| In vitro activation of coagulation by human neutrophil DNA and histone proteins but not neutrophil extracellular traps DF Noubouossie, MF Whelihan, YB Yu, E Sparkenbaugh, R Pawlinski, ... Blood, The Journal of the American Society of Hematology 129 (8), 1021-1029, 2017 | 234 | 2017 |
| Homogeneous low-molecular-weight heparins with reversible anticoagulant activity Y Xu, C Cai, K Chandarajoti, PH Hsieh, L Li, TQ Pham, EM Sparkenbaugh, ... Nature chemical biology 10 (4), 248-250, 2014 | 214 | 2014 |
| Interplay between coagulation and vascular inflammation in sickle cell disease E Sparkenbaugh, R Pawlinski British Journal of Haematology 162 (1), 3-14, 2013 | 186 | 2013 |
| Intrinsic versus idiosyncratic drug-induced hepatotoxicity—two villains or one? RA Roth, PE Ganey Journal of Pharmacology and Experimental Therapeutics 332 (3), 692-697, 2010 | 186 | 2010 |
| Idiosyncratic drug-induced liver injury and the role of inflammatory stress with an emphasis on an animal model of trovafloxacin hepatotoxicity PJ Shaw, PE Ganey, RA Roth Toxicological Sciences 118 (1), 7-18, 2010 | 149 | 2010 |
| Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease EM Sparkenbaugh, P Chantrathammachart, J Mickelson, J Van Ryn, ... Blood, The Journal of the American Society of Hematology 123 (11), 1747-1756, 2014 | 128 | 2014 |
| Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease P Chantrathammachart, N Mackman, E Sparkenbaugh, JG Wang, ... Blood, The Journal of the American Society of Hematology 120 (3), 636-646, 2012 | 115 | 2012 |
| Novel role for the AnxA1-Fpr2/ALX signaling axis as a key regulator of platelet function to promote resolution of inflammation EY Senchenkova, J Ansari, F Becker, SA Vital, Z Al-Yafeai, ... Circulation 140 (4), 319-335, 2019 | 109 | 2019 |
| Synthetic oligosaccharides can replace animal-sourced low–molecular weight heparins Y Xu, K Chandarajoti, X Zhang, V Pagadala, W Dou, DM Hoppensteadt, ... Science translational medicine 9 (406), eaan5954, 2017 | 104 | 2017 |
| Excess of heme induces tissue factor-dependent activation of coagulation in mice EM Sparkenbaugh, P Chantrathammachart, S Wang, W Jonas, ... haematologica 100 (3), 308, 2015 | 91 | 2015 |
| Design of anti-inflammatory heparan sulfate to protect against acetaminophen-induced acute liver failure K Arnold, Y Xu, EM Sparkenbaugh, M Li, X Han, X Zhang, K Xia, ... Science translational medicine 12 (535), eaav8075, 2020 | 81 | 2020 |
| Bacterial-and viral-induced inflammation increases sensitivity to acetaminophen hepatotoxicity JF Maddox, CJ Amuzie, M Li, SW Newport, E Sparkenbaugh, CF Cuff, ... Journal of Toxicology and Environmental Health, Part A 73 (1), 58-73, 2009 | 70 | 2009 |
| Hepatotoxic interaction of sulindac with lipopolysaccharide: role of the hemostatic system W Zou, SS Devi, E Sparkenbaugh, HS Younis, RA Roth, PE Ganey Toxicological sciences 108 (1), 184-193, 2009 | 70 | 2009 |
| Red blood cells modulate structure and dynamics of venous clot formation in sickle cell disease C Faes, A Ilich, A Sotiaux, EM Sparkenbaugh, MW Henderson, L Buczek, ... Blood, The Journal of the American Society of Hematology 133 (23), 2529-2541, 2019 | 62 | 2019 |
| Sulindac metabolism and synergy with tumor necrosis factor-α in a drug-inflammation interaction model of idiosyncratic liver injury W Zou, KM Beggs, EM Sparkenbaugh, AD Jones, HS Younis, RA Roth, ... Journal of Pharmacology and Experimental Therapeutics 331 (1), 114-121, 2009 | 58 | 2009 |
| Prothrombotic aspects of sickle cell disease E Sparkenbaugh, R Pawlinski Journal of Thrombosis and Haemostasis 15 (7), 1307-1316, 2017 | 56 | 2017 |
| The role of hypoxia-inducible factor-1α in acetaminophen hepatotoxicity EM Sparkenbaugh, Y Saini, KK Greenwood, JJ LaPres, JP Luyendyk, ... Journal of Pharmacology and Experimental Therapeutics 338 (2), 492-502, 2011 | 54 | 2011 |
| Protease activated receptor-2 contributes to heart failure S Antoniak, EM Sparkenbaugh, M Tencati, M Rojas, N Mackman, ... PloS one 8 (11), e81733, 2013 | 53 | 2013 |
| Trovafloxacin enhances TNF-induced inflammatory stress and cell death signaling and reduces TNF clearance in a murine model of idiosyncratic hepatotoxicity PJ Shaw, KM Beggs, EM Sparkenbaugh, CM Dugan, PE Ganey, RA Roth Toxicological sciences 111 (2), 288-301, 2009 | 51 | 2009 |
| Hepatocyte tissue factor contributes to the hypercoagulable state in a mouse model of chronic liver injury PE Rautou, K Tatsumi, S Antoniak, AP Owens III, E Sparkenbaugh, ... Journal of hepatology 64 (1), 53-59, 2016 | 49 | 2016 |
