| Mechanical devices of the spliceosome: motors, clocks, springs, and things JP Staley, C Guthrie Cell 92 (3), 315-326, 1998 | 1491 | 1998 |
| RNA catalyses nuclear pre-mRNA splicing SM Fica, N Tuttle, T Novak, NS Li, J Lu, P Koodathingal, Q Dai, JP Staley, ... Nature 503 (7475), 229-234, 2013 | 421 | 2013 |
| An RNA switch at the 5′ splice site requires ATP and the DEAD box protein Prp28p JP Staley, C Guthrie Molecular cell 3 (1), 55-64, 1999 | 420 | 1999 |
| Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor JYF Chen, L Stands, JP Staley, RR Jackups, LJ Latus, TH Chang Molecular cell 7 (1), 227-232, 2001 | 261 | 2001 |
| The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase EC Small, SR Leggett, AA Winans, JP Staley Molecular cell 23 (3), 389-399, 2006 | 238 | 2006 |
| Autosomal-dominant retinitis pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding of U4/U6 snRNAs C Zhao, DL Bellur, S Lu, F Zhao, MA Grassi, SJ Bowne, LS Sullivan, ... The American Journal of Human Genetics 85 (5), 617-627, 2009 | 217 | 2009 |
| Exon ligation is proofread by the DExD/H-box ATPase Prp22p RM Mayas, H Maita, JP Staley Nature structural & molecular biology 13 (6), 482-490, 2006 | 205 | 2006 |
| A role for ubiquitin in the spliceosome assembly pathway P Bellare, EC Small, X Huang, JA Wohlschlegel, JP Staley, ... Nature structural & molecular biology 15 (5), 444-451, 2008 | 192 | 2008 |
| Assembly of ribosomes and spliceosomes: complex ribonucleoprotein machines JP Staley, JL Woolford Jr Current opinion in cell biology 21 (1), 109-118, 2009 | 185 | 2009 |
| Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs DRE Ranoa, AD Parekh, SP Pitroda, X Huang, T Darga, AC Wong, ... Oncotarget 7 (18), 26496, 2016 | 173 | 2016 |
| Formation of a native‐like subdomain in a partially folded intermediate of bovine pancreatic trypsin inhibitor JP Staley, PS Kim Protein Science 3 (10), 1822-1832, 1994 | 161 | 1994 |
| Spliceosomal DEAH-box ATPases remodel pre-mRNA to activate alternative splice sites DR Semlow, MR Blanco, NG Walter, JP Staley Cell 164 (5), 985-998, 2016 | 156 | 2016 |
| The DEAH box ATPases Prp16 and Prp43 cooperate to proofread 5′ splice site cleavage during pre-mRNA splicing P Koodathingal, T Novak, JA Piccirilli, JP Staley Molecular cell 39 (3), 385-395, 2010 | 136 | 2010 |
| The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis NB Leeds, EC Small, SL Hiley, TR Hughes, JP Staley Molecular and cellular biology 26 (2), 513-522, 2006 | 136 | 2006 |
| Role of a subdomain in the folding of bovine pancreatic trypsin inhibitor JP Staley, PS Kim Nature 344 (6267), 685-688, 1990 | 135 | 1990 |
| Staying on message: ensuring fidelity in pre-mRNA splicing DR Semlow, JP Staley Trends in biochemical sciences 37 (7), 263-273, 2012 | 134 | 2012 |
| U2 toggles iteratively between the stem IIa and stem IIc conformations to promote pre-mRNA splicing AK Hilliker, MA Mefford, JP Staley Genes & development 21 (7), 821-834, 2007 | 130 | 2007 |
| Complete folding of bovine pancreatic trypsin inhibitor with only a single disulfide bond. JP Staley, PS Kim Proceedings of the National Academy of Sciences 89 (5), 1519-1523, 1992 | 129 | 1992 |
| Evidence for a group II intron–like catalytic triplex in the spliceosome SM Fica, MA Mefford, JA Piccirilli, JP Staley Nature structural & molecular biology 21 (5), 464-471, 2014 | 116 | 2014 |
| Spliceosome discards intermediates via the DEAH box ATPase Prp43p RM Mayas, H Maita, DR Semlow, JP Staley Proceedings of the National Academy of Sciences 107 (22), 10020-10025, 2010 | 109 | 2010 |
