Single-cell transcriptome atlas of murine endothelial cells J Kalucka, LPMH de Rooij, J Goveia, K Rohlenova, SJ Dumas, E Meta, ... Cell 180 (4), 764-779. e20, 2020 | 876 | 2020 |
Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy AR Cantelmo, LC Conradi, A Brajic, J Goveia, J Kalucka, A Pircher, ... Cancer cell 30 (6), 968-985, 2016 | 571 | 2016 |
Aberrant methylation of t RNA s links cellular stress to neuro‐developmental disorders S Blanco, S Dietmann, JV Flores, S Hussain, C Kutter, P Humphreys, ... The EMBO journal 33 (18), 2020-2039, 2014 | 537 | 2014 |
Endothelial cell metabolism G Eelen, P de Zeeuw, L Treps, U Harjes, BW Wong, P Carmeliet Physiological reviews 98 (1), 3-58, 2018 | 489 | 2018 |
An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates J Goveia, K Rohlenova, F Taverna, L Treps, LC Conradi, A Pircher, ... Cancer cell 37 (1), 21-36. e13, 2020 | 345 | 2020 |
Basic and therapeutic aspects of angiogenesis updated G Eelen, L Treps, X Li, P Carmeliet Circulation research 127 (2), 310-329, 2020 | 334 | 2020 |
Glioblastoma stem-like cells secrete the pro-angiogenic VEGF-A factor in extracellular vesicles L Treps, R Perret, S Edmond, D Ricard, J Gavard Journal of extracellular vesicles 6 (1), 1359479, 2017 | 252 | 2017 |
Endothelial cell metabolism in health and disease: impact of hypoxia BW Wong, E Marsch, L Treps, M Baes, P Carmeliet The EMBO journal 36 (15), 2187-2203, 2017 | 243 | 2017 |
Quiescent endothelial cells upregulate fatty acid β-oxidation for vasculoprotection via redox homeostasis J Kalucka, L Bierhansl, NV Conchinha, R Missiaen, I Elia, U Brüning, ... Cell metabolism 28 (6), 881-894. e13, 2018 | 221 | 2018 |
Single-cell RNA sequencing maps endothelial metabolic plasticity in pathological angiogenesis K Rohlenova, J Goveia, M García-Caballero, A Subramanian, J Kalucka, ... Cell metabolism 31 (4), 862-877. e14, 2020 | 203 | 2020 |
Impairment of angiogenesis by fatty acid synthase inhibition involves mTOR malonylation U Bruning, F Morales-Rodriguez, J Kalucka, J Goveia, F Taverna, ... Cell metabolism 28 (6), 866-880. e15, 2018 | 191 | 2018 |
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis G Eelen, C Dubois, AR Cantelmo, J Goveia, U Brüning, M DeRan, ... Nature 561 (7721), 63-69, 2018 | 165 | 2018 |
Extracellular vesicle-transported Semaphorin3A promotes vascular permeability in glioblastoma L Treps, S Edmond, E Harford-Wright, EM Galan-Moya, A Schmitt, S Azzi, ... Oncogene 35 (20), 2615-2623, 2016 | 123 | 2016 |
Central role of metabolism in endothelial cell function and vascular disease L Bierhansl, LC Conradi, L Treps, M Dewerchin, P Carmeliet Physiology 32 (2), 126-140, 2017 | 108 | 2017 |
Pharmacological targeting of apelin impairs glioblastoma growth E Harford-Wright, G Andre-Gregoire, KA Jacobs, L Treps, S Le Gonidec, ... Brain 140 (11), 2939-2954, 2017 | 98 | 2017 |
Endothelial cell metabolism: a novel player in atherosclerosis? Basic principles and therapeutic opportunities A Pircher, L Treps, N Bodrug, P Carmeliet Atherosclerosis 253, 247-257, 2016 | 88 | 2016 |
Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation A Le Guelte, EM Galan-Moya, J Dwyer, L Treps, G Kettler, JK Hebda, ... Journal of cell Science 125 (17), 4137-4146, 2012 | 82 | 2012 |
EndoDB: a database of endothelial cell transcriptomics data S Khan, F Taverna, K Rohlenova, L Treps, V Geldhof, L de Rooij, L Sokol, ... Nucleic acids research 47 (D1), D736-D744, 2019 | 81 | 2019 |
Manipulating angiogenesis by targeting endothelial metabolism: hitting the engine rather than the drivers—a new perspective? L Treps, LC Conradi, U Harjes, P Carmeliet Pharmacological Reviews 68 (3), 872-887, 2016 | 57 | 2016 |
Vasculogenic mimicry, a complex and devious process favoring tumorigenesis–interest in making it a therapeutic target L Treps, S Faure, N Clere Pharmacology & therapeutics 223, 107805, 2021 | 55 | 2021 |