Bayesian deconvolution of mass and ion mobility spectra: from binary interactions to polydisperse ensembles MT Marty, AJ Baldwin, EG Marklund, GKA Hochberg, JLP Benesch, ... Analytical chemistry 87 (8), 4370-4376, 2015 | 815 | 2015 |
The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity GKA Hochberg, H Ecroyd, C Liu, D Cox, D Cascio, MR Sawaya, ... Proceedings of the National Academy of Sciences 111 (16), E1562-E1570, 2014 | 221 | 2014 |
Reconstructing ancient proteins to understand the causes of structure and function GKA Hochberg, JW Thornton Annual review of biophysics 46 (1), 247-269, 2017 | 159 | 2017 |
An ultra-stable gold-coordinated protein cage displaying reversible assembly AD Malay, N Miyazaki, A Biela, S Chakraborti, K Majsterkiewicz, I Stupka, ... Nature 569 (7756), 438-442, 2019 | 154 | 2019 |
Origin of complexity in haemoglobin evolution AS Pillai, SA Chandler, Y Liu, AV Signore, CR Cortez-Romero, ... Nature 581 (7809), 480-485, 2020 | 119 | 2020 |
Evolution of protein specificity: insights from ancestral protein reconstruction MA Siddiq, GKA Hochberg, JW Thornton Current opinion in structural biology 47, 113-122, 2017 | 106 | 2017 |
A hydrophobic ratchet entrenches molecular complexes GKA Hochberg, Y Liu, EG Marklund, BPH Metzger, A Laganowsky, ... Nature 588 (7838), 503-508, 2020 | 98 | 2020 |
Dynamical structure of αB-crystallin GKA Hochberg, JLP Benesch Progress in biophysics and molecular biology 115 (1), 11-20, 2014 | 96 | 2014 |
C-terminal interactions mediate the quaternary dynamics of αB-crystallin GR Hilton, GKA Hochberg, A Laganowsky, SI McGinnigle, AJ Baldwin, ... Philosophical Transactions of the Royal Society B: Biological Sciences 368 …, 2013 | 82 | 2013 |
Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions GKA Hochberg, DA Shepherd, EG Marklund, I Santhanagoplan, ... Science 359 (6378), 930-935, 2018 | 63 | 2018 |
It takes a dimer to tango: Oligomeric small heat shock proteins dissociate to capture substrate I Santhanagopalan, MT Degiacomi, DA Shepherd, GKA Hochberg, ... Journal of Biological Chemistry 293 (51), 19511-19521, 2018 | 50 | 2018 |
Evolution of increased complexity and specificity at the dawn of form I Rubiscos L Schulz, Z Guo, J Zarzycki, W Steinchen, JM Schuller, T Heimerl, S Prinz, ... Science 378 (6616), 155-160, 2022 | 47 | 2022 |
Non-adaptive complexity and biochemical function L Schulz, FL Sendker, GKA Hochberg Current Opinion in Structural Biology 73, 102339, 2022 | 21 | 2022 |
Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis PI Giammarinaro, MKM Young, W Steinchen, CN Mais, G Hochberg, ... Nature microbiology 7 (9), 1442-1452, 2022 | 18 | 2022 |
Structure and mechanistic features of the prokaryotic minimal RNase P R Feyh, NB Waeber, S Prinz, PI Giammarinaro, G Bange, G Hochberg, ... Elife 10, e70160, 2021 | 16 | 2021 |
Simple mechanisms for the evolution of protein complexity AS Pillai, GKA Hochberg, JW Thornton Protein science 31 (11), e4449, 2022 | 15 | 2022 |
Structural basis for lipid and copper regulation of the ABC transporter MsbA J Lyu, C Liu, T Zhang, S Schrecke, NP Elam, C Packianathan, ... Nature Communications 13 (1), 7291, 2022 | 12 | 2022 |
Comment on “Ancient origins of allosteric activation in a Ser-Thr kinase” Y Park, JEJ Patton, GKA Hochberg, JW Thornton Science 370 (6519), eabc8301, 2020 | 12 | 2020 |
Fortuitously compatible protein surfaces primed allosteric control in cyanobacterial photoprotection N Steube, M Moldenhauer, P Weiland, D Saman, A Kilb, ... Nature Ecology & Evolution 7 (5), 756-767, 2023 | 9 | 2023 |
GGDEF domain as spatial on-switch for a phosphodiesterase by interaction with landmark protein HubP T Rick, V Kreiling, A Höing, S Fiedler, T Glatter, W Steinchen, G Hochberg, ... npj Biofilms and Microbiomes 8 (1), 35, 2022 | 9 | 2022 |