Discovery of a novel, first-in-class, orally bioavailable azaindole inhibitor (VX-787) of influenza PB2 MP Clark, MW Ledeboer, I Davies, RA Byrn, SM Jones, E Perola, A Tsai, ... Journal of medicinal chemistry 57 (15), 6668-6678, 2014 | 222 | 2014 |
Discovery of a potent and selective prostaglandin D2 receptor antagonist,[(3 R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1, 2, 3, 4-tetrahydrocyclopenta [b] indol-3-yl … CF Sturino, G O'Neill, N Lachance, M Boyd, C Berthelette, M Labelle, L Li, ... Journal of medicinal chemistry 50 (4), 794-806, 2007 | 204 | 2007 |
Battery charger for cellular phone, having speaker SY Yi US Patent 6,509,716, 2003 | 81 | 2003 |
Vehicle lamp housing R Woolley, E Lucas, D Carbis, D Park, M Boyd US Patent App. 29/330,138, 2009 | 59 | 2009 |
Application of the photoredox coupling of trifluoroborates and aryl bromides to analog generation using continuous flow TJ DeLano, UK Bandarage, N Palaychuk, J Green, MJ Boyd The Journal of Organic Chemistry 81 (24), 12525-12531, 2016 | 52 | 2016 |
Court MP Clark, MW Ledeboer, I Davies, RA Byrn, SM Jones, E Perola, A Tsai, ... JJ, Deng, H., Duffy, JP, Dorsch, WA, Farmer, LJ, Gao, H., Gu, W., Jackson, K …, 2014 | 52 | 2014 |
Cyclopentanoindoles, compositions containing such compounds and methods of treatment M Labelle, C Sturino, B Roy, C Berthelette, M Boyd, N LaChance, ... US Patent 6,410,583, 2002 | 52 | 2002 |
C–H Functionalization of heteroarenes using unactivated alkyl halides through visible-light photoredox catalysis under basic conditions NB Bissonnette, MJ Boyd, GD May, S Giroux, P Nuhant The Journal of Organic Chemistry 83 (18), 10933-10940, 2018 | 39 | 2018 |
Discovery of 4-{1-[({1-[4-(trifluoromethyl) benzyl]-1H-indol-7-yl} carbonyl) amino] cyclopropyl} benzoic acid (MF-766), a highly potent and selective EP4 antagonist for … J Colucci, M Boyd, C Berthelette, JF Chiasson, Z Wang, Y Ducharme, ... Bioorganic & Medicinal Chemistry Letters 20 (12), 3760-3763, 2010 | 39 | 2010 |
Stereoselective Synthesis of a Thymine Derivative of (S)-2-Hydroxy-4-(2-aminophenyl)butanoic Acid. A Novel Building Block for the Synthesis of Aromatic Peptidic Nucleic … YS Tsantrizos, JF Lunetta, M Boyd, LD Fader, MC Wilson The Journal of Organic Chemistry 62 (16), 5451-5457, 1997 | 39 | 1997 |
Synthesis of cycloalkyl substituted 7-azaindoles via photoredox nickel dual catalytic cross-coupling in batch and continuous flow N Palaychuk, TJ DeLano, MJ Boyd, J Green, UK Bandarage Organic letters 18 (23), 6180-6183, 2016 | 38 | 2016 |
Generation of Diversity Sets with High sp3 Fraction Using the Photoredox Coupling of Organotrifluoroborates and Organosilicates with Heteroaryl/Aryl Bromides in … KD Raynor, GD May, UK Bandarage, MJ Boyd The Journal of Organic Chemistry 83 (3), 1551-1557, 2018 | 37 | 2018 |
Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors MJ Boyd, UK Bandarage, H Bennett, RR Byrn, I Davies, W Gu, M Jacobs, ... Bioorganic & medicinal chemistry letters 25 (9), 1990-1994, 2015 | 37 | 2015 |
Nickel-catalyzed electrochemical reductive homocouplings of aryl and heteroaryl halides: a useful route to symmetrical biaryls R Rahil, S Sengmany, E Le Gall, E Leonel Synthesis 50 (01), 146-154, 2018 | 35 | 2018 |
Inhibitors of influenza viruses replication PS Charifson, MP Clark, UK Bandarage, RS Bethiel, H Deng, I Davies, ... US Patent App. 13/327,206, 2012 | 34 | 2012 |
A novel series of potent and selective EP4 receptor ligands: Facile modulation of agonism and antagonism MJ Boyd, C Berthelette, JF Chiasson, P Clark, J Colucci, D Denis, Y Han, ... Bioorganic & medicinal chemistry letters 21 (1), 484-487, 2011 | 34 | 2011 |
Backbone modifications of aromatic peptide nucleic acid (APNA) monomers and their hybridization properties with DNA and RNA LD Fader, M Boyd, YS Tsantrizos The Journal of Organic Chemistry 66 (10), 3372-3379, 2001 | 33 | 2001 |
Catalysis of Ester Aminolysis by Cyclodextrins. The Reaction of Alkylamines with p-Nitrophenyl Alkanoates TA Gadosy, MJ Boyd, OS Tee The Journal of Organic Chemistry 65 (21), 6879-6889, 2000 | 32 | 2000 |
Vehicle grille R Woolley, E Lucas, D Carbis, D Park, M Boyd US Patent App. 29/333,100, 2009 | 31 | 2009 |
Vehicle front fender R Woolley, E Lucas, D Carbis, D Park, M Boyd US Patent App. 29/306,435, 2009 | 31 | 2009 |