Recent Advances and Perspectives in Cancer Drug Design LG MAGALHAES, LLG FERREIRA, AD ANDRICOPULO Anais da Academia Brasileira de Ciências 90 (1), 1233-1250, 2018 | 65 | 2018 |
Discovery of potent, reversible, and competitive cruzain inhibitors with trypanocidal activity: a structure-based drug design approach ML de Souza, C de Oliveira Rezende Junior, RS Ferreira, ... Journal of Chemical Information and Modeling 60 (2), 1028-1041, 2019 | 44 | 2019 |
Inhibition of Breast Cancer Cell Migration by Cyclotides Isolated from Pombalia calceolaria MEF Pinto, JZG Najas, LG Magalhães, AF Bobey, JN Mendonça, ... Journal of natural products 81 (5), 1203-1208, 2018 | 43 | 2018 |
The Effectiveness of Natural Diarylheptanoids against Trypanosoma cruzi: Cytotoxicity, Ultrastructural Alterations and Molecular Modeling Studies V Sueth-Santiago, JBB Moraes, ES Sobral Alves, MA Vannier-Santos, ... PLoS One 11 (9), e0162926, 2016 | 30 | 2016 |
Structure-Based and Molecular Modeling Studies for the Discovery of Cyclic Imides as Reversible Cruzain Inhibitors With Potent Anti-Trypanosoma cruzi Activity RAA Ferreira, I Pauli, TS Sampaio, ML de Souza, LLG Ferreira, ... Frontiers in Chemistry 7, 798, 2019 | 27 | 2019 |
Discovery of a series of acridinones as mechanism-based tubulin assembly inhibitors with anticancer activity LG Magalhaes, FB Marques, MB da Fonseca, KR Rogerio, CS Graebin, ... PloS one 11 (8), e0160842, 2016 | 16 | 2016 |
Synthesis of chalcones derived from 1-naphthylacetophenone and evaluation of their cytotoxic and apoptotic effects in acute leukemia cell lines AV Jacques, NM Stefanes, LO Walter, DM Perondi, F da Luz Efe, ... Bioorganic Chemistry 116, 105315, 2021 | 11 | 2021 |
A Myristoyl Amide Derivative of Doxycycline Potently Targets Cancer Stem Cells (CSCs) and Prevents Spontaneous Metastasis, Without Retaining Antibiotic Activity FSMPL Béla Ózsvári, Luma G. Magalhães, Joe Latimer, Jussi Kangasmetsa Frontiers in Oncology 10, 2020 | 11 | 2020 |
Semisynthesis of new aphidicolin derivatives with high activity against Trypanosoma cruzi GB Santos, R Krogh, LG Magalhaes, AD Andricopulo, MT Pupo, ... Bioorganic & medicinal chemistry letters 26 (4), 1205-1208, 2016 | 11 | 2016 |
Multiparameter Optimization of Trypanocidal Cruzain Inhibitors with In Vivo Activity and Favorable Pharmacokinetics I Pauli, CO Rezende Junior, BW Slafer, MA Dessoy, ML de Souza, ... Frontiers in Pharmacology, 3570, 0 | 8 | |
Combined “omics” techniques for targeted investigation on CYP450 roles during bioactive quinonemethide triterpenes biosynthesis: Maytenus spp. case study DP Pavarini, MMS Biasioli, TM de Souza Moreira, LG Magalhaes, ... Planta Medica 82 (S 01), P213, 2016 | 1 | 2016 |
Planejamento e caracterização de moduladores da proteína tubulina candidatos a fármacos para o tratamento do câncer LG Magalhães Universidade de São Paulo, 0 | 1* | |
SELECTIVE CDK 4/6 INHIBITOR CANCER THERAPEUTICS MP Lisanti, F Sotgia, J Kangasmetsa, LG Magalhães US Patent App. 17/785,239, 2023 | | 2023 |
SELECTIVE CDK4/6 INHIBITOR CANCER THERAPEUTICS MP Lisanti, F Sotgia, J Kangasmetsa, LG Magalhães US Patent App. 17/786,189, 2023 | | 2023 |
Carbamoyl Imidazoles As Potent, Reversible and Competitive Cruzain Inhibitors with in vitro and in vivo Trypanocidal Activity: A Structure-Based Drug Design … ML de Souza, COR Junior, RS Ferreira, RM Espinoza Chávez, L Ferreira, ... Reversible and Competitive Cruzain Inhibitors with in vitro and in vivo …, 2019 | | 2019 |
Identificação e caracterização de novos agentes moduladores de microtúbulos com propriedades antitumorais CT Martins, EMG Silva, LG Magalhães, EB Mass, D Russosky, ... Resumos, 2019 | | 2019 |
Carbamoylimidazoles as potent cruzain inhibitors with in vitro and in vivo trypanocidal activity: a structure-based drug design approach C Rezende Junior, FC Cruz, LLG Ferreira, LG Magalhães, ... Anais eletrônicos, 2019 | | 2019 |
Otimização da síntese, separação enantiomérica e determinação da configuração de enantiômeros de acridinona com atividade anticâncer MB Fonseca, CS Grebin, LG Magalhães, RC Gomes, FAS Coelho, ... Programa e Resumos, 2019 | | 2019 |
Optimization of a protocol for the virtual screening of a series of small-molecules ligands of the tubulin colchicine binding site DL Palomino-Salcedo, LG Magalhães, G Oliva, AD Andricopulo Programa e Resumos, 2019 | | 2019 |
Antitrypanosomal aminobenzimidazoles: hit to lead expansion of new chemical entities against Trypanosoma cruzi and Leishmania infantum RAA Ferreira, CR Oliveira Junior, PG Martinez, BM Soares, P Koovits, ... Anais eletrônicos, 2019 | | 2019 |