A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function S Feske, Y Gwack, M Prakriya, S Srikanth, SH Puppel, B Tanasa, ... Nature 441 (7090), 179-185, 2006 | 2681 | 2006 |
Orai1 is an essential pore subunit of the CRAC channel M Prakriya, S Feske, Y Gwack, S Srikanth, A Rao, PG Hogan Nature 443 (7108), 230-233, 2006 | 1653 | 2006 |
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT Y Gwack, S Sharma, J Nardone, B Tanasa, A Iuga, S Srikanth, H Okamura, ... Nature 441 (7093), 646-650, 2006 | 490 | 2006 |
Biochemical and functional characterization of Orai proteins Y Gwack, S Srikanth, S Feske, F Cruz-Guilloty, M Oh-hora, DS Neems, ... Journal of Biological Chemistry 282 (22), 16232-16243, 2007 | 489 | 2007 |
Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx: evidence for similarities in store-operated and calcium release-activated … HL Ong, KT Cheng, X Liu, BC Bandyopadhyay, BC Paria, J Soboloff, ... Journal of Biological Chemistry 282 (12), 9105-9116, 2007 | 451 | 2007 |
C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity DW Kim, Y Gwack, JH Han, J Choe Biochemical and biophysical research communications 215 (1), 160-166, 1995 | 436 | 1995 |
Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes Y Gwack, S Feske, S Srikanth, PG Hogan, A Rao Cell calcium 42 (2), 145-156, 2007 | 401 | 2007 |
Hair loss and defective T-and B-cell function in mice lacking ORAI1 Y Gwack, S Srikanth, M Oh-Hora, PG Hogan, ED Lamperti, M Yamashita, ... Molecular and cellular biology, 2008 | 350 | 2008 |
Global changes in Kaposi's sarcoma-associated virus gene expression patterns following expression of a tetracycline-inducible Rta transactivator H Nakamura, M Lu, Y Gwack, J Souvlis, SL Zeichner, JU Jung Journal of virology 77 (7), 4205-4220, 2003 | 328 | 2003 |
The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum S Srikanth, JS Woo, B Wu, YM El-Sherbiny, J Leung, K Chupradit, L Rice, ... Nature immunology 20 (2), 152-162, 2019 | 277 | 2019 |
A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells S Srikanth, HJ Jung, KD Kim, P Souda, J Whitelegge, Y Gwack Nature cell biology 12 (5), 436-446, 2010 | 276 | 2010 |
The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells S Bertin, Y Aoki-Nonaka, PR De Jong, LL Nohara, H Xu, SR Stanwood, ... Nature immunology 15 (11), 1055-1063, 2014 | 252 | 2014 |
Characterization of RNA binding activity and RNA helicase activity of the hepatitis C virus NS3 protein Y Gwack, DW Kim, JH Han, J Choe Biochemical and biophysical research communications 225 (2), 654-659, 1996 | 205 | 1996 |
CREB-binding protein and histone deacetylase regulate the transcriptional activity of Kaposi's sarcoma-associated herpesvirus open reading frame 50 Y Gwack, H Byun, S Hwang, C Lim, J Choe Journal of virology 75 (4), 1909-1917, 2001 | 184 | 2001 |
Mutational analysis of the hepatitis C virus RNA helicase DW Kim, J Kim, Y Gwack, JH Han, J Choe Journal of Virology 71 (12), 9400-9409, 1997 | 170 | 1997 |
Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps VA Barr, KM Bernot, S Srikanth, Y Gwack, L Balagopalan, CK Regan, ... Molecular biology of the cell 19 (7), 2802-2817, 2008 | 169 | 2008 |
Latency-associated nuclear antigen of Kaposi’s sarcoma-associated herpesvirus (human herpesvirus-8) binds ATF4/CREB2 and inhibits its transcriptional activation activity C Lim, H Sohn, Y Gwack, J Choe Journal of General Virology 81 (11), 2645-2652, 2000 | 150 | 2000 |
Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1) S Srikanth, M Jew, KD Kim, MK Yee, J Abramson, Y Gwack Proceedings of the National Academy of Sciences 109 (22), 8682-8687, 2012 | 137 | 2012 |
The transcriptional activity of cAMP response element-binding protein-binding protein is modulated by the latency associated nuclear antigen of Kaposi's sarcoma-associated … C Lim, Y Gwack, S Hwang, S Kim, J Choe Journal of Biological Chemistry 276 (33), 31016-31022, 2001 | 131 | 2001 |
Principal role of TRAP/mediator and SWI/SNF complexes in Kaposi's sarcoma-associated herpesvirus RTA-mediated lytic reactivation Y Gwack, HJ Baek, H Nakamura, SH Lee, M Meisterernst, RG Roeder, ... Molecular and Cellular Biology 23 (6), 2055-2067, 2003 | 130 | 2003 |