DSigDB: drug signatures database for gene set analysis M Yoo, J Shin, J Kim, KA Ryall, K Lee, S Lee, M Jeon, J Kang, AC Tan Bioinformatics 31 (18), 3069-3071, 2015 | 367 | 2015 |
Monocytic subclones confer resistance to venetoclax-based therapy in patients with acute myeloid leukemia S Pei, DA Pollyea, A Gustafson, BM Stevens, M Minhajuddin, R Fu, ... Cancer discovery 10 (4), 536-551, 2020 | 333 | 2020 |
Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition M Casás-Selves, J Kim, Z Zhang, BA Helfrich, D Gao, CC Porter, ... Cancer research 72 (16), 4154-4164, 2012 | 152 | 2012 |
Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors CJ Henry, M Casás-Selves, J Kim, V Zaberezhnyy, L Aghili, AE Daniel, ... The Journal of clinical investigation 125 (12), 4666-4680, 2015 | 146 | 2015 |
Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma JD Hintzsche, NT Gorden, CM Amato, J Kim, KE Wuensch, SE Robinson, ... Melanoma research 27 (3), 189-199, 2017 | 145 | 2017 |
Regulation of head and neck squamous cancer stem cells by PI3K and SOX2 SB Keysar, PN Le, B Miller, BC Jackson, JR Eagles, C Nieto, J Kim, ... Journal of the National Cancer Institute 109 (1), djw189, 2017 | 119 | 2017 |
Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation G Cavalli, M Koenders, V Kalabokis, J Kim, AC Tan, C Garlanda, ... Rheumatology 55 (12), 2220-2229, 2016 | 114 | 2016 |
ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia MA Gregory, A D’Alessandro, F Alvarez-Calderon, J Kim, T Nemkov, ... Proceedings of the National Academy of Sciences 113 (43), E6669-E6678, 2016 | 104 | 2016 |
Barasertib (AZD1152), a Small Molecule Aurora B Inhibitor, Inhibits the Growth of SCLC Cell Lines In Vitro and In Vivo BA Helfrich, J Kim, D Gao, DC Chan, Z Zhang, AC Tan, PA Bunn Jr Molecular cancer therapeutics 15 (10), 2314-2322, 2016 | 100 | 2016 |
FGFR1 expression levels predict BGJ398 sensitivity of FGFR1-dependent head and neck squamous cell cancers F Göke, A Franzen, TK Hinz, LA Marek, P Yoon, R Sharma, M Bode, ... Clinical cancer research 21 (19), 4356-4364, 2015 | 98 | 2015 |
Integrated genomic analyses identify WEE1 as a critical mediator of cell fate and a novel therapeutic target in acute myeloid leukemia CC Porter, J Kim, S Fosmire, CM Gearheart, A van Linden, D Baturin, ... Leukemia 26 (6), 1266-1276, 2012 | 88 | 2012 |
ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53 KD Sullivan, N Padilla-Just, RE Henry, CC Porter, J Kim, JJ Tentler, ... Nature chemical biology 8 (7), 646-654, 2012 | 82 | 2012 |
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade TW Flaig, M Salzmann-Sullivan, LJ Su, Z Zhang, M Joshi, MA Gijón, J Kim, ... Oncotarget 8 (34), 56051, 2017 | 81 | 2017 |
Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer A Spreafico, JJ Tentler, TM Pitts, AC Tan, MA Gregory, JJ Arcaroli, ... Clinical Cancer Research 19 (15), 4149-4162, 2013 | 76 | 2013 |
A genetic screen identifies TCF3/E2A and TRIAP1 as pathway-specific regulators of the cellular response to p53 activation Z Andrysik, J Kim, AC Tan, JM Espinosa Cell reports 3 (5), 1346-1354, 2013 | 74 | 2013 |
TWIST1-induced miR-424 reversibly drives mesenchymal programming while inhibiting tumor initiation DJ Drasin, AL Guarnieri, D Neelakantan, J Kim, JH Cabrera, CA Wang, ... Cancer research 75 (9), 1908-1921, 2015 | 73 | 2015 |
RIP 1 negatively regulates basal autophagic flux through TFEB to control sensitivity to apoptosis T Yonekawa, G Gamez, J Kim, AC Tan, J Thorburn, J Gump, A Thorburn, ... EMBO reports 16 (6), 700-708, 2015 | 68 | 2015 |
Kinome RNAi screens reveal synergistic targeting of MTOR and FGFR1 pathways for treatment of lung cancer and HNSCC KR Singleton, TK Hinz, EK Kleczko, LA Marek, J Kwak, T Harp, J Kim, ... Cancer research 75 (20), 4398-4406, 2015 | 66 | 2015 |
Genomic signatures of pregnancy-associated breast cancer epithelia and stroma and their regulation by estrogens and progesterone DME Harvell, J Kim, J O’Brien, AC Tan, VF Borges, P Schedin, ... Hormones and Cancer 4, 140-153, 2013 | 59 | 2013 |
Long term storage of dry versus frozen RNA for next generation molecular studies E Seelenfreund, WA Robinson, CM Amato, AC Tan, J Kim, SE Robinson PLoS One 9 (11), e111827, 2014 | 57 | 2014 |