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Graeme Grimes
Graeme Grimes
MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh
在 ed.ac.uk 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Genetic mechanisms of critical illness in COVID-19
E Pairo-Castineira, S Clohisey, L Klaric, AD Bretherick, K Rawlik, D Pasko, ...
Nature 591 (7848), 92-98, 2021
13312021
Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
7412021
Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project
CF Taylor, D Field, SA Sansone, J Aerts, R Apweiler, M Ashburner, ...
Nature biotechnology 26 (8), 889-896, 2008
6202008
Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination
R Eskeland, M Leeb, GR Grimes, C Kress, S Boyle, D Sproul, N Gilbert, ...
Molecular cell 38 (3), 452-464, 2010
6122010
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development
MAM Reijns, B Rabe, RE Rigby, P Mill, KR Astell, LA Lettice, S Boyle, ...
Cell 149 (5), 1008-1022, 2012
5092012
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing
MM Pradeepa, HG Sutherland, J Ule, GR Grimes, WA Bickmore
PLoS genetics 8 (5), e1002717, 2012
3752012
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk
MG Dunlop, SE Dobbins, SM Farrington, AM Jones, C Palles, N Whiffin, ...
Nature genetics 44 (7), 770-776, 2012
2822012
Decreased enhancer-promoter proximity accompanying enhancer activation
NS Benabdallah, I Williamson, RS Illingworth, L Kane, S Boyle, ...
Molecular cell 76 (3), 473-484. e7, 2019
2592019
Histone H3 globular domain acetylation identifies a new class of enhancers
MM Pradeepa, GR Grimes, Y Kumar, G Olley, GCA Taylor, R Schneider, ...
Nature genetics 48 (6), 681-686, 2016
2422016
Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response
KJ Mackenzie, P Carroll, L Lettice, Ž Tarnauskaitė, K Reddy, F Dix, ...
The EMBO journal 35 (8), 831-844, 2016
2402016
Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly
LA Lettice, I Williamson, JH Wiltshire, S Peluso, PS Devenney, AE Hill, ...
Developmental cell 22 (2), 459-467, 2012
1842012
Human β‐defensin 3 affects the activity of pro‐inflammatory pathways associated with MyD88 and TRIF
F Semple, H MacPherson, S Webb, SL Cox, LJ Mallin, C Tyrrell, ...
European journal of immunology 41 (11), 3291-3300, 2011
1662011
A prenylated dsRNA sensor protects against severe COVID-19
A Wickenhagen, E Sugrue, S Lytras, S Kuchi, M Noerenberg, ML Turnbull, ...
Science 374 (6567), eabj3624, 2021
1502021
BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome
G Olley, M Ansari, H Bengani, GR Grimes, J Rhodes, A von Kriegsheim, ...
Nature Genetics 50 (3), 329-332, 2018
1212018
DNA methylation directs polycomb-dependent 3D genome re-organization in naive pluripotency
K McLaughlin, IM Flyamer, JP Thomson, HK Mjoseng, R Shukla, ...
Cell Reports 29 (7), 1974-1985. e6, 2019
932019
DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans
D Longman, N Hug, M Keith, C Anastasaki, EE Patton, G Grimes, ...
Nucleic acids research 41 (17), 8319-8331, 2013
922013
Anterior-posterior differences in HoxD chromatin topology in limb development
I Williamson, R Eskeland, LA Lettice, AE Hill, S Boyle, GR Grimes, RE Hill, ...
Development 139 (17), 3157-3167, 2012
842012
PRC1 and PRC2 are not required for targeting of H2A. Z to developmental genes in embryonic stem cells
RS Illingworth, CH Botting, GR Grimes, WA Bickmore, R Eskeland
PloS one 7 (4), e34848, 2012
492012
Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins
MM Pradeepa, GR Grimes, GCA Taylor, HG Sutherland, WA Bickmore
Nucleic acids research 42 (14), 9021-9032, 2014
362014
Structural Variants at the BRCA1/2 Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma
A Ewing, A Meynert, M Churchman, GR Grimes, RL Hollis, CS Herrington, ...
Clinical Cancer Research 27 (11), 3201-3214, 2021
342021
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