Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase S Virdee, Y Ye, DP Nguyen, D Komander, JW Chin Nature chemical biology 6 (10), 750-757, 2010 | 341 | 2010 |
Ubiquitin chain conformation regulates recognition and activity of interacting proteins Y Ye, G Blaser, MH Horrocks, MJ Ruedas-Rama, S Ibrahim, AA Zhukov, ... Nature 492 (7428), 266-270, 2012 | 206 | 2012 |
Polyubiquitin binding and cross‐reactivity in the USP domain deubiquitinase USP21 Y Ye, M Akutsu, F Reyes‐Turcu, RI Enchev, KD Wilkinson, D Komander EMBO reports 12 (4), 350-357, 2011 | 198 | 2011 |
Dissection of USP catalytic domains reveals five common insertion points Y Ye, H Scheel, K Hofmann, D Komander Molecular BioSystems 5 (12), 1797-1808, 2009 | 191 | 2009 |
Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains M Akutsu, Y Ye, S Virdee, JW Chin, D Komander Proceedings of the National Academy of Sciences 108 (6), 2228-2233, 2011 | 154 | 2011 |
The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain M Agromayor, N Soler, A Caballe, T Kueck, SM Freund, MD Allen, ... Structure 20 (3), 414-428, 2012 | 132 | 2012 |
Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein M Iljina, L Tosatto, ML Choi, JC Sang, Y Ye, CD Hughes, CE Bryant, ... Scientific reports 6 (1), 33928, 2016 | 67 | 2016 |
Filamentous aggregates are fragmented by the proteasome holoenzyme R Cliffe, JC Sang, F Kundel, D Finley, D Klenerman, Y Ye Cell reports 26 (8), 2140-2149. e3, 2019 | 55 | 2019 |
Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses JX Meng, Y Zhang, D Saman, AM Haider, S De, JC Sang, K Brown, ... Nature Communications 13 (1), 2692, 2022 | 33 | 2022 |
N-terminal ubiquitination of amyloidogenic proteins triggers removal of their oligomers by the proteasome holoenzyme Y Ye, D Klenerman, D Finley Journal of molecular biology 432 (2), 585-596, 2020 | 33 | 2020 |
Sensitive light-sheet microscopy in multiwell plates using an AFM cantilever A Ponjavic, Y Ye, E Laue, SF Lee, D Klenerman Biomedical Optics Express 9 (12), 5863-5880, 2018 | 24 | 2018 |
Quantitative super-resolution imaging of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies MJ Morten, L Sirvio, H Rupawala, E Mee Hayes, A Franco, C Radulescu, ... Proceedings of the National Academy of Sciences 119 (41), e2205591119, 2022 | 21 | 2022 |
Single-molecule light-sheet microscopy with local nanopipette delivery B Li, A Ponjavic, WH Chen, L Hopkins, C Hughes, Y Ye, C Bryant, ... Analytical Chemistry 93 (8), 4092-4099, 2021 | 15 | 2021 |
A potential mechanism for targeting aggregates with proteasomes and disaggregases in liquid droplets E Mee Hayes, L Sirvio, Y Ye Frontiers in Aging Neuroscience 14, 854380, 2022 | 7 | 2022 |
A General in Vitro Assay for Studying Enzymatic Activities of the Ubiquitin System Y Zuo, BK Chong, K Jiang, D Finley, D Klenerman, Y Ye Biochemistry 59 (7), 851-861, 2020 | 7 | 2020 |
Fluorescent-labelled diubiquitin substrate for a deubiquitinase assay D Komander, Y Ye US Patent App. 13/710,789, 2013 | 2 | 2013 |
Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent inflammatory responses D Klenerman, J Meng, Y Zhang, D Saman, S De, J Sang, K Jiang, ... | 1 | 2021 |
Membrane potential regulates the dynamic localisation of mammalian proteasomes Y Zhang, AH Lippert, JE Lee, AR Carr, A Ponjavic, SF Lee, D Finley, ... bioRxiv, 487702, 2018 | 1 | 2018 |
Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent inflammatory responses Author list JX Meng, Y Zhang, D Saman, S De, JC Sang, K Jiang, J Humphrey, ... | | |