Mitochondrial ADP/ATP carrier can be reversibly converted into a large channel by Ca2+ N Brustovetsky, M Klingenberg Biochemistry 35 (26), 8483-8488, 1996 | 540 | 1996 |
Calcium‐induced Cytochrome c release from CNS mitochondria is associated with the permeability transition and rupture of the outer membrane N Brustovetsky, T Brustovetsky, R Jemmerson, JM Dubinsky Journal of neurochemistry 80 (2), 207-218, 2002 | 303 | 2002 |
Enhancing hematopoietic stem cell transplantation efficacy by mitigating oxygen shock CR Mantel, HA O’Leary, BR Chitteti, XX Huang, S Cooper, G Hangoc, ... Cell 161 (7), 1553-1565, 2015 | 302 | 2015 |
Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex JM Brittain, DB Duarte, SM Wilson, W Zhu, C Ballard, PL Johnson, N Liu, ... Nature medicine 17 (7), 822-829, 2011 | 246 | 2011 |
Increased susceptibility of striatal mitochondria to calcium-induced permeability transition N Brustovetsky, T Brustovetsky, KJ Purl, M Capano, M Crompton, ... Journal of Neuroscience 23 (12), 4858-4867, 2003 | 215 | 2003 |
Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria N Brustovetsky, JM Dubinsky Journal of Neuroscience 20 (22), 8229-8237, 2000 | 208 | 2000 |
Dual responses of CNS mitochondria to elevated calcium N Brustovetsky, JM Dubinsky Journal of Neuroscience 20 (1), 103-113, 2000 | 168 | 2000 |
On the mechanisms of neuroprotection by creatine and phosphocreatine N Brustovetsky, T Brustovetsky, JM Dubinsky Journal of neurochemistry 76 (2), 425-434, 2001 | 163 | 2001 |
A large Ca2+-dependent channel formed by recombinant ADP/ATP carrier from Neurospora crassa resembles the mitochondrial permeability transition pore N Brustovetsky, M Tropschug, S Heimpel, D Heidkämper, M Klingenberg Biochemistry 41 (39), 11804-11811, 2002 | 151 | 2002 |
The reconstituted ADP/ATP carrier can mediate H+ transport by free fatty acids, which is further stimulated by mersalyl. N Brustovetsky, M Klingenberg Journal of Biological Chemistry 269 (44), 27329-27336, 1994 | 141 | 1994 |
Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol RR Patel, C Barbosa, T Brustovetsky, N Brustovetsky, TR Cummins Brain 139 (8), 2164-2181, 2016 | 136 | 2016 |
Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition induces neurotoxicity via dysregulation of glutamate/calcium signaling and hyperexcitability NM Ashpole, W Song, T Brustovetsky, EA Engleman, N Brustovetsky, ... Journal of Biological Chemistry 287 (11), 8495-8506, 2012 | 125 | 2012 |
Kinetics of electrogenic transport by the ADP/ATP carrier T Gropp, N Brustovetsky, M Klingenberg, V Müller, K Fendler, E Bamberg Biophysical journal 77 (2), 714-726, 1999 | 118 | 1999 |
Age‐dependent changes in the calcium sensitivity of striatal mitochondria in mouse models of Huntington's disease N Brustovetsky, R LaFrance, KJ Purl, T Brustovetsky, CD Keene, WC Low, ... Journal of neurochemistry 93 (6), 1361-1370, 2005 | 116 | 2005 |
Neuroprotection against traumatic brain injury by a peptide derived from the collapsin response mediator protein 2 (CRMP2) JM Brittain, L Chen, SM Wilson, T Brustovetsky, X Gao, NM Ashpole, ... Journal of Biological Chemistry 286 (43), 37778-37792, 2011 | 102 | 2011 |
Two pathways for tBID‐induced cytochrome c release from rat brain mitochondria: BAK‐ versus BAX‐dependence N Brustovetsky, JM Dubinsky, B Antonsson, R Jemmerson Journal of neurochemistry 84 (1), 196-207, 2003 | 85 | 2003 |
Calcium-dependent spontaneously reversible remodeling of brain mitochondria N Shalbuyeva, T Brustovetsky, A Bolshakov, N Brustovetsky Journal of Biological Chemistry 281 (49), 37547-37558, 2006 | 84 | 2006 |
Collapsin response mediator protein 2 (CRMP2) interacts with N-methyl-D-aspartate (NMDA) receptor and Na+/Ca2+ exchanger and regulates their functional activity T Brustovetsky, JJ Pellman, XF Yang, R Khanna, N Brustovetsky Journal of Biological Chemistry 289 (11), 7470-7482, 2014 | 78 | 2014 |
Lithium desensitizes brain mitochondria to calcium, antagonizes permeability transition, and diminishes cytochrome C release N Shalbuyeva, T Brustovetsky, N Brustovetsky Journal of Biological Chemistry 282 (25), 18057-18068, 2007 | 76 | 2007 |
Cytochrome c Release from CNS Mitochondria and Potential for Clinical Intervention in Apoptosis-Mediated CNS Diseases R Jemmerson, JM Dubinsky, N Brustovetsky Antioxidants & redox signaling 7 (9-10), 1158-1172, 2005 | 71 | 2005 |