One‐step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment LM Grav, JS Lee, S Gerling, TB Kallehauge, AH Hansen, S Kol, GM Lee, ... Biotechnology journal 10 (9), 1446-1456, 2015 | 153 | 2015 |
A Markov chain model for N-linked protein glycosylation–towards a low-parameter tool for model-driven glycoengineering PN Spahn, AH Hansen, HG Hansen, J Arnsdorf, HF Kildegaard, NE Lewis Metabolic engineering 33, 52-66, 2016 | 105 | 2016 |
Multiplex secretome engineering enhances recombinant protein production and purity S Kol, D Ley, T Wulff, M Decker, J Arnsdorf, S Schoffelen, AH Hansen, ... Nature communications 11 (1), 1908, 2020 | 91 | 2020 |
Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles T Amann, AH Hansen, S Kol, HG Hansen, J Arnsdorf, S Nallapareddy, ... Metabolic Engineering 52, 143-152, 2019 | 59 | 2019 |
Predictive glycoengineering of biosimilars using a Markov chain glycosylation model PN Spahn, AH Hansen, S Kol, BG Voldborg, NE Lewis Biotechnology journal 12 (2), 1600489, 2017 | 43 | 2017 |
LC-MS analysis reveals the presence of graminan-and neo-type fructans in wheat grains J Verspreet, AH Hansen, E Dornez, JA Delcour, W Van den Ende, ... Journal of Cereal Science 61, 133-138, 2015 | 43 | 2015 |
Awakening dormant glycosyltransferases in CHO cells with CRISPRa KJC Karottki, H Hefzi, K Xiong, I Shamie, AH Hansen, S Li, LE Pedersen, ... Biotechnology and bioengineering 117 (2), 593-598, 2020 | 36 | 2020 |
Baicalein reduces oxidative stress in CHO cell cultures and improves recombinant antibody productivity TK Ha, AH Hansen, S Kol, HF Kildegaard, GM Lee Biotechnology Journal 13 (3), 1700425, 2018 | 35 | 2018 |
CRISPR/Cas9‐Multiplexed Editing of Chinese Hamster Ovary B4Gal‐T1, 2, 3, and 4 Tailors N‐Glycan Profiles of Therapeutics and Secreted Host Cell Proteins T Amann, AH Hansen, S Kol, GM Lee, MR Andersen, HF Kildegaard Biotechnology journal 13 (10), 1800111, 2018 | 33 | 2018 |
Building a fructan LC–MS2 library and its application to reveal the fine structure of cereal grain fructans J Verspreet, AH Hansen, SJ Harrison, R Vergauwen, W Van den Ende, ... Carbohydrate Polymers 174, 343-351, 2017 | 23 | 2017 |
A Markov model of glycosylation elucidates isozyme specificity and glycosyltransferase interactions for glycoengineering C Liang, AWT Chiang, AH Hansen, J Arnsdorf, S Schoffelen, ... Current research in biotechnology 2, 22-36, 2020 | 22 | 2020 |
Knockout of sialidase and pro-apoptotic genes in Chinese hamster ovary cells enables the production of recombinant human erythropoietin in fed-batch cultures TK Ha, AH Hansen, HF Kildegaard, GM Lee Metabolic engineering 57, 182-192, 2020 | 22 | 2020 |
De-bugging and maximizing plant cytochrome P450 production in Escherichia coli with C-terminal GFP fusions U Christensen, D Vazquez-Albacete, KM Søgaard, T Hobel, MT Nielsen, ... Applied microbiology and biotechnology 101, 4103-4113, 2017 | 21 | 2017 |
BiP inducer X: an ER stress inhibitor for enhancing recombinant antibody production in CHO cell culture TK Ha, AH Hansen, HF Kildegaard, GM Lee Biotechnology Journal 14 (10), 1900130, 2019 | 19 | 2019 |
A new high-throughput LC-MS method for the analysis of complex fructan mixtures J Verspreet, A Holmgaard Hansen, E Dornez, CM Courtin, SJ Harrison Analytical and bioanalytical chemistry 406, 4785-4788, 2014 | 16 | 2014 |
Glycoengineering of Aspergillus nidulans to produce precursors for humanized N-glycan structures DC Anyaogu, AH Hansen, JB Hoof, NI Majewska, FJ Contesini, JT Paul, ... Metabolic engineering 67, 153-163, 2021 | 11 | 2021 |
A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells I Shamie, SH Duttke, KJC Karottki, CZ Han, AH Hansen, H Hefzi, K Xiong, ... NAR genomics and bioinformatics 3 (3), lqab061, 2021 | 11 | 2021 |
Liquid chromatography/mass spectrometry analysis of branched fructans produced in vitro with 13C‐labeled substrates J Verspreet, A Holmgaard Hansen, E Dornez, JA Delcour, SJ Harrison, ... Rapid Communications in Mass Spectrometry 28 (20), 2191-2200, 2014 | 10 | 2014 |
CHOGlycoNET: Comprehensive glycosylation reaction network for CHO cells P Kotidis, R Donini, J Arnsdorf, AH Hansen, BGR Voldborg, AWT Chiang, ... Metabolic Engineering 76, 87-96, 2023 | 6 | 2023 |
Prevalence of joint hypermobility in patients with fibromyalgia JJ Lykkegaard, AH Hansen, B Danneskiold-Samsoe J. Muscu-loskel Pain. 3 (S1), 117, 1997 | 5 | 1997 |