Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells M Pepper, JL Linehan, AJ Pagán, T Zell, T Dileepan, PP Cleary, ... Nature immunology 11 (1), 83-89, 2010 | 347 | 2010 |
Tolerance is established in polyclonal CD4+ T cells by distinct mechanisms, according to self-peptide expression patterns D Malhotra, JL Linehan, T Dileepan, YJ Lee, WE Purtha, JV Lu, ... Nature immunology 17 (2), 187-195, 2016 | 233 | 2016 |
T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity RW Nelson, D Beisang, NJ Tubo, T Dileepan, DL Wiesner, K Nielsen, ... Immunity 42 (1), 95-107, 2015 | 183 | 2015 |
Regulatory CD4+ T Cells Recognize Major Histocompatibility Complex Class II Molecule–Restricted Peptide Epitopes of Apolipoprotein B T Kimura, K Kobiyama, H Winkels, K Tse, J Miller, M Vassallo, D Wolf, ... Circulation 138 (11), 1130-1143, 2018 | 155 | 2018 |
Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B100–Reactive CD4+ T-Regulatory Cells D Wolf, T Gerhardt, H Winkels, NA Michel, AB Pramod, Y Ghosheh, ... Circulation 142 (13), 1279-1293, 2020 | 137 | 2020 |
Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells T Dileepan, ED Smith, D Knowland, M Hsu, M Platt, P Bittner-Eddy, ... The Journal of clinical investigation 126 (1), 303-317, 2016 | 135 | 2016 |
Induction of TGF-β1 and TGF-β1–dependent predominant Th17 differentiation by group A streptococcal infection B Wang, T Dileepan, S Briscoe, KA Hyland, J Kang, A Khoruts, PP Cleary Proceedings of the National Academy of Sciences 107 (13), 5937-5942, 2010 | 125 | 2010 |
Robust antigen specific th17 T cell response to group A Streptococcus is dependent on IL-6 and intranasal route of infection T Dileepan, JL Linehan, JJ Moon, M Pepper, MK Jenkins, PP Cleary PLoS pathogens 7 (9), e1002252, 2011 | 119 | 2011 |
Identification of natural regulatory T cell epitopes reveals convergence on a dominant autoantigen JD Leonard, DC Gilmore, T Dileepan, WI Nawrocka, JL Chao, ... Immunity 47 (1), 107-117. e8, 2017 | 83 | 2017 |
High-affinity memory B cells induced by SARS-CoV-2 infection produce more plasmablasts and atypical memory B cells than those primed by mRNA vaccines KA Pape, T Dileepan, AJ Kabage, D Kozysa, R Batres, C Evert, M Matson, ... Cell Reports 37 (2), 2021 | 81 | 2021 |
Salmonella persist in activated macrophages in T cell-sparse granulomas but are contained by surrounding CXCR3 ligand-positioned Th1 cells MF Goldberg, EK Roeske, LN Ward, T Pengo, T Dileepan, DI Kotov, ... Immunity 49 (6), 1090-1102. e7, 2018 | 81 | 2018 |
Generation of Th17 cells in response to intranasal infection requires TGF-β1 from dendritic cells and IL-6 from CD301b+ dendritic cells JL Linehan, T Dileepan, SW Kashem, DH Kaplan, P Cleary, MK Jenkins Proceedings of the National Academy of Sciences 112 (41), 12782-12787, 2015 | 79 | 2015 |
Naive B cells with high-avidity germline-encoded antigen receptors produce persistent IgM+ and transient IgG+ memory B cells KA Pape, RW Maul, T Dileepan, AS Paustian, PJ Gearhart, MK Jenkins Immunity 48 (6), 1135-1143. e4, 2018 | 78 | 2018 |
Human CD18 Is the Functional Receptor for Aggregatibacter actinomycetemcomitans Leukotoxin T Dileepan, SC Kachlany, NV Balashova, J Patel, SK Maheswaran Infection and Immunity 75 (10), 4851-4856, 2007 | 74 | 2007 |
Increased effector memory insulin-specific CD4+ T cells correlate with insulin autoantibodies in patients with recent-onset type 1 diabetes JA Spanier, NL Sahli, JC Wilson, T Martinov, T Dileepan, AL Burrack, ... Diabetes 66 (12), 3051-3060, 2017 | 57 | 2017 |
Mechanisms underlying Mannheimia haemolytica leukotoxin-induced oncosis and apoptosis of bovine alveolar macrophages P Thumbikat, T Dileepan, MS Kannan, SK Maheswaran Microbial pathogenesis 38 (4), 161-172, 2005 | 52 | 2005 |
Immune tolerance of food is mediated by layers of CD4+ T cell dysfunction SW Hong, PD Krueger, KC Osum, T Dileepan, A Herman, DL Mueller, ... Nature 607 (7920), 762-768, 2022 | 49 | 2022 |
Cutting edge: mouse SARS-CoV-2 epitope reveals infection and vaccine-elicited CD8 T cell responses V Joag, S Wijeyesinghe, JM Stolley, CF Quarnstrom, T Dileepan, ... The Journal of Immunology 206 (5), 931-935, 2021 | 43 | 2021 |
Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells PD Krueger, MF Goldberg, SW Hong, KC Osum, RA Langlois, DI Kotov, ... Immunity 54 (4), 687-701. e4, 2021 | 40 | 2021 |
Modulating the quantity of HIV Env-specific CD4 T cell help promotes rare B cell responses in germinal centers JH Lee, JK Hu, E Georgeson, C Nakao, B Groschel, T Dileepan, ... The Journal of experimental medicine 218 (2), 2021 | 40 | 2021 |