Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution N Maherali, R Sridharan, W Xie, J Utikal, S Eminli, K Arnold, M Stadtfeld, ... Cell stem cell 1 (1), 55-70, 2007 | 2263 | 2007 |
Generation of human induced pluripotent stem cells from dermal fibroblasts WE Lowry, L Richter, R Yachechko, AD Pyle, J Tchieu, R Sridharan, ... Proceedings of the National Academy of Sciences 105 (8), 2883-2888, 2008 | 1405 | 2008 |
Role of the murine reprogramming factors in the induction of pluripotency R Sridharan, J Tchieu, MJ Mason, R Yachechko, E Kuoy, S Horvath, ... Cell 136 (2), 364-377, 2009 | 771 | 2009 |
Chd1 regulates open chromatin and pluripotency of embryonic stem cells A Gaspar-Maia, A Alajem, F Polesso, R Sridharan, MJ Mason, ... nature 460 (7257), 863-868, 2009 | 605 | 2009 |
Selective and antagonistic functions of SWI/SNF and Mi-2β nucleosome remodeling complexes during an inflammatory response VR Ramirez-Carrozzi, AA Nazarian, CC Li, SL Gore, R Sridharan, ... Genes & development 20 (3), 282-296, 2006 | 493 | 2006 |
Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency R Sridharan, M Gonzales-Cope, C Chronis, G Bonora, R McKee, ... Nature cell biology 15 (7), 872-882, 2013 | 258 | 2013 |
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells W Xie, C Song, NL Young, AS Sperling, F Xu, R Sridharan, AE Conway, ... Molecular cell 33 (4), 417-427, 2009 | 223 | 2009 |
Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor P Papathanasiou, AC Perkins, BS Cobb, R Ferrini, R Sridharan, ... Immunity 19 (1), 131-144, 2003 | 170 | 2003 |
Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes R Sridharan, ST Smale Journal of Biological Chemistry 282 (41), 30227-30238, 2007 | 153 | 2007 |
Primary cilium-mediated retinal pigment epithelium maturation is disrupted in ciliopathy patient cells HL May-Simera, Q Wan, BS Jha, J Hartford, V Khristov, R Dejene, ... Cell reports 22 (1), 189-205, 2018 | 139 | 2018 |
A predictive modeling approach for cell line-specific long-range regulatory interactions S Roy, AF Siahpirani, D Chasman, S Knaack, F Ay, R Stewart, M Wilson, ... Nucleic acids research 43 (18), 8694-8712, 2015 | 137 | 2015 |
Beta cell dedifferentiation induced by IRE1α deletion prevents type 1 diabetes H Lee, YS Lee, Q Harenda, S Pietrzak, HZ Oktay, S Schreiber, Y Liao, ... Cell metabolism 31 (4), 822-836. e5, 2020 | 115 | 2020 |
Mediator coordinates PIC assembly with recruitment of CHD1 JJ Lin, LW Lehmann, G Bonora, R Sridharan, AA Vashisht, N Tran, ... Genes & development 25 (20), 2198-2209, 2011 | 107 | 2011 |
Methyl-metabolite depletion elicits adaptive responses to support heterochromatin stability and epigenetic persistence SA Haws, D Yu, C Ye, CK Wille, LC Nguyen, KA Krautkramer, ... Molecular cell 78 (2), 210-223. e8, 2020 | 62 | 2020 |
The role of α-ketoglutarate–dependent proteins in pluripotency acquisition and maintenance KA Tran, CM Dillingham, R Sridharan Journal of Biological Chemistry 294 (14), 5408-5419, 2019 | 59 | 2019 |
Defining reprogramming checkpoints from single-cell analyses of induced pluripotency KA Tran, SJ Pietrzak, NZ Zaidan, AF Siahpirani, SG McCalla, AS Zhou, ... Cell reports 27 (6), 1726-1741. e5, 2019 | 53 | 2019 |
Collaborative rewiring of the pluripotency network by chromatin and signalling modulating pathways KA Tran, SA Jackson, ZPG Olufs, NZ Zaidan, N Leng, C Kendziorski, ... Nature communications 6 (1), 6188, 2015 | 44 | 2015 |
Illuminating the black box of reprogramming R Sridharan, K Plath Cell stem cell 2 (4), 295-297, 2008 | 44 | 2008 |
Inference of cell type-specific gene regulatory networks on cell lineages from single cell omic datasets S Zhang, S Pyne, S Pietrzak, S Halberg, SG McCalla, AF Siahpirani, ... Nature Communications 14 (1), 3064, 2023 | 34 | 2023 |
Initial characterization of histone H3 serine 10 O-acetylation LMP Britton, A Newhart, NV Bhanu, R Sridharan, M Gonzales-Cope, ... Epigenetics 8 (10), 1101-1113, 2013 | 33 | 2013 |