Structural basis for the anticoagulant activity of the thrombin–thrombomodulin complex P Fuentes-Prior, Y Iwanaga, R Huber, R Pagila, G Rumennik, M Seto, ... Nature 404 (6777), 518-525, 2000 | 419 | 2000 |
Rubber elongation factor from Hevea brasiliensis: identification, characterization, and role in rubber biosynthesis. MS Dennis, DR Light Journal of Biological Chemistry 264 (31), 18608-18617, 1989 | 343 | 1989 |
Characteristics of the cofactor requirements for the superoxide-generating NADPH oxidase of human polymorphonuclear leukocytes DR Light, C Walsh, AM O'Callaghan, EJ Goetzl, AI Tauber Biochemistry 20 (6), 1468-1476, 1981 | 296 | 1981 |
Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity. A potential rapid mechanism for modulation of coagulation. CB Glaser, J Morser, JH Clarke, E Blasko, K McLean, I Kuhn, RJ Chang, ... The Journal of clinical investigation 90 (6), 2565-2573, 1992 | 292 | 1992 |
Production of 2-Keto-L-Gulonate, an Intermediate in L-Ascorbate Synthesis, by a Genetically Modified Erwinia herbicola S Anderson, CB Marks, R Lazarus, J Miller, K Stafford, J Seymour, D Light, ... Science 230 (4722), 144-149, 1985 | 273 | 1985 |
The human growth hormone receptor. Secretion from Escherichia coli and disulfide bonding pattern of the extracellular binding domain. G Fuh, MG Mulkerrin, S Bass, N McFarland, M Brochier, JH Bourell, ... Journal of Biological Chemistry 265 (6), 3111-3115, 1990 | 250 | 1990 |
Studies on the chirality of sulfoxidation catalyzed by bacterial flavoenzyme cyclohexanone monooxygenase and hog liver FAD-containing monooxygenase DR Light, DJ Waxman, C Walsh Biochemistry 21 (10), 2490-2498, 1982 | 199 | 1982 |
An inhibitor of activated thrombin-activatable fibrinolysis inhibitor potentiates tissue-type plasminogen activator-induced thrombolysis in a rabbit jugular vein thrombolysis model M Nagashima, M Werner, M Wang, L Zhao, DR Light, R Pagila, J Morser, ... Thrombosis research 98 (4), 333-342, 2000 | 191 | 2000 |
Fasudil, a Rho-kinase inhibitor, attenuates angiotensin II–induced abdominal aortic aneurysm in apolipoprotein E–deficient mice by inhibiting apoptosis and proteolysis YX Wang, B Martin-McNulty, V da Cunha, J Vincelette, X Lu, Q Feng, ... Circulation 111 (17), 2219-2226, 2005 | 163 | 2005 |
Preparation, Characterization, and the Crystal Structure of the Inhibitor ZK-807834 (CI-1031) Complexed with Factor Xa, M Adler, DD Davey, GB Phillips, SH Kim, J Jancarik, G Rumennik, ... Biochemistry 39 (41), 12534-12542, 2000 | 137 | 2000 |
Amino acid sequence of rubber elongation factor protein associated with rubber particles in Hevea latex MS Dennis, WJ Henzel, J Bell, W Kohr, DR Light Journal of Biological Chemistry 264 (31), 18618-18626, 1989 | 137 | 1989 |
Purification of a prenyltransferase that elongates cis-polyisoprene rubber from the latex of Hevea brasiliensis DR Light, MS Dennis Journal of Biological Chemistry 264 (31), 18589-18597, 1989 | 135 | 1989 |
Chiral sulfoxidations catalyzed by rat liver cytochromes P-450 DJ Waxman, DR Light, C Walsh Biochemistry 21 (10), 2499-2507, 1982 | 128 | 1982 |
Analytical and preparative high-performance liquid chromatography separation of flavin and flavin analog coenzymes DR Light, C Walsh, MA Marletta Analytical biochemistry 109 (1), 87-93, 1980 | 117 | 1980 |
Crystal Structures of Two Potent Nonamidine Inhibitors Bound to Factor Xa, M Adler, MJ Kochanny, B Ye, G Rumennik, DR Light, S Biancalana, ... Biochemistry 41 (52), 15514-15523, 2002 | 115 | 2002 |
Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture JA Xuan, D Schneider, P Toy, R Lin, A Newton, Y Zhu, S Finster, D Vogel, ... Cancer research 66 (7), 3611-3619, 2006 | 99 | 2006 |
In Vivo Biodistribution, PET Imaging, and Tumor Accumulation of 86Y-and 111In-Antimindin/RG-1, Engineered Antibody Fragments in LNCaP Tumor–Bearing Nude Mice DW Schneider, T Heitner, B Alicke, DR Light, K McLean, N Satozawa, ... Journal of Nuclear Medicine 50 (3), 435-443, 2009 | 97 | 2009 |
Modulation of glycosaminoglycan addition in naturally expressed and recombinant human thrombomodulin. JH Lin, K McLean, J Morser, TA Young, RM Wydro, WH Andrews, ... Journal of Biological Chemistry 269 (40), 25021-25030, 1994 | 97 | 1994 |
Inhibition of Rho-kinase by fasudil attenuated angiotensin II-induced cardiac hypertrophy in apolipoprotein E deficient mice YX Wang, V da Cunha, B Martin-McNulty, J Vincelette, W Li, DF Choy, ... European journal of pharmacology 512 (2-3), 215-222, 2005 | 92 | 2005 |
Steroid binding properties of beef adrenal cortical cytochrome P-450 which catalyzes the conversion of cholesterol into pregnenolone. NR Orme-Johnson, DR Light, RW White-Stevens, WH Orme-Johnson Journal of Biological Chemistry 254 (6), 2103-2111, 1979 | 91 | 1979 |