Clinical relevance of biomarkers of oxidative stress J Frijhoff, PG Winyard, N Zarkovic, SS Davies, R Stocker, D Cheng, ... Antioxidants & redox signaling 23 (14), 1144-1170, 2015 | 872 | 2015 |
Regulation of protein tyrosine phosphatases by reversible oxidation A Östman, J Frijhoff, Å Sandin, FD Böhmer The journal of biochemistry 150 (4), 345-356, 2011 | 336 | 2011 |
Cancer-associated fibroblasts expressing CXCL14 rely upon NOS1-derived nitric oxide signaling for their tumor-supporting properties M Augsten, E Sjöberg, O Frings, SU Vorrink, J Frijhoff, E Olsson, Å Borg, ... Cancer research 74 (11), 2999-3010, 2014 | 144 | 2014 |
12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases M Conrad, Å Sandin, H Förster, A Seiler, J Frijhoff, M Dagnell, ... Proceedings of the National Academy of Sciences 107 (36), 15774-15779, 2010 | 109 | 2010 |
Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling M Dagnell, J Frijhoff, I Pader, M Augsten, B Boivin, J Xu, PK Mandal, ... Proceedings of the National Academy of Sciences 110 (33), 13398-13403, 2013 | 106 | 2013 |
Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype X Shen, MA Burguillos, AM Osman, J Frijhoff, A Carrillo-Jimenez, ... Nature immunology 17 (11), 1282-1290, 2016 | 93 | 2016 |
Differential up-regulation of MAP kinase phosphatases MKP3/DUSP6 and DUSP5 by Ets2 and c-Jun converge in the control of the growth arrest versus proliferation response of MCF-7 … CE Nunes-Xavier, C Tarrega, R Cejudo-Marin, J Frijhoff, Å Sandin, ... Journal of Biological Chemistry 285 (34), 26417-26430, 2010 | 70 | 2010 |
Regulation of protein tyrosine phosphatase oxidation in cell adhesion and migration J Frijhoff, M Dagnell, R Godfrey, A Östman Antioxidants & redox signaling 20 (13), 1994-2010, 2014 | 66 | 2014 |
Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis J Hellfritsch, J Kirsch, M Schneider, T Fluege, M Wortmann, J Frijhoff, ... Antioxidants & redox signaling 22 (11), 938-950, 2015 | 55 | 2015 |
The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation J Frijhoff, M Dagnell, M Augsten, E Beltrami, M Giorgio, A Östman Free Radical Biology and Medicine 68, 268-277, 2014 | 52 | 2014 |
Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure M Dagnell, PE Pace, Q Cheng, J Frijhoff, A Östman, ESJ Arnér, ... Journal of Biological Chemistry 292 (35), 14371-14380, 2017 | 41 | 2017 |
Clinical relevance of cyclic GMP modulators: a translational success story of network pharmacology JM Oettrich, VT Dao, J Frijhoff, PWM Kleikers, AI Casas, AJ Hobbs, ... Clinical Pharmacology & Therapeutics 99 (4), 360-362, 2016 | 18 | 2016 |
Effects of epigenetic modificators in combination with small molecule inhibitors of receptor tyrosine kinases on medulloblastoma growth AM Marino, J Frijhoff, R Calero, N Baryawno, A Östman, JI Johnsen Biochemical and Biophysical Research Communications 450 (4), 1600-1605, 2014 | 12 | 2014 |
Protein nitration is a physiological regulator of cardiac lactate dehydrogenase active site loop mobility and activity C Nogales, J Frijhoff, D Thoenges, RB Sessions, A Sickmann, ... bioRxiv, 348789, 2018 | 3 | 2018 |
Thioredoxin Reductase 1 Directly Protects Protein Tyrosine Phosphatase 1B from Inactivation by H2O2 M Dagnell, P Pace, Q Cheng, J Frijhoff, A Östman, E Arnér, M Hampton, ... Free Radical Biology and Medicine 100, S47, 2016 | | 2016 |
MECHANISMS UNDERLYING THE PRO-TUMORIGENIC EFFECT OF CXCL14-EXPRESSING CANCER-ASSOCIATED FIBROBLASTS M Augsten, E Sjoberg, O Frings, J Frijhoff, A Ostman ANTICANCER RESEARCH 34 (10), 5821-5822, 2014 | | 2014 |
Protein Tyrosine Phosphatases: Taking a'redoxionist'Look at PDGFR Signaling J Frijhoff PQDT-Global, 2014 | | 2014 |