| Agonist-mediated activation of STING induces apoptosis in malignant B cells CHA Tang, JA Zundell, S Ranatunga, C Lin, Y Nefedova, JR Del Valle, ... Cancer research 76 (8), 2137-2152, 2016 | 279 | 2016 |
| Chemistry and biology of the aeruginosin family of serine protease inhibitors K Ersmark, JR Del Valle, S Hanessian Angewandte Chemie International Edition 47 (7), 1202-1223, 2008 | 210 | 2008 |
| Inhibition of ER stress–associated IRE-1/XBP-1 pathway reduces leukemic cell survival CHA Tang, S Ranatunga, CL Kriss, CL Cubitt, J Tao, JA Pinilla-Ibarz, ... The Journal of clinical investigation 124 (6), 2585-2598, 2014 | 187 | 2014 |
| Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival SJ Tavernier, F Osorio, L Vandersarren, J Vetters, N Vanlangenakker, ... Nature cell biology 19 (6), 698-710, 2017 | 115 | 2017 |
| Total synthesis of pactamycin BDS Prof. Dr. Stephen Hanessian, Dr. Ramkrishna Reddy Vakiti, Stéphane ... Angewandte Chemie International Edition 50 (15), 3497-3500, 2011 | 112* | 2011 |
| IRE1α RNase–dependent lipid homeostasis promotes survival in Myc-transformed cancers H Xie, CHA Tang, JH Song, A Mancuso, JR Del Valle, J Cao, Y Xiang, ... The Journal of clinical investigation 128 (4), 1300-1316, 2018 | 110 | 2018 |
| Stereoselective Synthesis of Boc‐Protected cis and trans‐4‐Trifluoromethylprolines by Asymmetric Hydrogenation Reactions JR Del Valle, M Goodman Angewandte Chemie 114 (9), 1670-1672, 2002 | 89 | 2002 |
| Total synthesis and structural confirmation of chlorodysinosin A S Hanessian, JR Del Valle, Y Xue, N Blomberg Journal of the American Chemical Society 128 (32), 10491-10495, 2006 | 86 | 2006 |
| Asymmetric hydrogenations for the synthesis of Boc-protected 4-alkylprolinols and prolines JR Del Valle, M Goodman The Journal of Organic Chemistry 68 (10), 3923-3931, 2003 | 83 | 2003 |
| Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice CL Kriss, JA Pinilla-Ibarz, AW Mailloux, JJ Powers, CHA Tang, CW Kang, ... Blood, The Journal of the American Society of Hematology 120 (5), 1027-1038, 2012 | 80 | 2012 |
| Adaptive endoplasmic reticulum stress signalling via IRE1α–XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells L Liu, M Zhao, X Jin, G Ney, KB Yang, F Peng, J Cao, T Iwawaki, ... Nature cell biology 21 (3), 328-337, 2019 | 72 | 2019 |
| Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization CHA Tang, S Chang, AW Paton, JC Paton, DI Gabrilovich, HL Ploegh, ... Journal of Cell Biology 217 (5), 1739-1755, 2018 | 65 | 2018 |
| Synthetic Studies in the Intramolecular Carbocyclization of N-Acyloxyiminium Ions. Stereoelectronic and Steric Implications of Nucleophilic Alkene, Alkyne, and … S Hanessian, M Tremblay, M Marzi, JR Del Valle The Journal of organic chemistry 70 (13), 5070-5085, 2005 | 53 | 2005 |
| Peptide N‐Amination Supports β‐Sheet Conformations MP Sarnowski, CW Kang, YM Elbatrawi, L Wojtas, JR Del Valle Angewandte Chemie International Edition 56 (8), 2083-2086, 2017 | 49 | 2017 |
| Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity S Ranatunga, CHA Tang, CW Kang, CL Kriss, BJ Kloppenburg, CCA Hu, ... Journal of medicinal chemistry 57 (10), 4289-4301, 2014 | 42 | 2014 |
| Structure-based organic synthesis of unnatural aeruginosin hybrids as potent inhibitors of thrombin S Hanessian, K Ersmark, X Wang, JR Del Valle, N Blomberg, Y Xue, ... Bioorganic & medicinal chemistry letters 17 (12), 3480-3485, 2007 | 40 | 2007 |
| Access to Enantiopure α-Hydrazino Acids for N-Amino Peptide Synthesis CW Kang, MP Sarnowski, YM Elbatrawi, JR Del Valle The Journal of Organic Chemistry 82 (3), 1833-1841, 2017 | 32 | 2017 |
| Total synthesis and structural revision of the presumed aeruginosins 205A and B S Hanessian, X Wang, K Ersmark, JR Del Valle, E Klegraf Organic Letters 11 (18), 4232-4235, 2009 | 32 | 2009 |
| Alkynyl Prins and Alkynyl Aza-Prins Annulations: Scope and Synthetic Applications S Abdul-Rashed, C Holt, AJ Frontier Synthesis 52 (14), 1991-2007, 2020 | 26 | 2020 |
| STING regulates BCR signaling in normal and malignant B cells CHA Tang, AC Lee, S Chang, Q Xu, A Shao, Y Lo, WT Spalek, ... Cellular & Molecular Immunology 18 (4), 1016-1031, 2021 | 25 | 2021 |
