Stromal Cell PD-L1 Inhibits CD8+ T-cell Antitumor Immune Responses and Promotes Colon Cancer G O'Malley, O Treacy, K Lynch, SD Naicker, NA Leonard, P Lohan, ... Cancer immunology research 6 (11), 1426-1441, 2018 | 74 | 2018 |
Mesenchymal stromal cells (MSCs) and colorectal cancer: a troublesome twosome for the anti-tumour immune response? G O'Malley, M Heijltjes, AM Houston, S Rani, T Ritter, LJ Egan, AE Ryan Oncotarget 7 (37), 60752, 2016 | 65 | 2016 |
Seasonal and daytime variation in multiple immune parameters in humans: Evidence from 329,261 participants of the UK Biobank cohort C Wyse, G O'Malley, AN Coogan, S McConkey, DJ Smith Iscience 24 (4), 2021 | 63 | 2021 |
Targeting colon cancer cell NF-κB promotes an anti-tumour M1-like macrophage phenotype and inhibits peritoneal metastasis AE Ryan, A Colleran, A O'gorman, L O'flynn, J Pindjacova, P Lohan, ... Oncogene 34 (12), 1563-1574, 2015 | 61 | 2015 |
TGF-β1-licensed murine MSCs show superior therapeutic efficacy in modulating corneal allograft immune rejection in vivo K Lynch, O Treacy, X Chen, N Murphy, P Lohan, MN Islam, E Donohoe, ... Molecular Therapy 28 (9), 2023-2043, 2020 | 44 | 2020 |
Evaluation of cartilage repair by mesenchymal stem cells seeded on a PEOT/PBT scaffold in an osteochondral defect V Barron, K Merghani, G Shaw, CM Coleman, JS Hayes, S Ansboro, ... Annals of biomedical engineering 43, 2069-2082, 2015 | 32 | 2015 |
Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment H Egan, O Treacy, K Lynch, NA Leonard, G O’Malley, E Reidy, A O’Neill, ... Cell Reports 42 (5), 2023 | 25 | 2023 |
Evaluation of the Early In Vivo Response of a Functionally Graded Macroporous Scaffold in an Osteochondral Defect in a Rabbit Model V Barron, M Neary, KMS Mohamed, S Ansboro, G Shaw, G O’Malley, ... Annals of biomedical engineering 44, 1832-1844, 2016 | 17 | 2016 |
Stromal cell sialylation suppresses T cells in inflammatory tumour microenvironments: A new tumour stromal cell immune checkpoint? H Egan, O Treacy, K Lynch, NA Leonard, G O’Malley, K De Veirman, ... bioRxiv, 2021.06. 18.447879, 2021 | 2 | 2021 |
Mesenchymal Stromal Cell Sialylation Modulates Antitumor Immune Responses In Multiple Myeloma K Lynch, K De Veirman, H Egan, N Leonard, G O'Malley, T Ritter, A Ryan, ... Clinical Lymphoma, Myeloma and Leukemia 19 (10), e93-e94, 2019 | 1 | 2019 |
Stromal Cell PD-L1 Inhibits CD8 (+) T-cell Antitumor Immune Responses and Promotes Colon Cancer (vol 6, pg 1426, 2018) G O'Malley, O Treacy, K Lynch, SD Naicker, NA Leonard, P Lohan CANCER IMMUNOLOGY RESEARCH 7 (1), 162-162, 2019 | 1 | 2019 |
Extracellular Vesicles Derived From Mesenchymal Stem Cells for Treatment of Ocular Surface Injuries T Ritter, C Lal, O Treacy, G O'Malley, M Naughton, S Naicker, P Lohan, ... The FASEB Journal 30, 373.1-373.1, 2016 | 1 | 2016 |
Mesenchymal stem cell-derived extracellular vesicles promote corneal wound repair T Ritter, GA O'Malley, P Lohan, A Ryan, M Griffin, S Rani Investigative Ophthalmology & Visual Science 56 (7), 716-716, 2015 | 1 | 2015 |
Tumour-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signalling. NA Leonard, SM Corry, E Reidy, H Egan, G O’Malley, K Thompson, ... iScience, 2024 | | 2024 |
864 The mesenchymal stromal compartment in colorectal cancer greatly alters the innate tumour immune microenvironment both in 2D and 3D culture systems N Leonard, O Treacy, H Egan, G O’Malley, ET Bort, E Peerani, T Ritter, ... Journal for ImmunoTherapy of Cancer 8 (Suppl 3), A917-A917, 2020 | | 2020 |
Cellular interactions in the tumour microenvironment during inflammation-associated carcinogenesis G O'Malley | | 2017 |
ASSOCIATED CARCINOGENESIS GA O’Malley National University of Ireland, Galway, 2017 | | 2017 |
Inflammatory signalling in the colon tumour microenvironment enhances stromal cell mediated suppression of anti-tumour immune responses G O'Malley, K Lynch, S Naicker, P Lohan, A Rigalou, T Ritter, LJ Egan, ... Cancer Research 77 (13_Supplement), 2693-2693, 2017 | | 2017 |
Extracellular vesicles derived from human mesenchymal stem cells promote corneal wound repair by increasing epithelial cell proliferation and reducing neovascularisation in a … T Ritter, C Lal, O Treacy, GA O'Malley, S Naicker, H Elbadawy, AE Ryan, ... Investigative Ophthalmology & Visual Science 57 (12), 2016 | | 2016 |