The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease D Chabas, SE Baranzini, D Mitchell, CCA Bernard, SR Rittling, ... Science 294 (5547), 1731-1735, 2001 | 1085 | 2001 |
Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine MV Karpuj, MW Becher, JE Springer, D Chabas, S Youssef, R Pedotti, ... Nature medicine 8 (2), 143-149, 2002 | 461 | 2002 |
Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington’s disease brain nuclei MV Karpuj, H Garren, H Slunt, DL Price, J Gusella, MW Becher, ... Proceedings of the National Academy of Sciences 96 (13), 7388-7393, 1999 | 300 | 1999 |
DNA methylation analysis of the autistic brain reveals multiple dysregulated biological pathways S Nardone, D Sharan Sams, E Reuveni, D Getselter, O Oron, M Karpuj, ... Translational psychiatry 4 (9), e433-e433, 2014 | 263 | 2014 |
An unexpected version of horror autotoxicus: anaphylactic shock to a self-peptide R Pedotti, D Mitchell, J Wedemeyer, M Karpuj, D Chabas, EM Hattab, ... Nature immunology 2 (3), 216-222, 2001 | 228 | 2001 |
Dysbiosis of microbiome and probiotic treatment in a genetic model of autism spectrum disorders L Tabouy, D Getselter, O Ziv, M Karpuj, T Tabouy, I Lukic, R Maayouf, ... Brain, behavior, and immunity 73, 310-319, 2018 | 177 | 2018 |
Suppressive immunization with DNA encoding a self-peptide prevents autoimmune disease: modulation of T cell costimulation PJ Ruiz, H Garren, IU Ruiz, DL Hirschberg, LVT Nguyen, MV Karpuj, ... The Journal of Immunology 162 (6), 3336-3341, 1999 | 144 | 1999 |
A novel putative neuropeptide receptor expressed in neural tissue, including sensory epithelia M Tal, DA Ammar, M Karpuj, V Krizhanovsky, M Naim, DA Thompson Biochemical and biophysical research communications 209 (2), 752-759, 1995 | 125 | 1995 |
Microbial epitopes act as altered peptide ligands to prevent experimental autoimmune encephalomyelitis PJ Ruiz, H Garren, DL Hirschberg, AM Langer-Gould, M Levite, ... The Journal of experimental medicine 189 (8), 1275-1284, 1999 | 82 | 1999 |
Evidence for a role for transglutaminase in Huntington's disease and the potential therapeutic implications MV Karpuj, MW Becher, L Steinman Neurochemistry international 40 (1), 31-36, 2002 | 78 | 2002 |
Idiotypic immunization induces immunity to mutated p53 and tumor rejection PJ Ruiz, R Wolkowicz, A Waisman, DL Hirschberg, P Carmi, N Erez, ... Nature medicine 4 (6), 710-712, 1998 | 67 | 1998 |
Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers K Takai, AP Drain, DA Lawson, LE Littlepage, M Karpuj, K Kessenbrock, ... Genes & development 32 (3-4), 244-257, 2018 | 64 | 2018 |
Tissue Transglutaminase contributes to experimental multiple sclerosis pathogenesis and clinical outcome by promoting macrophage migration ME van Strien, HE de Vries, NL Chrobok, JGJM Bol, JJP Breve, ... Brain, behavior, and immunity 50, 141-154, 2015 | 38 | 2015 |
Cyclosporin-A-induced prion protein aggresomes are dynamic quality-control cellular compartments T Ben-Gedalya, R Lyakhovetsky, Y Yedidia, M Bejerano-Sagie, ... Journal of cell science 124 (11), 1891-1902, 2011 | 38 | 2011 |
Phosphorothioate Oligonucleotides Reduce PrPSc Levels and Prion Infectivity in Cultured Cells MV Karpuj, K Giles, S Gelibter-Niv, MR Scott, VR Lingappa, FC Szoka, ... Molecular medicine 13, 190-198, 2007 | 35 | 2007 |
Multiple sclerosis: a polygenic disease involving epistatic interactions, germline rearrangements and environmental effects MV Karpuj, L Steinman, JR Oksenberg Neurogenetics 1, 21-28, 1997 | 35 | 1997 |
Modulation of cellular CpG DNA methylation by Kaposi's sarcoma-associated herpesvirus G Journo, C Tushinsky, A Shterngas, N Avital, Y Eran, MV Karpuj, ... Journal of virology 92 (16), 10.1128/jvi. 00008-18, 2018 | 26 | 2018 |
Detection of gene mutations and gene–gene fusions in circulating cell‐free DNA of glioblastoma patients: an avenue for clinically relevant diagnostic analysis V Palande, T Siegal, R Detroja, A Gorohovski, R Glass, C Flueh, ... Molecular Oncology 16 (10), 2098-2114, 2022 | 24 | 2022 |
The multifaceted role of transglutaminase in neurodegeneration M Karpuj, L Steinman Amino Acids 26, 373-379, 2004 | 15 | 2004 |
Biochemical and biophysical characterization of cell-free synthesized Rift Valley fever virus nucleoprotein capsids enables in vitro screening to identify novel antivirals S Broce, L Hensley, T Sato, J Lehrer-Graiwer, C Essrich, KJ Edwards, ... Biology Direct 11, 1-14, 2016 | 9 | 2016 |