Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis RC Agís-Balboa, G Pinna, A Zhubi, E Maloku, M Veldic, E Costa, ... Proceedings of the National Academy of Sciences 103 (39), 14602-14607, 2006 | 427 | 2006 |
Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder AM Rasmusson, G Pinna, P Paliwal, D Weisman, C Gottschalk, ... Biological psychiatry 60 (7), 704-713, 2006 | 311 | 2006 |
Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice L Tremolizzo, MS Doueiri, E Dong, DR Grayson, J Davis, G Pinna, ... Biological psychiatry 57 (5), 500-509, 2005 | 289 | 2005 |
Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake G Pinna, E Costa, A Guidotti Psychopharmacology 186, 362-372, 2006 | 288 | 2006 |
Decreased corticolimbic allopregnanolone expression during social isolation enhances contextual fear: a model relevant for posttraumatic stress disorder F Pibiri, M Nelson, A Guidotti, E Costa, G Pinna Proceedings of the National Academy of Sciences 105 (14), 5567-5572, 2008 | 267 | 2008 |
In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine G Pinna, E Dong, K Matsumoto, E Costa, A Guidotti Proceedings of the National Academy of Sciences 100 (4), 2035-2040, 2003 | 242 | 2003 |
Epigenetic GABAergic targets in schizophrenia and bipolar disorder A Guidotti, J Auta, Y Chen, JM Davis, E Dong, DP Gavin, DR Grayson, ... Neuropharmacology 60 (7-8), 1007-1016, 2011 | 229 | 2011 |
The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5α-dihydroprogesterone in psychiatric disorders A Guidotti, E Dong, K Matsumoto, G Pinna, AM Rasmusson, E Costa Brain Research Reviews 37 (1-3), 110-115, 2001 | 193 | 2001 |
Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice RC Agís-Balboa, G Pinna, F Pibiri, B Kadriu, E Costa, A Guidotti Proceedings of the National Academy of Sciences 104 (47), 18736-18741, 2007 | 188 | 2007 |
Social isolation stress-induced aggression in mice: a model to study the pharmacology of neurosteroidogenesis K Matsumoto, G Pinna, G Puia, A Guidotti, E Costa Stress 8 (2), 85-93, 2005 | 179 | 2005 |
SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake G Pinna, E Costa, A Guidotti Current opinion in pharmacology 9 (1), 24-30, 2009 | 171 | 2009 |
GABAA receptor neurotransmission dysfunction in a mouse model of social isolation-induced stress: Possible insights into a non-serotonergic mechanism of action … K Matsumoto, G Puia, E Dong, G Pinna Stress 10 (1), 3-12, 2007 | 158 | 2007 |
Brain allopregnanolone regulates the potency of the GABAA receptor agonist muscimol G Pinna, V Uzunova, K Matsumoto, G Puia, JM Mienville, E Costa, ... Neuropharmacology 39 (3), 440-448, 2000 | 150 | 2000 |
Permissive role of brain allopregnanolone content in the regulation of pentobarbital-induced righting reflex loss K Matsumoto, V Uzunova, G Pinna, K Taki, DP Uzunov, H Watanabe, ... Neuropharmacology 38 (7), 955-963, 1999 | 136 | 1999 |
Neurosteroid biosynthesis regulates sexually dimorphic fear and aggressive behavior in mice G Pinna, RC Agis-Balboa, F Pibiri, M Nelson, A Guidotti, E Costa Neurochemical research 33, 1990-2007, 2008 | 133 | 2008 |
Neurosteroid biosynthesis down‐regulation and changes in GABAA receptor subunit composition: a biomarker axis in stress‐induced cognitive and emotional … A Locci, G Pinna British journal of pharmacology 174 (19), 3226-3241, 2017 | 129 | 2017 |
Phenolic and tyrosyl ring iodothyronine deiodination and thyroid hormone concentrations in the human central nervous system A Campos-Barros, T Hoell, A Musa, S Sampaolo, G Stoltenburg, G Pinna, ... The Journal of Clinical Endocrinology & Metabolism 81 (6), 2179-2185, 1996 | 127 | 1996 |
Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior G Pinna, E Costa, A Guidotti Proceedings of the National Academy of Sciences 102 (6), 2135-2140, 2005 | 122 | 2005 |
S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis A Guidotti, W Ruzicka, DR Grayson, M Veldic, G Pinna, JM Davis, E Costa Neuroreport 18 (1), 57-60, 2007 | 121 | 2007 |
Chronic intermittent ethanol (CIE) administration in rats decreases levels of neurosteroids in hippocampus, accompanied by altered behavioral responses to neurosteroids and … E Cagetti, G Pinna, A Guidotti, K Baicy, RW Olsen Neuropharmacology 46 (4), 570-579, 2004 | 115 | 2004 |