Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum SC Bendall, EF Simonds, P Qiu, DA El-ad, PO Krutzik, R Finck, ... Science 332 (6030), 687-696, 2011 | 2450 | 2011 |
Data-driven phenotypic dissection of AML reveals progenitor-like cells that correlate with prognosis JH Levine, EF Simonds, SC Bendall, KL Davis, DA El-ad, MD Tadmor, ... Cell 162 (1), 184-197, 2015 | 2019 | 2015 |
viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia ED Amir, KL Davis, MD Tadmor, EF Simonds, JH Levine, SC Bendall, ... Nature biotechnology 31 (6), 545-552, 2013 | 1590 | 2013 |
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE P Qiu, EF Simonds, SC Bendall, KD Gibbs Jr, RV Bruggner, ... Nature biotechnology 29 (10), 886-891, 2011 | 1055 | 2011 |
Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development SC Bendall, KL Davis, ED Amir, MD Tadmor, EF Simonds, TJ Chen, ... Cell 157 (3), 714-725, 2014 | 968 | 2014 |
Normalization of mass cytometry data with bead standards R Finck, EF Simonds, A Jager, S Krishnaswamy, K Sachs, W Fantl, ... Cytometry Part A 83 (5), 483-494, 2013 | 717 | 2013 |
Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators B Bodenmiller, ER Zunder, R Finck, TJ Chen, ES Savig, RV Bruggner, ... Nature biotechnology 30 (9), 858-867, 2012 | 593 | 2012 |
Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms ST Oh, EF Simonds, C Jones, MB Hale, Y Goltsev, KD Gibbs Jr, ... Blood, The Journal of the American Society of Hematology 116 (6), 988-992, 2010 | 402 | 2010 |
Pediatric high-grade glioma: biologically and clinically in need of new thinking C Jones, MA Karajannis, DTW Jones, MW Kieran, M Monje, SJ Baker, ... Neuro-oncology 19 (2), 153-161, 2017 | 381 | 2017 |
Drugging MYCN through an allosteric transition in Aurora kinase A WC Gustafson, JG Meyerowitz, EA Nekritz, J Chen, C Benes, E Charron, ... Cancer cell 26 (3), 414-427, 2014 | 290 | 2014 |
Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates N Kotecha, NJ Flores, JM Irish, EF Simonds, DS Sakai, S Archambeault, ... Cancer cell 14 (4), 335-343, 2008 | 283 | 2008 |
A platinum‐based covalent viability reagent for single‐cell mass cytometry HG Fienberg, EF Simonds, WJ Fantl, GP Nolan, B Bodenmiller Cytometry Part A 81 (6), 467-475, 2012 | 221 | 2012 |
The initial phase of an immune response functions to activate regulatory T cells WE O'Gorman, H Dooms, SH Thorne, WF Kuswanto, EF Simonds, ... The Journal of Immunology 183 (1), 332-339, 2009 | 188 | 2009 |
A kinase inhibitor targeted to mTORC1 drives regression in glioblastoma QW Fan, O Aksoy, RA Wong, S Ilkhanizadeh, CJ Novotny, WC Gustafson, ... Cancer cell 31 (3), 424-435, 2017 | 187 | 2017 |
Single-cell developmental classification of B cell precursor acute lymphoblastic leukemia at diagnosis reveals predictors of relapse Z Good, J Sarno, A Jager, N Samusik, N Aghaeepour, EF Simonds, ... Nature medicine 24 (4), 474-483, 2018 | 120 | 2018 |
Single-cell RNA-Seq of follicular lymphoma reveals malignant B-cell types and coexpression of T-cell immune checkpoints N Andor, EF Simonds, DK Czerwinski, J Chen, SM Grimes, ... Blood, The Journal of the American Society of Hematology 133 (10), 1119-1129, 2019 | 114 | 2019 |
Amir el JH Levine, EF Simonds, SC Bendall, KL Davis AD, Tadmor, MD, Litvin, O., Fienberg, HG, Jager, A., Zunder, ER, et al, 184-197, 2015 | 100 | 2015 |
AD Amir el, PO Krutzik, R SC Bendall, EF Simonds, P Qiu Finck, RV Bruggner, R. Melamed, A. Trejo, OI Ornatsky, RS Balderas, SK …, 2011 | 100 | 2011 |
A universal live cell barcoding-platform for multiplexed human single cell analysis FJ Hartmann, EF Simonds, SC Bendall Scientific reports 8 (1), 10770, 2018 | 93 | 2018 |
Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma EF Simonds, ED Lu, O Badillo, S Karimi, EV Liu, W Tamaki, C Rancan, ... Journal for immunotherapy of cancer 9 (6), 2021 | 56 | 2021 |