The ERBB network: at last, cancer therapy meets systems biology Y Yarden, G Pines Nature Reviews Cancer 12 (8), 553-563, 2012 | 1045 | 2012 |
Genome-wide mapping of mutations at single-nucleotide resolution for protein, metabolic and genome engineering AD Garst, MC Bassalo, G Pines, SA Lynch, AL Halweg-Edwards, R Liu, ... Nature biotechnology 35 (1), 48-55, 2017 | 387 | 2017 |
Oncogenic mutant forms of EGFR: lessons in signal transduction and targets for cancer therapy G Pines, WJ Köstler, Y Yarden FEBS letters 584 (12), 2699-2706, 2010 | 249 | 2010 |
Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling K Shtiegman, BS Kochupurakkal, Y Zwang, G Pines, A Starr, A Vexler, ... Oncogene 26 (49), 6968-6978, 2007 | 173 | 2007 |
EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF G Tarcic, R Avraham, G Pines, I Amit, T Shay, Y Lu, Y Zwang, M Katz, ... The FASEB Journal 26 (4), 1582, 2012 | 109 | 2012 |
Bacterial recombineering: genome engineering via phage-based homologous recombination G Pines, EF Freed, JD Winkler, RT Gill ACS synthetic biology 4 (11), 1176-1185, 2015 | 100 | 2015 |
Deubiquitination of EGFR by Cezanne-1 contributes to cancer progression F Pareja, DA Ferraro, C Rubin, H Cohen-Dvashi, F Zhang, S Aulmann, ... Oncogene 31 (43), 4599-4608, 2012 | 100 | 2012 |
EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism G Pines, PH Huang, Y Zwang, FM White, Y Yarden Oncogene 29 (43), 5850-5860, 2010 | 80 | 2010 |
Kinase-mediated quasi-dimers of EGFR EM Bublil, G Pines, G Patel, G Fruhwirth, T Ng, Y Yarden The FASEB Journal 24 (12), 4744, 2010 | 70 | 2010 |
Multiplexed tracking of combinatorial genomic mutations in engineered cell populations RI Zeitoun, AD Garst, GD Degen, G Pines, TJ Mansell, TY Glebes, ... Nature biotechnology 33 (6), 631-637, 2015 | 61 | 2015 |
Codon compression algorithms for saturation mutagenesis G Pines, A Pines, AD Garst, RI Zeitoun, SA Lynch, RT Gill ACS synthetic biology 4 (5), 604-614, 2015 | 57 | 2015 |
SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors L Roth, S Srivastava, M Lindzen, A Sas-Chen, M Sheffer, M Lauriola, ... Science signaling 11 (515), eaan0949, 2018 | 53 | 2018 |
Differential detection of the tobamoviruses tomato mosaic virus (ToMV) and tomato brown rugose fruit virus (ToBRFV) using CRISPR-Cas12a DM Alon, H Hak, M Bornstein, G Pines, Z Spiegelman Plants 10 (6), 1256, 2021 | 46 | 2021 |
Refactoring the Genetic Code for Increased Evolvability G Pines, JD Winkler, A Pines, RT Gill mBio 8 (6), 2017 | 22 | 2017 |
The Resistome: A Comprehensive Database of Escherichia coli Resistance Phenotypes JD Winkler, AL Halweg-Edwards, KE Erickson, A Choudhury, G Pines, ... ACS Synthetic Biology 5 (12), 1566-1577, 2016 | 17 | 2016 |
Interfering with the Dimerization of the ErbB Receptors by Transmembrane Domain-Derived Peptides Inhibits Tumorigenic Growth in Vitro and in Vivo EM Bublil, T Cohen, CJ Arnusch, A Peleg, G Pines, S Lavi, Y Yarden, ... Biochemistry 55 (39), 5520-5530, 2016 | 13 | 2016 |
Genomic Deoxyxylulose Phosphate Reductoisomerase (DXR) Mutations Conferring Resistance to the Antimalarial Drug Fosmidomycin in E. coli G Pines, EJ Oh, MC Bassalo, A Choudhury, AD Garst, RG Fankhauser, ... ACS synthetic biology 7 (12), 2824-2832, 2018 | 12 | 2018 |
A web interface for codon compression AL Halweg-Edwards, G Pines, JD Winkler, A Pines, RT Gill ACS Synthetic Biology 5 (9), 1021-1023, 2016 | 11 | 2016 |
Rapid and sensitive on‐site genetic diagnostics of pest fruit flies using CRISPR‐Cas12a DM Alon, T Partosh, D Burstein, G Pines Pest Management Science 79 (1), 68-75, 2023 | 10 | 2023 |
Predicting drug resistance using deep mutational scanning G Pines, RG Fankhauser, CA Eckert Molecules 25 (9), 2265, 2020 | 9 | 2020 |