| Deficiency of intestinal mucin‐2 ameliorates experimental alcoholic liver disease in mice P Hartmann, P Chen, HJ Wang, L Wang, DF McCole, K Brandl, P Stärkel, ... Hepatology 58 (1), 108-119, 2013 | 252 | 2013 |
| IBD candidate genes and intestinal barrier regulation DF McCole Inflammatory bowel diseases 20 (10), 1829-1849, 2014 | 184 | 2014 |
| Intestinal Epithelial Cell Apoptosis following Cryptosporidium parvum Infection DF McCole, L Eckmann, F Laurent, MF Kagnoff Infection and immunity 68 (3), 1710-1713, 2000 | 184 | 2000 |
| A crucial role for HVEM and BTLA in preventing intestinal inflammation MW Steinberg, O Turovskaya, RB Shaikh, G Kim, DF McCole, K Pfeffer, ... The Journal of experimental medicine 205 (6), 1463-1476, 2008 | 163 | 2008 |
| Transactivation of the epidermal growth factor receptor in colonic epithelial cells by carbachol requires extracellular release of transforming growth factor-α DF McCole, SJ Keely, RJ Coffey, KE Barrett Journal of Biological Chemistry 277 (45), 42603-42612, 2002 | 143 | 2002 |
| Protection of epithelial barrier function by the Crohn's disease associated gene protein tyrosine phosphatase n2 M Scharl, G Paul, A Weber, BC Jung, MJ Docherty, M Hausmann, ... Gastroenterology 137 (6), 2030-2040. e5, 2009 | 140 | 2009 |
| Pathogenesis of Cryptosporidium parvum infection F Laurent, D McCole, L Eckmann, MF Kagnoff Microbes and Infection 1 (2), 141-148, 1999 | 139 | 1999 |
| Mechanisms of intestinal epithelial barrier dysfunction by adherent-invasive Escherichia coli A Shawki, DF McCole Cellular and molecular gastroenterology and hepatology 3 (1), 41-50, 2017 | 125 | 2017 |
| CXCR2-dependent mucosal neutrophil influx protects against colitis-associated diarrhea caused by an attaching/effacing lesion-forming bacterial pathogen ME Spehlmann, SM Dann, P Hruz, E Hanson, DF McCole, L Eckmann The Journal of Immunology 183 (5), 3332-3343, 2009 | 122 | 2009 |
| AMP-activated protein kinase mediates the interferon-γ-induced decrease in intestinal epithelial barrier function M Scharl, G Paul, KE Barrett, DF McCole Journal of Biological Chemistry 284 (41), 27952-27963, 2009 | 116 | 2009 |
| Cholera toxin disrupts barrier function by inhibiting exocyst-mediated trafficking of host proteins to intestinal cell junctions A Guichard, B Cruz-Moreno, B Aguilar, NM van Sorge, J Kuang, ... Cell host & microbe 14 (3), 294-305, 2013 | 107 | 2013 |
| Protein tyrosine phosphatase N2 regulates TNFα-induced signalling and cytokine secretion in human intestinal epithelial cells M Scharl, DF McCole, A Weber, SR Vavricka, P Frei, S Kellermeier, ... Gut 60 (2), 189-197, 2011 | 91 | 2011 |
| PTPN2 regulates interactions between macrophages and intestinal epithelial cells to promote intestinal barrier function MR Spalinger, A Sayoc-Becerra, AN Santos, A Shawki, V Canale, ... Gastroenterology 159 (5), 1763-1777. e14, 2020 | 89 | 2020 |
| PTPN2 regulates inflammasome activation and controls onset of intestinal inflammation and colon cancer MR Spalinger, R Manzini, L Hering, JB Riggs, C Gottier, S Lang, K Atrott, ... Cell reports 22 (7), 1835-1848, 2018 | 89 | 2018 |
| Protein tyrosine phosphatase nonreceptor type 2 regulates autophagosome formation in human intestinal cells M Scharl, KA Wojtal, HM Becker, A Fischbeck, P Frei, J Arikkat, T Pesch, ... Inflammatory bowel diseases 18 (7), 1287-1302, 2012 | 89 | 2012 |
| Crohn's Disease-associated Polymorphism Within the PTPN2 Gene Affects Muramyl-Dipeptide-induced Cytokine Secretion and Autophagy M Scharl, J Mwinyi, A Fischbeck, K Leucht, JJ Eloranta, J Arikkat, T Pesch, ... Inflammatory bowel diseases 18 (5), 900-912, 2012 | 86 | 2012 |
| The JAK-inhibitor tofacitinib rescues human intestinal epithelial cells and colonoids from cytokine-induced barrier dysfunction A Sayoc-Becerra, M Krishnan, S Fan, J Jimenez, R Hernandez, K Gibson, ... Inflammatory Bowel Diseases 26 (3), 407-422, 2020 | 78 | 2020 |
| Protein tyrosine phosphatase non-receptor Type 2 regulates IFN-γ-induced cytokine signaling in THP-1 monocytes M Scharl, P Hruz, DF McCole Inflammatory bowel diseases 16 (12), 2055-2064, 2010 | 77 | 2010 |
| Epidermal growth factor partially restores colonic ion transport responses in mouse models of chronic colitis DF McCole, G Rogler, N Varki, KE Barrett Gastroenterology 129 (2), 591-608, 2005 | 73 | 2005 |
| Varied role of the gut epithelium in mucosal homeostasis DF McCole, KE Barrett Current opinion in gastroenterology 23 (6), 647-654, 2007 | 72 | 2007 |
