Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin AM Intlekofer, N Takemoto, EJ Wherry, SA Longworth, JT Northrup, ... Nature Immunology 6 (12), 1236-1244, 2005 | 1485 | 2005 |
Asymmetric T lymphocyte division in the initiation of adaptive immune responses JT Chang, VR Palanivel, I Kinjyo, F Schambach, AM Intlekofer, ... Science 315 (5819), 1687, 2007 | 1078 | 2007 |
A Role for the Transcriptional Repressor Blimp-1 in CD8+ T Cell Exhaustion during Chronic Viral Infection H Shin, SD Blackburn, AM Intlekofer, C Kao, JM Angelosanto, SL Reiner, ... Immunity 31 (2), 309-320, 2009 | 574 | 2009 |
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection C Kao, KJ Oestreich, MA Paley, A Crawford, JM Angelosanto, MAA Ali, ... Nature Immunology 12 (7), 663-671, 2011 | 550 | 2011 |
Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche A Banerjee, SM Gordon, AM Intlekofer, MA Paley, EC Mooney, T Lindsten, ... The Journal of Immunology 185 (9), 4988-4992, 2010 | 546 | 2010 |
Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin AM Intlekofer, A Banerjee, N Takemoto, SM Gordon, CS DeJong, H Shin, ... Science 321 (5887), 408, 2008 | 499 | 2008 |
Hypoxia induces production of L-2-hydroxyglutarate AM Intlekofer, RG Dematteo, S Venneti, LWS Finley, C Lu, AR Judkins, ... Cell metabolism 22 (2), 304-311, 2015 | 480 | 2015 |
Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation N Takemoto, AM Intlekofer, JT Northrup, EJ Wherry, SL Reiner The Journal of Immunology 177 (11), 7515-7519, 2006 | 469 | 2006 |
At the bench: Preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy AM Intlekofer, CB Thompson Journal of Leukocyte Biology, 2013 | 446 | 2013 |
Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells AM Intlekofer, N Takemoto, C Kao, A Banerjee, F Schambach, ... The Journal of Experimental Medicine 204 (9), 2015-2021, 2007 | 369 | 2007 |
The public repository of xenografts enables discovery and randomized phase II-like trials in mice EC Townsend, MA Murakami, A Christodoulou, AL Christie, J Köster, ... Cancer cell 29 (4), 574-586, 2016 | 339 | 2016 |
Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms R Rampal, J Ahn, O Abdel-Wahab, M Nahas, K Wang, D Lipson, GA Otto, ... Proceedings of the National Academy of Sciences 111 (50), E5401-E5410, 2014 | 315 | 2014 |
As extracellular glutamine levels decline, asparagine becomes an essential amino acid NN Pavlova, S Hui, JM Ghergurovich, J Fan, AM Intlekofer, RM White, ... Cell metabolism 27 (2), 428-438. e5, 2018 | 301 | 2018 |
Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting J He, O Abdel-Wahab, MK Nahas, K Wang, RK Rampal, AM Intlekofer, ... Blood, The Journal of the American Society of Hematology 127 (24), 3004-3014, 2016 | 290 | 2016 |
Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations AM Intlekofer, AH Shih, B Wang, A Nazir, AS Rustenburg, SK Albanese, ... Nature 559 (7712), 125-129, 2018 | 273 | 2018 |
Metabolic signatures of cancer cells and stem cells AM Intlekofer, LWS Finley Nature metabolism 1 (2), 177-188, 2019 | 269 | 2019 |
L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH AM Intlekofer, B Wang, H Liu, H Shah, C Carmona-Fontaine, ... Nature chemical biology 13 (5), 494-500, 2017 | 251 | 2017 |
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A Y Yashiro-Ohtani, Y He, T Ohtani, ME Jones, O Shestova, L Xu, TC Fang, ... Genes & Development 23 (14), 1665-1676, 2009 | 216 | 2009 |
Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, ... Nature 574 (7777), 273-277, 2019 | 192 | 2019 |
Induction of sarcomas by mutant IDH2 C Lu, S Venneti, A Akalin, F Fang, PS Ward, RG DeMatteo, AM Intlekofer, ... Genes & development 27 (18), 1986-1998, 2013 | 184 | 2013 |