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Thomas M Polasek
Thomas M Polasek
Certara, Princeton, NJ, USA
在 certara.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Drug interactions: principles and practice
BD Snyder, TM Polasek, MP Doogue
1192012
The ABCD of clinical pharmacokinetics
MP Doogue, TM Polasek
Therapeutic advances in drug safety 4 (1), 5-7, 2013
1072013
Mechanism-based inactivation of human cytochrome P4502C8 by drugs in vitro
TM Polasek, DJ Elliot, BC Lewis, JO Miners
Journal of Pharmacology and Experimental Therapeutics 311 (3), 996-1007, 2004
1062004
Perpetrators of pharmacokinetic drug–drug interactions arising from altered cytochrome P450 activity: a criteria‐based assessment
TM Polasek, FPY Lin, JO Miners, MP Doogue
British journal of clinical pharmacology 71 (5), 727-736, 2011
982011
Quantitative prediction of macrolide drug-drug interaction potential from in vitro studies using testosterone as the human cytochrome P4503A substrate
TM Polasek, JO Miners
European journal of clinical pharmacology 62, 203-208, 2006
952006
Drug dosing in renal disease
MP Doogue, TM Polasek
The Clinical Biochemist Reviews 32 (2), 69, 2011
902011
An evaluation of potential mechanism‐based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid
TM Polasek, DJ Elliot, AA Somogyi, EMJ Gillam, BC Lewis, JO Miners
British journal of clinical pharmacology 61 (5), 570-584, 2006
812006
Inhibition of human drug-metabolising cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in vitro by uremic toxins
KJ Barnes, A Rowland, TM Polasek, JO Miners
European journal of clinical pharmacology 70, 1097-1106, 2014
762014
In vitro approaches to investigate mechanism-based inactivation of CYP enzymes
TM Polasek, JO Miners
Expert Opinion on Drug Metabolism & Toxicology 3 (3), 321-329, 2007
692007
Potential drug–drug interactions with direct oral anticoagulants in elderly hospitalized patients
HL Forbes, TM Polasek
Therapeutic advances in drug safety 8 (10), 319-328, 2017
672017
Model-informed precision dosing: background, requirements, validation, implementation, and forward trajectory of individualizing drug therapy
AS Darwich, TM Polasek, JK Aronson, K Ogungbenro, DFB Wright, ...
Annual Review of Pharmacology and Toxicology 61, 225-245, 2021
622021
Precision dosing in clinical medicine: present and future
TM Polasek, S Shakib, A Rostami-Hodjegan
Expert review of clinical pharmacology 11 (8), 743-746, 2018
622018
Predicted metabolic drug clearance with increasing adult age
TM Polasek, F Patel, BP Jensen, MJ Sorich, MD Wiese, MP Doogue
British journal of clinical pharmacology 75 (4), 1019-1028, 2013
562013
Prediction of olanzapine exposure in individual patients using physiologically based pharmacokinetic modelling and simulation
TM Polasek, GT Tucker, MJ Sorich, MD Wiese, T Mohan, ...
British journal of clinical pharmacology 84 (3), 462-476, 2018
542018
In vitro–in vivo extrapolation of CYP2C8-catalyzed paclitaxel 6α-hydroxylation: Effects of albumin on in vitro kinetic parameters and assessment of interindividual variability …
N Wattanachai, TM Polasek, TM Heath, V Uchaipichat, W Tassaneeyakul, ...
European journal of clinical pharmacology 67, 815-824, 2011
502011
Pharmacokinetic evaluation of teriflunomide for the treatment of multiple sclerosis
MD Wiese, A Rowland, TM Polasek, MJ Sorich, C O'Doherty
Expert Opinion on Drug Metabolism & Toxicology 9 (8), 1025-1035, 2013
462013
In vitro characterization of the human liver microsomal kinetics and reaction phenotyping of olanzapine metabolism
P Korprasertthaworn, TM Polasek, MJ Sorich, AJ McLachlan, JO Miners, ...
Drug Metabolism and Disposition 43 (11), 1806-1814, 2015
432015
Time‐dependent inhibition of human drug metabolizing cytochromes P450 by tricyclic antidepressants
TM Polasek, JO Miners
British journal of clinical pharmacology 65 (1), 87-97, 2008
422008
Model‐informed drug development for anti‐infectives: state of the art and future
CR Rayner, PF Smith, D Andes, K Andrews, H Derendorf, LE Friberg, ...
Clinical Pharmacology & Therapeutics 109 (4), 867-891, 2021
342021
What does it take to make model-informed precision dosing common practice? Report from the 1st Asian symposium on precision dosing
TM Polasek, A Rostami-Hodjegan, DS Yim, M Jamei, H Lee, H Kimko, ...
The AAPS journal 21, 1-9, 2019
312019
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