Designing of novel carbonic anhydrase inhibitors and activators CT Supuran, D Vullo, G Manole, A Casini, A Scozzafava Current Medicinal Chemistry-Cardiovascular & Hematological Agents 2 (1), 49-68, 2004 | 193 | 2004 |
Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1, 3, 4-thiadiazole-and 1, 2, 4 … GL Almajan, A Innocenti, L Puccetti, G Manole, S Barbuceanu, I Saramet, ... Bioorganic & medicinal chemistry letters 15 (9), 2347-2352, 2005 | 110 | 2005 |
Inhibition of the β-class carbonic anhydrases from Mycobacterium tuberculosis with carboxylic acids A Maresca, D Vullo, A Scozzafava, G Manole, CT Supuran Journal of enzyme inhibition and medicinal chemistry 28 (2), 392-396, 2013 | 91 | 2013 |
Carbonic anhydrase inhibitors. V: Pyrylium salts in the synthesis of isozyme-specific inhibitors CT Supuran, G Manole, A Dinculescu, A Schiketanz, MD Gheorghiu, ... Journal of pharmaceutical sciences 81 (7), 716-719, 1992 | 58 | 1992 |
Carbonic anhydrase inhibitors. Part 11. Coordination compounds of heterocyclic sulfonamides with lanthanides are potent inhibitors of isozymes I and II CT Supuran, M Andruh, G Manole Journal of inorganic biochemistry 49 (2), 97-103, 1993 | 43 | 1993 |
Carbonic-Anhydrase Inhibitors. 13. Complex-Type Mechanism-Based Inhibitors CT Supuran Revue Roumaine de Chimie 37 (7), 849-855, 1992 | 35 | 1992 |
CARBONIC-ANHYDRASE INHIBITORS. 15. COMPLEX INHIBITORS CONTAINING MAIN-GROUP AND TRANSITIONAL DIVALENT-CATIONS CT Supuran, G Loloiu, G Manole Revue Roumaine de Chimie 38 (1), 115-122, 1993 | 23 | 1993 |
Myeloperoxidase, a possible biomarker for the early diagnosis of cardiac diastolic dysfunction with preserved ejection fraction BI Coculescu, GV Dincă, C Bălăeţ, G Manole, M Bălăeţ, CM Stocheci Journal of Enzyme Inhibition and Medicinal Chemistry 33 (1), 1292-1298, 2018 | 20 | 2018 |
Carbonic anhydrase activators: Activation of the β-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids A Innocenti, W Leewattanapasuk, G Manole, A Scozzafava, ... Bioorganic & Medicinal Chemistry Letters 20 (5), 1701-1704, 2010 | 19 | 2010 |
Protease inhibitors: Part 12. Synthesis of potent matrix metalloproteinase and bacterial collagenase inhibitors incorporating sulfonylated N-4-nitrobenzyl-β-alanine hydroxamate … A Scozzafava, MA Ilies, G Manole, CT Supuran European journal of pharmaceutical sciences 11 (1), 69-79, 2000 | 18 | 2000 |
CARBONIC-ANHYDRASE ACTIVATORS. 2. AMINO-ACIDS AND SOME OF THEIR DERIVATIVES MAY ACT AS POTENT ENZYME ACTIVATORS CT Supuran, A Dinculescu, G Manole, F Savan, I Puscas, AT Balaban REVUE ROUMAINE DE CHIMIE 36 (8), 937-946, 1991 | 18 | 1991 |
Osteopontin–a biomarker of disease, but also of stage stratification of the functional myocardial contractile deficit by chronic ischaemic heart disease BI Coculescu, G Manole, GV Dincă, EC Coculescu, C Berteanu, ... Journal of Enzyme Inhibition and Medicinal Chemistry 34 (1), 783-788, 2019 | 17 | 2019 |
Burning mouth syndrome: controversial place as a symptom of Oro-dental pathology PVL Coculescu E.C., Manole Gh., Coculescu B.I. J. Med. Life., 8 (Spec Issue), 34-37, 2015 | 17 | 2015 |
Molecular processes in the streptokinase thrombolytic therapy C Capitanescu, AM Macovei Oprescu, D Ionita, GV Dinca, C Turculet, ... Journal of enzyme inhibition and medicinal chemistry 31 (6), 1411-1414, 2016 | 16 | 2016 |
Lipoprotein-associated phospholipase A2 (Lp-PLA2)–possible diagnostic and risk biomarker in chronic ischaemic heart disease A Diaconu, BI Coculescu, G Manole, H Vultur, EC Coculescu, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 68-73, 2021 | 15 | 2021 |
Serum concentration of hsCRP-possible marker for therapy evaluation in left ventricular dysfunction with preserved ejection fraction BI Coculescu, GV Dinca, G Manole, VL Purcarea, AM Oproiu, ... Rev. Chim.(Bucharest) 69, 2885-990, 2018 | 14 | 2018 |
Gamma-glutamyltransferase, possible novel biomarker in colon diverticulosis: a case-control study C Bălăeţ, BI Coculescu, G Manole, M Bălăeţ, GV Dincă Journal of enzyme inhibition and medicinal chemistry 33 (1), 428-432, 2018 | 14 | 2018 |
Carbonic-anhydrase inhibitors. 12. Lanthanide complexes with acetazolamide as dual inhibitors CT Supuran, G Manole, I Manzatu Revue Roumaine de Chimie 37 (6), 739-744, 1992 | 14 | 1992 |
1, 3, 4-Thiadiazole derivatives. 1. Zn (II) and Hg (II) coordination-compounds of 2-amino-5-mercapto-1, 3, 4-thiadiazole as enzyme-inhibitors M Brezeanu, R Olar, G Manole, CT Supuran REVUE ROUMAINE DE CHIMIE 37 (4), 425-431, 1992 | 12 | 1992 |
Carbonic anhydrase inhibitors. Part 3. Relations between chemical structure of inhibitors and activators I Puscas, CT Supuran, G Manole Revue Roumaine de Chimie 35, 683-689, 1990 | 11 | 1990 |