Computational techniques for ECG analysis and interpretation in light of their contribution to medical advances A Lyon, A Mincholé, JP Martínez, P Laguna, B Rodriguez Journal of The Royal Society Interface 15 (138), 20170821, 2018 | 230 | 2018 |
Machine learning in the electrocardiogram A Mincholé, J Camps, A Lyon, B Rodríguez Journal of electrocardiology 57, S61-S64, 2019 | 138 | 2019 |
Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies H Sutanto, A Lyon, J Lumens, U Schotten, D Dobrev, J Heijman Progress in biophysics and molecular biology 157, 54-75, 2020 | 97 | 2020 |
Distinct ECG phenotypes identified in hypertrophic cardiomyopathy using machine learning associate with arrhythmic risk markers A Lyon, R Ariga, A Mincholé, M Mahmod, E Ormondroyd, P Laguna, ... Frontiers in physiology 9, 213, 2018 | 88 | 2018 |
Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop B Rodriguez, A Carusi, N Abi-Gerges, R Ariga, O Britton, G Bub, ... Ep Europace 18 (9), 1287-1298, 2015 | 53 | 2015 |
Electrocardiogram phenotypes in hypertrophic cardiomyopathy caused by distinct mechanisms: apico-basal repolarization gradients vs. Purkinje-myocardial coupling abnormalities A Lyon, A Bueno-Orovio, E Zacur, R Ariga, V Grau, S Neubauer, ... EP Europace 20 (suppl_3), iii102-iii112, 2018 | 45 | 2018 |
ESC Scientific Document Group. 2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for … AR Lyon, T López-Fernández, LS Couch, R Asteggiano, MC Aznar, ... Eur Heart J 43 (41), 4229-4361, 2022 | 42 | 2022 |
Improving long QT syndrome diagnosis by a polynomial-based T-wave morphology characterization BJM Hermans, FC Bennis, AS Vink, T Koopsen, A Lyon, AAM Wilde, ... Heart Rhythm 17 (5), 752-758, 2020 | 29 | 2020 |
The prognostic impact of mechanical atrial dysfunction and atrial fibrillation in heart failure with preserved ejection fraction J Weerts, A Barandiarán Aizpurua, MTHM Henkens, A Lyon, ... European Heart Journal-Cardiovascular Imaging 23 (1), 74-84, 2022 | 23 | 2022 |
Both beat-to-beat changes in RR-interval and left ventricular filling time determine ventricular function during atrial fibrillation A Lyon, M van Mourik, L Cruts, J Heijman, SCAM Bekkers, U Schotten, ... EP Europace 23 (Supplement_1), i21-i28, 2021 | 17 | 2021 |
Parameter subset reduction for patient-specific modelling of arrhythmogenic cardiomyopathy-related mutation carriers in the CircAdapt model N Van Osta, A Lyon, F Kirkels, T Koopsen, T Van Loon, MJ Cramer, ... Philosophical Transactions of the Royal Society A 378 (2173), 20190347, 2020 | 17 | 2020 |
Differentiating the effects of β-adrenergic stimulation and stretch on calcium and force dynamics using a novel electromechanical cardiomyocyte model A Lyon, LJ Dupuis, T Arts, HJGM Crijns, FW Prinzen, T Delhaas, ... American Journal of Physiology-Heart and Circulatory Physiology 319 (3 …, 2020 | 15 | 2020 |
Electromechanical substrate characterization in arrhythmogenic cardiomyopathy using imaging-based patient-specific computer simulations N Van Osta, F Kirkels, A Lyon, T Koopsen, T Van Loon, MJ Cramer, ... EP Europace 23 (Supplement_1), i153-i160, 2021 | 13 | 2021 |
Uncertainty quantification of regional cardiac tissue properties in arrhythmogenic cardiomyopathy using adaptive multiple importance sampling N Van Osta, FP Kirkels, T Van Loon, T Koopsen, A Lyon, R Meiburg, ... Frontiers in physiology 12, 738926, 2021 | 11 | 2021 |
Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation: Analysis of AF-RISK MJW Van Mourik, VA Arita, A Lyon, J Lumens, R Ruben, JP van Melle, ... International Journal of Cardiology 360, 29-35, 2022 | 9 | 2022 |
Improving the clinical understanding of hypertrophic cardiomyopathy by combining patient data, machine learning and computer simulations: a case study A Lyon, A Mincholé, A Bueno-Orovio, B Rodriguez Morphologie 103 (343), 169-179, 2019 | 8 | 2019 |
Computational modeling of cardiac electrophysiology and arrhythmogenesis NA Trayanova, A Lyon, J Shade, J Heijman Physiological Reviews, 2023 | 7 | 2023 |
In silico Identification of Disrupted Myocardial Calcium Homeostasis as Proarrhythmic Trigger in Arrhythmogenic Cardiomyopathy A Lyon, CJM Van Opbergen, M Delmar, J Heijman, TAB Van Veen Frontiers in physiology 12, 732573, 2021 | 6 | 2021 |
Extraction of morphological QRS-based biomarkers in hypertrophic cardiomyopathy for risk stratification using L1 regularized logistic regression A Lyon, A Mincholé, R Ariga, P Laguna, S Neubauer, H Watkins, ... 2015 Computing in Cardiology Conference (CinC), 9-12, 2015 | 3 | 2015 |
Increased Chamber Resting Tone Is a Key Determinant of Left Ventricular Diastolic Dysfunction M Tamargo, P Martínez-Legazpi, MÁ Espinosa, A Lyon, I Méndez, ... Circulation: Heart Failure 16 (12), e010673, 2023 | 2 | 2023 |