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Kevin P Bateman
Kevin P Bateman
在 merck.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Nanomole-scale high-throughput chemistry for the synthesis of complex molecules
A Buitrago Santanilla, EL Regalado, T Pereira, M Shevlin, K Bateman, ...
Science 347 (6217), 49-53, 2015
5612015
Carrageenan-induced paw edema in rat elicits a predominant prostaglandin E2 (PGE2) response in the central nervous system associated with the induction of microsomal PGE2 …
J Guay, K Bateman, R Gordon, J Mancini, D Riendeau
Journal of Biological Chemistry 279 (23), 24866-24872, 2004
3162004
MSE with mass defect filtering for in vitro and in vivo metabolite identification
KP Bateman, J Castro‐Perez, M Wrona, JP Shockcor, K Yu, R Oballa, ...
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2007
3122007
‘All‐in‐one’analysis for metabolite identification using liquid chromatography/hybrid quadrupole time‐of‐flight mass spectrometry with collision energy switching
M Wrona, T Mauriala, KP Bateman, RJ Mortishire‐Smith, D O'Connor
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2005
2092005
Discovery of a potent and selective prostaglandin D2 receptor antagonist,[(3 R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1, 2, 3, 4-tetrahydrocyclopenta [b] indol-3-yl …
CF Sturino, G O'Neill, N Lachance, M Boyd, C Berthelette, M Labelle, L Li, ...
Journal of medicinal chemistry 50 (4), 794-806, 2007
2082007
Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer
KP Bateman, M Kellmann, H Muenster, R Papp, L Taylor
Journal of the American Society for Mass Spectrometry 20, 1441-1450, 2009
2002009
γ-Aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action
GYK Ng, S Bertrand, R Sullivan, N Ethier, J Wang, J Yergey, M Belley, ...
Molecular Pharmacology 59 (1), 144-152, 2001
1882001
Mass spectral analyses of microcystins from toxic cyanobacteria using on-line chromatographic and electrophoretic separations
KP Bateman, P Thibault, DJ Douglas, RL White
Journal of Chromatography A 712 (1), 253-268, 1995
1781995
Discovery stage pharmacokinetics using dried blood spots
P Beaudette, KP Bateman
Journal of Chromatography B 809 (1), 153-158, 2004
1582004
Deletion of microsomal prostaglandin E2 (PGE2) synthase-1 reduces inducible and basal PGE2 production and alters the gastric prostanoid profile
L Boulet, M Ouellet, KP Bateman, D Ethier, MD Percival, D Riendeau, ...
Journal of Biological Chemistry 279 (22), 23229-23237, 2004
1472004
Disposable emitters for on‐line capillary zone electrophoresis/nanoelectrospray mass spectrometry
KP Bateman, RL White, P Thibault
Rapid communications in mass spectrometry 11 (3), 307-315, 1997
1351997
Validation of a microdose probe drug cocktail for clinical drug interaction assessments for drug transporters and CYP3A
T Prueksaritanont, DA Tatosian, X Chu, R Railkar, R Evers, ...
Clinical Pharmacology & Therapeutics 101 (4), 519-530, 2017
1332017
High-throughput cytochrome P450 inhibition assays using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry
J Wu, CS Hughes, P Picard, S Letarte, M Gaudreault, JF Lévesque, ...
Analytical Chemistry 79 (12), 4657-4665, 2007
1312007
2012 White Paper on recent issues in bioanalysis and alignment of multiple guidelines
B DeSilva, F Garofolo, M Rocci, S Martinez, I Dumont, F Landry, C Dicaire, ...
Bioanalysis 4 (18), 2213-2226, 2012
932012
The YRD motif is a major determinant of substrate and inhibitor specificity in T-cell protein-tyrosine phosphatase
E Asante-Appiah, K Ball, K Bateman, K Skorey, R Friesen, C Desponts, ...
Journal of Biological Chemistry 276 (28), 26036-26043, 2001
772001
Extractability-mediated stability bias and hematocrit impact: high extraction recovery is critical to feasibility of volumetric adsorptive microsampling (VAMS) in regulated …
I Xie, Y Xu, M Anderson, M Wang, L Xue, S Breidinger, D Goykhman, ...
Journal of pharmaceutical and biomedical analysis 156, 58-66, 2018
722018
Catalytic inactivation of protein tyrosine phosphatase CD45 and protein tyrosine phosphatase 1B by polyaromatic quinones
Q Wang, D Dubé, RW Friesen, TG LeRiche, KP Bateman, L Trimble, ...
Biochemistry 43 (14), 4294-4303, 2004
682004
Merck’s perspective on the implementation of dried blood spot technology in clinical drug development–why, when and how
Y Xu, EJ Woolf, NGB Agrawal, P Kothare, V Pucci, KP Bateman
Bioanalysis 5 (3), 341-350, 2013
672013
High-sensitivity nanolc− ms/ms analysis of urinary desmosine and isodesmosine
M Boutin, C Berthelette, FG Gervais, MB Scholand, J Hoidal, MF Leppert, ...
Analytical chemistry 81 (5), 1881-1887, 2009
652009
The use of 3-[2-(N, N-diethyl-N-methylammonium) ethyl]-7-methoxy-4-methylcoumarin (AMMC) as a specific CYP2D6 probe in human liver microsomes
N Chauret, B Dobbs, RL Lackman, K Bateman, DA Nicoll-Griffith, ...
Drug metabolism and disposition 29 (9), 1196-1200, 2001
652001
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