increased sensitivity to ionizing radiation by targeting the homologous recombination pathway in glioma initiating cells YC Lim, TL Roberts, BW Day, BW Stringer, S Kozlov, S Fazry, ZC Bruce, ... Molecular oncology 8 (8), 1603-1615, 2014 | 85 | 2014 |
A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype H Quek, J Luff, KG Cheung, S Kozlov, M Gatei, CS Lee, MC Bellingham, ... Human molecular genetics 26 (1), 109-123, 2017 | 80 | 2017 |
CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway DP Sester, K Brion, A Trieu, HS Goodridge, TL Roberts, J Dunn, DA Hume, ... The Journal of Immunology 177 (7), 4473-4480, 2006 | 79 | 2006 |
A novel role for hSMG-1 in stress granule formation JAL Brown, TL Roberts, R Richards, R Woods, G Birrell, YC Lim, S Ohno, ... Molecular and cellular biology 31 (22), 4417-4429, 2011 | 65 | 2011 |
Smg1 haploinsufficiency predisposes to tumor formation and inflammation TL Roberts, U Ho, J Luff, CS Lee, SH Apte, KPA MacDonald, LJ Raggat, ... Proceedings of the National Academy of Sciences 110 (4), E285-E294, 2013 | 63 | 2013 |
DNA motifs suppressing TLR9 responses A Trieu, TL Roberts, JA Dunn, MJ Sweet, KJ Stacey Critical Reviews™ in Immunology 26 (6), 2006 | 58 | 2006 |
ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression H Quek, C Cuní-López, R Stewart, T Colletti, A Notaro, TH Nguyen, Y Sun, ... Journal of Neuroinflammation 19 (1), 58, 2022 | 57 | 2022 |
Plasma next generation sequencing and droplet digital PCR‐based detection of epidermal growth factor receptor (EGFR) mutations in patients with advanced lung cancer treated … PN Ding, T Becker, V Bray, W Chua, Y Ma, B Xu, D Lynch, P de Souza, ... Thoracic cancer 10 (10), 1879-1884, 2019 | 47 | 2019 |
Molecular biomarkers in glioblastoma: A systematic review and meta-analysis H Sareen, Y Ma, TM Becker, TL Roberts, P de Souza, B Powter International journal of molecular sciences 23 (16), 8835, 2022 | 46 | 2022 |
Molecular interactions of polo-like kinase 1 in human cancers WTW Ng, JS Shin, TL Roberts, B Wang, CS Lee Journal of Clinical Pathology 69 (7), 557-562, 2016 | 46 | 2016 |
The genomic landscape of thyroid cancer tumourigenesis and implications for immunotherapy A Singh, J Ham, JW Po, N Niles, T Roberts, CS Lee Cells 10 (5), 1082, 2021 | 45 | 2021 |
Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage H Quek, J Luff, KG Cheung, S Kozlov, M Gatei, CS Lee, MC Bellingham, ... Journal of Leucocyte Biology 101 (4), 927-947, 2017 | 43 | 2017 |