Determinants of enzyme thermostability observed in the molecular structure of Thermus aquaticus D-glyceraldehyde-3-phosphate dehydrogenase at 2.5 Å resolution JJ Tanner, RM Hecht, KL Krause Biochemistry 35 (8), 2597-2609, 1996 | 305 | 1996 |
Emergence of macrolide resistance during treatment of pneumococcal pneumonia DM Musher, ME Dowell, VD Shortridge, RK Flamm, JH Jorgensen, ... New England Journal of Medicine 346 (8), 630-631, 2002 | 226 | 2002 |
2.5 Å structure of aspartate carbamoyltransferase complexed with the bisubstrate analog N-(phosphonacetyl)-L-aspartate KL Krause, KW Volz, WN Lipscomb Journal of molecular biology 193 (3), 527-553, 1987 | 226 | 1987 |
Severe diabetes associated with protease inhibitor therapy. F Visnegarwala, KL Krause, DM Musher | 192 | 1997 |
Flavin Reductase P: Structure of a Dimeric Enzyme That Reduces Flavin, JJ Tanner, B Lei, SC Tu, KL Krause Biochemistry 35 (42), 13531-13539, 1996 | 141 | 1996 |
2.1 Å structure of Serratia endonuclease suggests a mechanism for binding to double-stranded DNA MD Miller, J Tanner, M Alpaugh, MJ Benedik, KL Krause Nature structural biology 1 (7), 461-468, 1994 | 139 | 1994 |
Analysis of the mechanism of the Serratia nuclease using site-directed mutagenesis P Friedhoff, B Kolmes, O Gimadutdinow, W Wende, KL Krause, A Pingoud Nucleic acids research 24 (14), 2632-2639, 1996 | 136 | 1996 |
Structure at 2.9-A resolution of aspartate carbamoyltransferase complexed with the bisubstrate analogue N-(phosphonacetyl)-L-aspartate. KL Krause, KW Volz, WN Lipscomb Proceedings of the National Academy of Sciences 82 (6), 1643-1647, 1985 | 132 | 1985 |
Characterization of the alanine racemases from two mycobacteria U Strych, RL Penland, M Jimenez, KL Krause, MJ Benedik FEMS microbiology letters 196 (2), 93-98, 2001 | 131 | 2001 |
Chemical Generation of C602- and Electron Transfer Mechanism for the Reactions with Alkyl Bromides R Subramanian, KM Kadish, MN Vijayashree, X Gao, MT Jones, ... The Journal of Physical Chemistry 100 (40), 16327-16335, 1996 | 127 | 1996 |
Spacer capture and integration by a type IF Cas1–Cas2-3 CRISPR adaptation complex RD Fagerlund, ME Wilkinson, O Klykov, A Barendregt, FG Pearce, ... Proceedings of the National Academy of Sciences 114 (26), E5122-E5128, 2017 | 116 | 2017 |
The 1.9 Å Crystal Structure of Alanine Racemase from Mycobacterium tuberculosis Contains a Conserved Entryway into the Active Site, P LeMagueres, H Im, J Ebalunode, U Strych, MJ Benedik, JM Briggs, ... Biochemistry 44 (5), 1471-1481, 2005 | 116 | 2005 |
The active site of Serratia endonuclease contains a conserved magnesium-water cluster MD Miller, J Cai, KL Krause Journal of molecular biology 288 (5), 975-987, 1999 | 115 | 1999 |
A similar active site for non–specific and specific endonucleases P Friedhoff, I Franke, G Meiss, W Wende, KL Krause, A Pingoud Nature structural biology 6 (2), 112-113, 1999 | 84 | 1999 |
Characterization of the Alanine Racemases from Pseudomonas aeruginosa PAO1 U Strych, HC Huang, KL Krause, MJ Benedik Current microbiology 41, 290-294, 2000 | 78 | 2000 |
The catalytic mechanism of Escherichia coli aspartate carbamoyltransferase: a molecular modelling study JE Gouaux, KL Krause, WN Lipscomb Biochemical and biophysical research communications 142 (3), 893-897, 1987 | 71 | 1987 |
The Alanine Racemase of Mycobacterium smegmatis Is Essential for Growth in the Absence of d-Alanine DL Milligan, SL Tran, U Strych, GM Cook, KL Krause Journal of bacteriology 189 (22), 8381-8386, 2007 | 69 | 2007 |
Identification of the Serratia endonuclease dimer: Structural basis and implications for catalysis MD Miller, KL Krause Protein science 5 (1), 24-33, 1996 | 69 | 1996 |
Experience with commercial area detectors: abuyer's' perspective KL Krause, GN Phillips Journal of applied crystallography 25 (2), 146-154, 1992 | 64 | 1992 |
New Classes of Alanine Racemase Inhibitors Identified by High-Throughput Screening Show Antimicrobial Activity against Mycobacterium tuberculosis KG Anthony, U Strych, KR Yeung, CS Shoen, O Perez, KL Krause, ... PloS one 6 (5), e20374, 2011 | 60 | 2011 |