Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen CK Stover, XQ Pham, AL Erwin, SD Mizoguchi, P Warrener, MJ Hickey, ... Nature 406 (6799), 959-964, 2000 | 5597 | 2000 |
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia Cancer Genome Atlas Research Network New England Journal of Medicine 368 (22), 2059-2074, 2013 | 4719 | 2013 |
Comprehensive transposon mutant library of Pseudomonas aeruginosa MA Jacobs, A Alwood, I Thaipisuttikul, D Spencer, E Haugen, S Ernst, ... Proceedings of the National Academy of Sciences 100 (24), 14339-14344, 2003 | 1342 | 2003 |
CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer M Griffith, NC Spies, K Krysiak, JF McMichael, AC Coffman, AM Danos, ... Nature genetics 49 (2), 170-174, 2017 | 549 | 2017 |
The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers DA Russler-Germain, DH Spencer, MA Young, TL Lamprecht, CA Miller, ... Cancer cell 25 (4), 442-454, 2014 | 469 | 2014 |
Functional heterogeneity of genetically defined subclones in acute myeloid leukemia JM Klco, DH Spencer, CA Miller, M Griffith, TL Lamprecht, M O’Laughlin, ... Cancer cell 25 (3), 379-392, 2014 | 432 | 2014 |
Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients DA D'Argenio, M Wu, LR Hoffman, HD Kulasekara, E Déziel, EE Smith, ... Molecular microbiology 64 (2), 512-533, 2007 | 421 | 2007 |
Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia JM Klco, CA Miller, M Griffith, A Petti, DH Spencer, S Ketkar-Kulkarni, ... Jama 314 (8), 811-822, 2015 | 381 | 2015 |
Whole-Genome Sequence Variation among Multiple Isolates of Pseudomonas aeruginosa DH Spencer, A Kas, EE Smith, CK Raymond, EH Sims, M Hastings, ... Journal of bacteriology 185 (4), 1316-1325, 2003 | 268 | 2003 |
Clinical next‐generation sequencing in patients with non–small cell lung cancer IS Hagemann, S Devarakonda, CM Lockwood, DH Spencer, K Guebert, ... Cancer 121 (4), 631-639, 2015 | 226 | 2015 |
CpG island hypermethylation mediated by DNMT3A is a consequence of AML progression DH Spencer, DA Russler-Germain, S Ketkar, NM Helton, TL Lamprecht, ... Cell 168 (5), 801-816. e13, 2017 | 221 | 2017 |
Evidence for Diversifying Selection at the Pyoverdine Locus of Pseudomonas aeruginosa EE Smith, EH Sims, DH Spencer, R Kaul, MV Olson Journal of bacteriology 187 (6), 2138-2147, 2005 | 206 | 2005 |
Comparison of clinical targeted next-generation sequence data from formalin-fixed and fresh-frozen tissue specimens DH Spencer, JK Sehn, HJ Abel, MA Watson, JD Pfeifer, EJ Duncavage The Journal of molecular diagnostics 15 (5), 623-633, 2013 | 204 | 2013 |
Genome sequencing as an alternative to cytogenetic analysis in myeloid cancers EJ Duncavage, MC Schroeder, M O’Laughlin, R Wilson, S MacMillan, ... New England Journal of Medicine 384 (10), 924-935, 2021 | 199 | 2021 |
Validation of a next-generation sequencing assay for clinical molecular oncology CE Cottrell, H Al-Kateb, AJ Bredemeyer, EJ Duncavage, DH Spencer, ... The Journal of molecular diagnostics 16 (1), 89-105, 2014 | 199 | 2014 |
Genetic Variation at the O-Antigen Biosynthetic Locus in Pseudomonas aeruginosa CK Raymond, EH Sims, A Kas, DH Spencer, TV Kutyavin, RG Ivey, ... Journal of bacteriology 184 (13), 3614-3622, 2002 | 197 | 2002 |
Genomic impact of transient low-dose decitabine treatment on primary AML cells JM Klco, DH Spencer, TL Lamprecht, SM Sarkaria, T Wylie, V Magrini, ... Blood, The Journal of the American Society of Hematology 121 (9), 1633-1643, 2013 | 169 | 2013 |
Performance of common analysis methods for detecting low-frequency single nucleotide variants in targeted next-generation sequence data DH Spencer, M Tyagi, F Vallania, AJ Bredemeyer, JD Pfeifer, RD Mitra, ... The Journal of Molecular Diagnostics 16 (1), 75-88, 2014 | 158 | 2014 |
Detection of FLT3 internal tandem duplication in targeted, short-read-length, next-generation sequencing data DH Spencer, HJ Abel, CM Lockwood, JE Payton, P Szankasi, TW Kelley, ... The Journal of molecular diagnostics 15 (1), 81-93, 2013 | 145 | 2013 |
Genome mosaicism is conserved but not unique in Pseudomonas aeruginosa isolates from the airways of young children with cystic fibrosis RK Ernst, DA D′ Argenio, JK Ichikawa, MG Bangera, S Selgrade, ... Environmental microbiology 5 (12), 1341-1349, 2003 | 127 | 2003 |